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1. Kaneesha is 26 years old and her husband Marshall is 28. When Kaneesha becomes pregnant, she asks her obstetrician about prenatal tests, because a cousin had a child with Down syndrome at age of 27, and her two sisters have each had 2 miscarriages. She tells the doctor of this family history. This is her first pregnancy, although they have been trying for several years. The doctor advises Kanesssha to have a maternal serum marker (blood) test, called "triple-test", instead of amniocentesis, because she is under age 35. The triple test is so-called because it measures levels of 3 substances (alpha-fetoprotein, human chorionic gonadotropin, and a form of estrogen). The doctor tells the couple that the test is only a 'screen', and can detect up to 60% of Down syndrome cases that are caused by and extra chromosome 21. Kaneesha gives birth to Nathaniel, who has Down syndrome, but his karyotype does NOT show a trisomy. Kaneesha and Marshall sue the obstetrician, on the grounds that they were advised to take a wrong prenatal test. A. Why did the doctor advise Kaneesha not to have amniocentesis and why should she have had the amnio? X B. How can Nathaniel have Down syndrome if his cells have 46 chromosomes? C. What is the risk of Down syndrome in future conceptions for the couple? Accessibility: Good to go

1. Kaneesha is 26 years old and her husband Marshall is 28. When Kaneesha becomes pregnant, she asks her obstetrician about prenatal tests, because a cousin had a child with Down syndrome at age of 27, and her two sisters have each had 2 miscarriages. She tells the doctor of this family history. This is her first pregnancy, although they have been trying for several years. The doctor advises Kanesssha to have a maternal serum marker (blood) test, called "triple-test", instead of amniocentesis, because she is under age 35. The triple test is so-called because it measures levels of 3 substances (alpha-fetoprotein, human chorionic gonadotropin, and a form of estrogen). The doctor tells the couple that the test is only a 'screen', and can detect up to 60% of Down syndrome cases that are caused by and extra chromosome 21. Kaneesha gives birth to Nathaniel, who has Down syndrome, but his karyotype does NOT show a trisomy. Kaneesha and Marshall sue the obstetrician, on the grounds that they were advised to take a wrong prenatal test. A. Why did the doctor advise Kaneesha not to have amniocentesis and why should she have had the amnio? X B. How can Nathaniel have Down syndrome if his cells have 46 chromosomes? C. What is the risk of Down syndrome in future conceptions for the couple? Accessibility: Good to go

Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy
Section: Chapter Questions
Problem 1CS: Would ISCI be an option? Why or why not? Jan, a 32-year-old woman, and her husband, Darryl, have...
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O $ 1. Kaneesha is 26 years old and her husband Marshall is 28. When Kaneesha becomes pregnant, she asks her obstetrician about prenatal tests, because a cousin had a child with Down syndrome at age of 27, and her two sisters have each had 2 miscarriages. She tells the doctor of this family history. This is her first pregnancy, although they have been trying for several years. 4 SEP 26 The doctor advises Kanesssha to have a maternal serum marker (blood) test, called "triple-test", instead of amniocentesis, because she is under age 35. The triple test is so-called because it measures levels of 3 substances (alpha-fetoprotein, human chorionic gonadotropin, and a form of estrogen). The doctor tells the couple that the test is only a 'screen', and can detect up to 60% of Down syndrome cases that are caused by and extra chromosome 21. Kaneesha gives birth to Nathaniel, who has Down syndrome, but his karyotype does NOT show a trisomy. Kaneesha and Marshall sue the obstetrician, on the grounds that they were advised to take a wrong prenatal test. 888 A. Why did the doctor advise Kaneesha not to have amniocentesis and why should she have had the amnio? I s) Accessibility: Good to go B. C. % How can Nathaniel have Down syndrome if his cells have 46 chromosomes? 5 What is the risk of Down syndrome in future conceptions for the couple? 6 A MacBook Pro A & 7 * 00 9 Focus P
Transcribed Image Text:O $ 1. Kaneesha is 26 years old and her husband Marshall is 28. When Kaneesha becomes pregnant, she asks her obstetrician about prenatal tests, because a cousin had a child with Down syndrome at age of 27, and her two sisters have each had 2 miscarriages. She tells the doctor of this family history. This is her first pregnancy, although they have been trying for several years. 4 SEP 26 The doctor advises Kanesssha to have a maternal serum marker (blood) test, called "triple-test", instead of amniocentesis, because she is under age 35. The triple test is so-called because it measures levels of 3 substances (alpha-fetoprotein, human chorionic gonadotropin, and a form of estrogen). The doctor tells the couple that the test is only a 'screen', and can detect up to 60% of Down syndrome cases that are caused by and extra chromosome 21. Kaneesha gives birth to Nathaniel, who has Down syndrome, but his karyotype does NOT show a trisomy. Kaneesha and Marshall sue the obstetrician, on the grounds that they were advised to take a wrong prenatal test. 888 A. Why did the doctor advise Kaneesha not to have amniocentesis and why should she have had the amnio? I s) Accessibility: Good to go B. C. % How can Nathaniel have Down syndrome if his cells have 46 chromosomes? 5 What is the risk of Down syndrome in future conceptions for the couple? 6 A MacBook Pro A & 7 * 00 9 Focus P
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