Q: a. The eyeless gene is required for eye formation in Drosophila. It encodes a homeodomain. What…
A: Genes are the hereditary unit of an organism. The genes have DNA (deoxyribonucleic acid) which code…
Q: Researchers know that Fru-M controls male sexualbehavior in Drosophila because inappropriate…
A: In Drosophila melanogaster, sex is determined by cell and tissue-specific signals and not by…
Q: 2. Define the term maternal effect genes, and explain whythe protein products of some of these genes…
A: The pattern of body development in terms of segmentation is a morphological growth in animals from…
Q: The SRY gene: O A. is located in the pseudoautosomal region of the Y chromosome B. encodes a histone…
A: Sex determination in mammals: The sex of the mammals is determined by sex chromosomes. In mammals…
Q: You are studying Hox genes in crane flies (Leptotarsus testaceus). The cranefly genome is sequenced,…
A: To find: Where the homologue of EVE gene is expressed in cranefly embryos
Q: The easily observed external structures in insects, such as different pairs of legs, antennae, and…
A: The disc-shaped structure that arises from the Imago is known as an imaginary disc. Imago is a Latin…
Q: describe the arrangment of Hox genes on each chromosome in mammals in relation to their expression…
A: Hox genes are group of related genes that determine the basic structure and the composition or…
Q: We know quite a bit about Notch/Delta and Hes gene oscillations during embryonic development. What…
A: Embryogenesis includes coordinated cycles of cell proliferation and differentiation. Mammalian Hes…
Q: 29. The predominant mechanism of regulating genes differentially expressed in parenchymal cells is:…
A: The correct answer to this particular question will be, A. selective gene loss.
Q: Insulin-like growth factor 2 (IGF2) is located on chromosome 11. My maternal copy of chromosome 11…
A: The IGF2 gene provides instructions for making a protein called insulin-like growth factor 2. It…
Q: Gene dosage—the number of copies of a gene that areactively being expressed—is important to proper…
A: The number of copies of a particular gene, present in the genome refers to gene dosage. A proper…
Q: Gli3 and distal Hox gene expression Gradual reduction in distal Hoxd dosage Ноxd13 +/+ +/- +/+ +/-…
A: Hox genes specifies the identity of the limb region. It also sepcifies whether a particular…
Q: 1. Which of the following ensures that most genes on one X chromosome are not expressed in female…
A: Female cells have two X chromosomes while males have one X and one Y. This means females have twice…
Q: Which of the following applies to the female sex determination in Drosophila melanogaster fruit…
A: Sex-lethal (Sxl) is the master switch gene for somatic sex determination in Drosophila melanogaster.…
Q: D. In mice, the Igf2 gene inherited from the mother is never expressed in her offspring? Explain.…
A: Determine: How lgt2 Gene inherited from mother never expressed in her offspring. What gene deleted…
Q: Developmental genes are often highly conserved. However, organisms with very similar genes can…
A: DEVELOPMENTAL GENES:- Genes that are responsible for controlling the transcription and translation…
Q: The anterior structure of the Drosophila is promoted by which of the following events?* a. nanos…
A: The Drosophila embryo provides an excellent model for studying gene regulatory networks. In…
Q: 5. Consider the use of GWAS to identify mutations that contribute to an increased risk of pancreatic…
A: Cancer is a highly fatal disease that may occur due to the exposure towards high ultra violet rays.…
Q: 29. The predominant mechanism of regulating genes differentially expressed in parenchymal cells is:…
A: Differential gene expression refers to the expression of genes in the form of different types of…
Q: Can the compound cause expression for each gene.
A: Since you have asked multiple question, we will solve the first question for you. If you want any…
Q: Which of the following statements is incorrect? a. Some gene expression patterns can be passed to an…
A: The epigenetic regulation of gene expression is considered a very common process. This plays a major…
Q: The gain-of-function ANTP mutant in Drosophila has legs growing in the place of antennae. What is…
A: Hox genes are the genes which contain homebox sequence and these are responsible for the…
Q: HAT48 is a histone acetyltransferase that binds DNA next to the promoter of the OVU3 gene. Likely,…
A: Acetyltransferases are the enzymes that catalyze the transfer of acetyl groups. Histones are the…
Q: In mammalian females, the majority of one X chromosome's genes are shut down in a process called X…
A: Step 1- In mammalian females , the majority of one chromosomes gene , are shut down in a process…
Q: 2. a. You want to create a genetic construct that will express GFP in Drosophila. In addition to the…
A: Green fluorescent protein (GFP) contains 238 amino acids which are responsible for bright green…
Q: How does the protein SF 9G8 affect body fat in Drosophila melanogaster (fruit flies)?
A: Drosophila melanogaster is a fly species belonging to the Drosophilidae family. The species is often…
Q: Contrast the role of the MCM1 protein in different yeastcell types shown in Figure 12-10. How are…
A: Mcm1 is a multifunctional protein in Saccharomyces cerevisiae that has a role in both the…
Q: Which of the following statements about sex determination in Drosophila is false? Males…
A: Sex determination is determined by, cells from females contain two X chromosomes, and cells from…
Q: Due to a nucleotide substitution, the fourth residue of H3 in a specific tissue cell of an organism…
A: Protein domains are the structural units of protein that are responsible for specific function of…
Q: The easily observed external structures in insects, such as different pairs of legs, antennae, and…
A: Imaginal disc are the disc shaped structure originates from the Imago. Imago is latin word which…
Q: Explain what a morphogen is, and describe how it exerts its effects. What do you expect will happen…
A: It is a chemical which can cause or determine morphogenesis.
Q: Which of the following proteins is a combinatorial transcriptional regulator in Drosophila that…
A: There are few important points : Combinatorial transcriptional regulator : It is a particular…
Q: 1. After receiving the SR signal, stem cells in the developing organism will have an increased…
A: Gene is unit of DNA that is usually located on a chromosome and that controls the development of one…
Q: A key event that initially determines female or male development in Drosophila is the a.…
A: DEVELOPMENT IN DROSOPHILA:- The life cycle of Drosophila has a number of stages:- 1)Embryogenesis…
Q: Figure 2 illustrates how Pitx1 transcription is regulated in different tissues. The center image is…
A: Since you have posted a question with multiple sub-parts, we will solve first three sub-parts for…
Q: Homeotic genes(A) encode transcription factors that control the expression ofgenes responsible for…
A: Gene is the basic subunit of the chromosome and it refers to the nucleotide sequence. It is known to…
Q: 6. Suppose a particular gene is required for early development and also later for development of a…
A: Mosaic analysis with a repressible cell marker is a technique used to create homozygous mutant…
Q: In the early Drosophila embryo, there seems to be no requirement for the usual forms of cell–cell…
A: Drosophila is the genus of fly that belongs to the family of Drosophilidae that is commonly known as…
Q: 2. Some mutant corn plants start seed germination while the kernels are still on the cob, a…
A: Vivipary is the phenomenon in which seed germination occurs prematurely while they are still…
Q: Aurora A Aurora A is a protein that acts as a kinase (transfers phosphates to molecules). Many types…
A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…
Q: You have discovered a gene in mice that is similar to a gene in yeast. How might you determine…
A: Genes carry coded genetic information in the form of specific nucleotide sequences. This specific…
Q: Dylan Mortimer an artist struggled with Cystic fibrosis a disease causes the body to produce thick…
A: Cystic fibrosis is a progressive disease. Usually it can be detected in a person as early as first…
Q: Discuss the roles of epidermal growth factor receptor (EGFR) in normal cell signalling transduction…
A: Note: Since you have asked multiple question, we will solve the first question for you. If you want…
Q: The figure below shows the distribution of proteins during embryo development in Drosophila. These…
A: The development of the embryo in drosophila is an orderly process of change that is regulated by the…
Q: Mutations of regulatory elements of developmental genes may have a variety of effects. If a mutation…
A: The mutation is the change in the nucleotide sequences that lead to incorrect gene expression and…
Q: Why is folate recommended on pregnant women? Connect this to epigenetics.
A: Introduction Nutrients are important for overall growth and development of the organisms. These are…
Q: What piece of a transcript is utilized to localize the mRNA and why is this critical to development?…
A: DNA is transcribed into primary transcript during transcription.
Q: Developmental abnormalities can result from: 1. Under expression of some genes 2. All of these…
A: Developmental abnormalities can manifest themselves in a number of ways. Genetic (inherited),…
Q: What is the function of Drosophila melanogaster RNA polymerase II in the cell
A: Introduction Drosophila melanogaster is used as a model organism to study disciplines ranging from…
Q: Please discuss the effect of epigenetic posttranslational modifications on cancer development…
A: Hi, this is an opinion-based question and requires an outside source, therefore, I am explaining in…
1. How do muscle cells remain differentiated as muscle cells?
2. A mutation occurs in the Drosophila doublesex gene that prevents Tra from binding to the dsx RNA transcript. What would be the consequences of this mutation for Dsx protein expression in males? In females?
Step by step
Solved in 2 steps
- A mutation occurs in the Drosophila doublesex gene that prevents Tra from binding to the dsx RNA transcript. What would be the consequences of this mutation for Dsx protein expression in males? In females?2. a. You want to create a genetic construct that will express GFP in Drosophila. In addition to the GFPcoding sequence, what DNA element(s) must youinclude in order to express this protein in flies if theconstruct were integrated into the Drosophila genome? Where should such DNA element(s) be located? How would you ensure that GFP is expressedonly in certain tissues of the fly, such as the wing?b. Suppose you insert the GFP coding region plus allof the DNA elements required by the answer to part(a)—except the enhancer—between inverted repeatsfound at the ends of a particular transposable element.Because all of the DNA sequences located betweenthese inverted repeats can move from place to placein the Drosophila genome, you can generate manydifferent fly strains, each with the construct integrated at a different genomic location. You now examine animals from each strain for GFPfluorescence. Animals from different strains showdifferent patterns: some glow green in the eyes,others in…12. a. You want to create a genetic construct that will express GFP in Drosophila. In addition to the GFPcoding sequence, what DNA element(s) must youinclude in order to express this protein in flies if theconstruct were integrated into the Drosophila genome? Where should such DNA element(s) be located? How would you ensure that GFP is expressedonly in certain tissues of the fly, such as the wing?b. Suppose you insert the GFP coding region plus allof the DNA elements required by the answer to part(a)—except the enhancer—between inverted repeatsfound at the ends of a particular transposable element.Because all of the DNA sequences located betweenthese inverted repeats can move from place to placein the Drosophila genome, you can generate manydifferent fly strains, each with the construct integrated at a different genomic location. You now examine animals from each strain for GFPfluorescence. Animals from different strains showdifferent patterns: some glow green in the eyes,others in…
- What would be the most likely effect of inhibiting the translation of hunchback mRNA throughout a Drosophila embryo?1. How is PKD inherited? What gene is responsible for the expression of PK enzyme ?19. After showing that Sox2 is able to bind to the Hes5 promoter, what are two future experiments that could be done to further highlight Sox2's role in neurogenesis?
- 1a. Provide a paper published in a scientific journal between January 2018 and September 2022 that addresses the role of an example of histone modification in affecting expression of a gene by altering histone acetylation/chromatin state of the DNA encoding that gene.1A.If transcription factor G is downstream of EGFR and upregulates gene H, what happens to H if Grb2 has an ER signal sequence? 1B. If transcription factor A is phosphorylated by Akt and upregulates gene B, what happens to gene B if a PI3K inhibitor is added? Choices are: A. No expression of the gene B. Upregulation even in the absence of stimulation/ EGF C. Upregulation but only in the presence of cytokine/ EGF1a. Provide a paper published in a scientific journal between January 2018 and September 2022 that addresses the role of an example of histone modification in affecting expression of a gene by altering histone acetylation/chromatin state of the DNA encoding that gene. What organism and/or cell type did the authors do their study in?
- 18. Two eukaryotic genes (A and B) are involved in two different metabolic pathways, and each has a control element sequence (enhancer) upstream of their coding sequence. The interaction of these enhancers with specific transcription factors determines the level of gene expression. These two genes are expressed differentially in two different tissues (tissue 1 and tissue 2) according to the table below. Tissue 1 Tissue 2 Gene A OFF ON Gene B ON OFF What can explain this pattern of gene expression? A. Gene A and B have different control element sequences and the cells of tissue 1 and tissue 2 express the same transcription factors (at the same concentration and at the same time). B. Gene A and B have the same control element sequences and the cells of tissue 1 and tissue 2 express different transcription factors. C. Gene A and B have the same control element sequences and the cells of tissue 1 and tissue 2 express the same transcription factors (at the same concentration and at the same…1. Which of the following ensures that most genes on one X chromosome are not expressed in female animal cells? a.Knockout b.Circadian rhythm c.Repressors d,X chromosome inactivation 2. Which of the following is a function of histones in the process of gene expression? a.They wrap or unwind DNA and affect which DNA regions are accessible to RNA polymerase. b.They transport mRNA to key regions in the cytoplasm. c.They bind to DNA to increase or decrease transcription. d.They modify newly transcribed mRNA sequences.13. Two transcription factors, A and B, are required to bind an enhancer, E, in order for Gene X to be transcribed (see diagram) 00 Gene X Let a and b represent recessive amorphic alleles of the transcription factors and E represent a deletion of the enhancer. Assuming Gene X IS haplosufficient, what phenotype will the following individuals have? Individual 1: Ala B/b E/E Individual 2: A/A B/B E/E- a. Individual 1: Wildtype; Individual 2: Wildtype b. Individual 1: Mutant; Individual 2: Wildtype c. Individual 1: Wildtype; Individual 2: Mutant d. Individual 1: Mutant; Individual 2: Mutant