1 Which of the following is/are true for sickle-cell anemia?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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1 Which of the following is/are true for sickle-cell anemia?

I. It results from a point mutation on the beta sub-unit which results to the amino acid substitution of V with E.

II. The sickle-shaped RBC's are vaso-occluded in the capillaries resulting to damage in various internal organs.

III. Hemoglobin precipitates when deoxygenated, resulting to the distortion in the shape of the thrombocytes.

Select the correct response:

  • l and Ill
  • I, II, and Ill
  • I only
  • Ill only
  • ll and Ill
  • Il only
  • I and Il
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