Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Help on number 2

Do not understand what needs to occur at 25mmhg and 50 mmhg with a pressure/volume graph and laplace law

A pregnant woman in preterm labor delivered a premature infant at only 27 weeks of gestation (normal
pregnancy term is 37-42 weeks). After the delivery, the infant began to grunt and showed signs of hypoxia
despite oxygen supplementation (inspiring pure oxygen). The baby was intubated and a synthetic surfactant
was given.
1) Since lung tissue is elastic and tends to decrease its volume; there is always a negative intrapleural pressure
of approximately 5 cm H₂O. Assuming the alveolus with a radius of 0.2 mm. What is the surface tension
require to prevent alveolar collapse in the baby?
2) As the baby starts normal respiration, the volume of the alveolus changes between (100-40%) fully-filled to
partially-filled. Plot how the changes in alveolus volume would affect the surface tension.
3) Is there any chance of alveolus collapse at higher tidal volumes? Why?
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Transcribed Image Text:A pregnant woman in preterm labor delivered a premature infant at only 27 weeks of gestation (normal pregnancy term is 37-42 weeks). After the delivery, the infant began to grunt and showed signs of hypoxia despite oxygen supplementation (inspiring pure oxygen). The baby was intubated and a synthetic surfactant was given. 1) Since lung tissue is elastic and tends to decrease its volume; there is always a negative intrapleural pressure of approximately 5 cm H₂O. Assuming the alveolus with a radius of 0.2 mm. What is the surface tension require to prevent alveolar collapse in the baby? 2) As the baby starts normal respiration, the volume of the alveolus changes between (100-40%) fully-filled to partially-filled. Plot how the changes in alveolus volume would affect the surface tension. 3) Is there any chance of alveolus collapse at higher tidal volumes? Why?
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