1) Predict the Major product(s) for the following reaction (from pages 178-192 in the notes). COUNT your carbons! (5 pts.) Show the correct stereochemistry when needed!! excess HCI

Please follow directions

Predict the Major product(s) for the following reactions. (10 pts total) Show the correct stereochemistry when needed!! mechanism: SH substitution CI

34. Draw the major organic product(s) for the following reactions; (*) must include correct stereochemistry; double-dagger (+) must show two products. HBr (a)* Br HBr Br (b) + (1.00 equiv.) Br Br HBr (c)* HCI (d) 48% wt. HBr 37% wt. HCI HEAT OH [H2SO]/ H20 (g) OCH3 [H2SO,]/A CH,OH (excess) (h) [H,SO,1/H20 OH (i)* [H2SO,] / H,0 OH 13

Q8: Rank the following compounds in order of increasing reactivity in a nucleophilic substitution reaction with CN as the nucleophile. Br A B NH2 LL F C D OH CI LLI E Q9: Complete the missing entities for following reactions (e.g., major product(s), reactants, and/or solvents) for the SN2 reactions to occur efficiently. Include curved-arrow mechanism for reactions a) to d). a) H "Cl D + -OCH 3 Page 3 of 5

4. Regioselectivity Draw the major product formed for each reaction. Assume the reactions are irreversible. Include stereochemistry when products contain stereocenter(s). (a) Draw only the substitution product. Both elimination and substitution occur here. Hac Br CH₂OH (c) (b) CH3 CH3 Br H NaOCH3 80 °C 1 equiv CH3Li then

Identify the major product of the reaction of an alkene shown below. ||| 1. Hg(OAc)2, H2O 2. NaBH4, NaOH ....... ОН || IV ОН о, ОН

Draw the product of reaction

My Home OWLV2 | Online teaching and lear X G D /ilrn/takeAssignment/takeCovalentActivity.do?locator=assignment-take IReviaw Toples Draw structures for the carbonyl electrophile and enolate nucleophile that react to give the enone below. You do not have to consider stereochemistry. Draw the enolate ion in its carbanion form. Draw one structure per sketcher. Add additional sketchers using the drop-down menu in the bottom right comer. Separate multiple reactants using the + sign from the drop-down menu. aste [F ChemDoode Submit Anewer Retry Entro Group 8 more group attempts remaining

Draw a structural formula for the major organic product of the reaction shown below. & CH₂ (oran CH3CH₂O -CuLi 2 ether You do not have to consider stereochemistry. Sn [F ? ChemDoodle H3O +