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What is the Fluid Mosaic Model of the Cell Membrane?

Answer – The fluid mosaic model characterizes the cell membrane as a dynamic structure primarily comprising a phospholipid bilayer and embedded proteins in a mosaic-like appearance.

Explanation: 

S.J. Singer and Garth L. Nicolson first proposed this model in 1972. The cell membrane is composed of a phospholipid bilayer with a thickness of approximately 510 nanometers (nm). It is a double layer of lipid molecules with hydrophilic (water-attracting) heads facing outward and hydrophobic (water-repelling) tails facing inward, creating a barrier for substances traveling in and outside of a cell. Thus, the model provides selective permeability (semi-permeability) and flexibility to a cell. 

Within this bilayer are proteins, glycoproteins, glycolipids, and sterols embedded, thus forming a mosaic, hence, the name of the model is the “fluid mosaic model.” These proteins are integral to the membrane’s role in cellular communication and regulation.

The fluid mosaic model of a cell membrane with the phospholipid bilayer and proteins embedded in it
The fluid mosaic model of the cell membrane describes its structure and function.
Image credit: Laboratoires Servier / Wikimedia Commons (licensed under CC BY-SA 3.0)


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