On Tuesday, January 30th, Matt Wachowiak from Yale University gave a seminar on functional imaging of the olfactory bulb in mice. He uses a fluorescent calcium-sensitive dye to label the receptor neurons in the nose; the dye is then transported to the terminals of those neurons in the olfactory bulb. All of the receptor neurons that express receptors for a certain type of odor molecule send their axons to the same localized structure within the olfactory bulb, called a glomerulus. By removing the skin and bone above the olfactory bulb, he can use a sensitive camera to record real-time changes in fluorescence in particular glomeruli that correspond to activation of different receptor neuron types in response to different odors. Dr. Wachowiak began these studies in turtles, …show more content…
Although an individual glomerulus may be activated by several odors, the relative levels of activation of several glomeruli differ between odorants. As the concentration of the odorant increases, more glomeruli are recruited to respond; however, the relative pattern of activation is usually maintained for each odorant. Dr. Wachowiak also showed that there is a topographical map in the olfactory bulb such that odorants belonging to a certain class of molecules tend to activate glomeruli in the same area of the bulb, and this map is consistent across animals. Thus, it is possible to study the response to many odor molecules in a large number of animals and collapse the data across subjects to obtain more statistical power. In conclusion, this is an interesting technique that can be used to understand the detailed mechanisms of first-order olfactory perception in live animals. Dr. Wachowiak hopes to continue this research by conducting psychophysical experiments to determine how well the mice discriminate between odors, using genetically encoded probes of neural activity to selectively image certain populations of glomeruli, and studying further steps of processing within the
These two small branches run caudally and then change their direction immediately toward the olfactory sulcus (in a recurrent way) accompanying both the olfactory tract and the olfactory bulb, most likely corresponding to the persistent primitive olfactory artery (PPOA)(fig. ). On the right side this vessel is more prominent (fig 1, fig 2). At the confluence of the olfactory tract and olfactory bulb, resembles a hairpin and then gives two branches, the anterior branch runs in the olfactory sulcus distal to the olfactory bulb and distributes on the frontal pole on the area corresponding to the fronto-polar artery normaly a branch of the anterior cerebral artery. The posterior branch runs laterally and distributes on the orbital surface of frontal lobe. Before its division the right ppoa supplies the ipsilateral straight girus with multiples
The Wampanoag' is a Native American individuals in North America. They were a free alliance comprised of a few tribes. Numerous Wampanoag individuals today are selected in two governmentally perceived tribes, the Mashpee Wampanoag Tribe and the Wampanoag Tribe of Gay Head, or four state-perceived tribes in Massachusetts. In the start of the seventeenth century, at the season of first contact with the English, the Wampanoag lived in southeastern Massachusetts and Rhode Island, a domain that incorporated present-day Martha's Vineyard and Nantucket islands. Their populace numbered in the thousands because of the extravagance of nature and their development of corn, beans and squash. Three thousand Wampanoag lived on Martha's Vineyard alone.
These receptors record on a extensive form of sensory modalities including changes in temperature, stress, touch, sound, mild, style, odor, physique and limb actions, and even blood pressure and chemistry. Scientists have recognized for nearly a hundred thirty years that distinct afferent nerve fibers of the peripheral nervous procedure are in contact with specialized non neural receptive buildings which realize and transmit sensory knowledge from the periphery to the Central Nervous System. The non neural receptive structure in conjunction with its afferent nerve fiber is mainly called a
Activators of Adenylate Cyclase would cause production of cAMP, which is a second messenger. This would amplify the signal and increase the extent of the scent.
We have all have those moments throughout life that are exciting with learning about the global society.
Smells connection to emotion was also discussed, it turned out to be molecules with receptor signals capable of triggering memory through the olfactory part of our brain and the hippocampus, the site of memory
Wupatki is not necessarily located where people would typically think a large group of people would live, however, this area became the home to almost 2000 people during the 11th to 13th centuries. The area is harsh in landscape and very dry. Natural vegetation is limited in this area, however, not too far to the south you will start to climb in elevation and with it you will find yourselves in the pines. The people that lived there are ancient Singua ancestors called Pueblo. Wupatki is a large structure that sits on a ridge of a plateau overlooking much of the surrounding landscape. You can see for miles and miles in this location, which would have been a perfect location for defense reasons. It also would have been the perfect location
5. What is the function of odor? The function of the odor is to attract certain mammals and insects.
On March 26, 2016, the American Indian Student Association held a Powwow at the University of Oklahoma at the Lloyd Noble Center. This event was the 102nd of its kind at the university. It started at 2pm and continued on until midnight. I arrived after the Gourd Dance and food around 6:30 pm.
Ani Lui explained the importance of smell and how we can use it to fix are problems in life. “Nothing is more memorable than a smell. One scent can be unexpected, momentary, and fleeting, yet conjure up a childhood summer beside a lake in the mountains” (Diane Ackerman).On Ted Talk, Lui talked about how smell can be a huge resource to our everyday life.The show was called “Smelfes, and other experiments in synthetic biology”. She showed pictures of fruits like strawberries that could grow its own fruit. Ani Lui is from EIT lab, a designer. She sorts out science fiction and science fact. At their lab, they study artificial life and objects. Back in the 19-century women would put an apple under there underarm. If the man ate the apple that meant
A third preteen has died in an alleged suicide pact discovered last summer, and it has resulted in a "mental crisis" among dozens of other children. Consequently, the Wapekeka First Nation declared a state of emergency as the community grapples with the disturbing adolescence deaths.
Decreased interest in olfaction may be related to early work which contrasted varying levels of olfactory abilities among animals, highlighting primates as deficient in this sense. In Turner’s 1891 paper The Convolutions of the Brain, he proposed a classification of Mammalia into three groups 1) Anasmotics, where the organs of smell are absent and included dolphins and whales, 2) Macrosmatics, defined by animals with a highly developed sense of smell and included ungulates, carnivores and most mammals, and 3) Microsmatics where the sense of smell is “feeble” as in pinnipeds, some whales, and apes and man. This idea of apes and humans, indeed, primates in general having a poor sense of smell was corroborated by Negus in 1958 and Le
“ ‘They’re afraid of us. They want to capture you and learn more about us ----------- that’s why there’s the large reward. It isn’t just a question of the true image ---------- though that’s the way they’re making it appear what they’re seen is that we could be a real danger to them.’ “ (132).
Smell, on the other hand, is the sense that comes from odor molecules attaching to the olfactory nerve. Air carries the odor into the nose. Then odor contacts the olfactory nerves at the top of the nasal passages. The the olfactory nerves send a signal to the olfactory bulb of the brain, and the nerve sends a signal to the front of the brain. The forebrain translates the signals of the odor into a specific smell (Swindle, Mark).
Nature Neuroscience Journal published a research that shows a mouse trained to become scared of cherry blossoms smell before they are allowed to breed, produce offspring that show the same fearful response towards the cherry blossom although they only encounter it for the first time.