Introduction
Disease has existed for as long as life has, but even the most primitive form of vaccination – variolation – was only invented around 1000 AD by the Chinese to cure smallpox (NHS, 2014). Since then, of course, vaccination has advanced tremendously and many diseases are now no longer a danger because of it. However there are still hundreds of diseases that cause trouble in the world despite vaccinations, and some diseases that have no vaccinations at all. Rabies (lyssavirus) is a severe viral disease that affects the nervous system and is deadly if not treated. Fortunately, a vaccine does exist, created by Louis Pasteur in the 1880s (NHS, 2014) and improved in the 1960s, but still today over 55 000 people die of this disease
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The infected person could feel symptoms less than a week or over a year later (WHO, 2014), in the most extreme cases. Once the incubation period is over and enough of the virus has been replicated, it uses neurons in the peripheral nervous system and exploits axonal transport mechanisms so that it can eventually invade the central nervous system and reach its target – the brain (Gluska, S. 2014). Once in the central nervous system rabies causes acute brain inflammation, causing psychosis and extreme aggression (n.p. 2014). It then travels back through the peripheral nervous system, eventually concentrating in the salivary glands to be transmitted to the next victim. Because of the concentration in these glands, most victims suffer excruciating pain upon swallowing and develop a fear of liquids (Health Central, 2014).
The vaccine
Rabies is lethal nearly 100% of the time if left untreated, and in the past it was extremely dangerous, having been documented as early as 2300 BC in Babylonia (A Rabies-Free World Inc, 2010). Fortunately in the 1880s Louis Pasteur created the first rabies vaccine. The vaccine was originally harvested from infected rabbits, but in 1967 the human diploid cell rabies vaccine was started. Unlike many vaccines, the rabies vaccine is usually administered post-exposure to prevent the development of clinical rabies after introduction of the virus, but it can also be administered pre-exposure if the person is at a high risk of contracting the
Vaccinations have been actively used for over 200 years now and have been effective for over 200 years as well. Western medicine’s introduction to the practice is said to have occurred within the eighteenth century, when a traveling British aristocrat, Lady Mary Wortley Montagu, reported her observations of Turkish children being injected with pus from smallpox victims. Although this practice seemed quite harsh, most of these children would contract only a mild version of the illness. In return, these recipients would retain a lifelong immunity to this terrible disease (World of Microbiology & Immunology). Similarly, in the United States, a Puritan minister by the name of Cotton Mather learned about inoculation from his African slave, Onesimus. Onesimus claimed that he was inoculated with smallpox pus and never caught the tragic disease (Williams). This type of medicinal treatment was initially rejected by most Western practitioners. They felt it was a dangerous and barbarous practice, but vaccination gained a tremendous amount of support at the turn of the nineteenth century when English physician Edward Jenner created a new smallpox vaccine derived from the relatively mild cowpox virus (Riedel). There’s no doubt that history has shown the positive outcomes of immunization and continued to show them as technology and medicine progressed.
Rabies is spread through animals bites of an infected animal. Symptoms involve fever, headache nausea, etc. The animals that can trasmit rabies are cats, dogs, wolves, bats, and more. The reason why rabies is called hydrophobia, “fear of water”, due to how in one of the symptons of rabies, a person will not be able to swallow liquids which causes
The Patriot Act can also cause many inconveniences in TSA, which stands for Transportation Security Administration. “TSA is an agency that was created in 2001 agency to safeguard United States transportation systems and insure safe air travel,” (Computing, 1). They give airport security the right to search people and their belongings through screenings and
The cause of his death couldn’t be rabies. “Dr. Benitez admits the primary weakness of his theory- lack of evidence of a bite or a scratch.” (Benedetto 189). Poe had no bites or scratches on him when he died. “Guiltless was the pet Caterina, who, uninfected and showing no signs of rabies” (Benedetto 189). That is the only animal he could’ve gotten “rabies” from. And his cat didn’t have it, Caterina died of
For one to understand the risk behind each vaccination is a very serious matter, identical to other procedures there are calculated risks involved with each vaccine. For example about one in every 520 thousand people will contract the polio disease 7- 30 days prior to receiving the polio oral vaccine (1). This is because the vaccine contains a very small amount of live attenuated strain of bacteria, and in very rare cases can cause the disease that is in attempt to be prevented to be transmitted to the patient. Other side effects include pallor or erythema in site of injection (which only means pale or redness of skins), also one is at risk for anaphylaxis shortly after receiving certain kinds of vaccines, but the most common side effects include rashes and bumps (1). While a more
Mandatory vaccination continues to be a contentious subject in the United States, even though extensive evidence proves inoculation prevents certain diseases. According to A. Plotkin & L. Plotkin (2011), the evolution of the first vaccine commenced in the 1700’s when a physician named Edwards Jenner discovered that cowpox protected individuals from one of the deadliest diseases termed smallpox. The precise virus Jenner used is unclear; however, it was espoused in the extermination of smallpox worldwide. The researchers further explained, the unearthing of the subsequent vaccine known as chicken cholera occurred approximately 80 years later by Louise Pasteur. Ever since, copious vaccines such as rabies, yellow fever, varicella, pneumococcal, mumps and recently HPV have been introduced.
The theme of the movie Osmosis Jones follows the monomyth stages. The monomyth by Joseph Campbell is when a hero goes on a dangerous adventure, and in a crisis wins a victory, and returns home with knowledge, treasure, or love. It is when a hero starts out in their normal daily lives to a dangerous adventure that will change them either physically or mentally. Jones was a regular white blood cell cop that made lots of mistakes, but he wanted to change his reputation by curing Franks’ illness. The hero when in a crisis like Jones wins the victory by either strength, bravery, or courage. The hero then returns with knowledge of two worlds. All heroes follow the monomyth stages and have themes that ordinary
Throughout history, vaccinations have been used to help the prevention of infectious diseases; some of which can produce serious illnesses, crippling disabilities, and ultimately be the cause of death. There is evidence of ancient culture’s attempting to treat transmittable diseases with various forms of inoculations. Developments in the research of vaccinations increased during the mid-twentieth century because of the established of more advanced laboratories, improved equipment, and new innovations. The progression of medicine during history has helped further the development of research into vaccinations. Several cultural, ethical, and religious issues have resulted from the development and use of vaccinations in our society. The topic of vaccinations has caused a strong debate amongst our culture about the safety and danger of treating infectious diseases with such methods.
Vaccines have been used to prevent diseases for centuries, and have saved countless lives of children and adults. The smallpox vaccine was invented as early as 1796, and since then the use of vaccines has continued to protect us from countless life threatening diseases such as polio, measles, and pertussis. The Center for Disease Control and Prevention (2010) assures that vaccines are extensively tested by scientist to make sure they are effective and safe, and must receive the approval of the Food and Drug Administration before being used. “Perhaps the greatest success story in public health is the reduction of infectious diseases due to the use of vaccines” (CDC, 2010). Routine immunization has eliminated smallpox from the globe and
Measles. Polio. Smallpox. The flu. Imagine the world when vaccines were yet to be created. There was a time when people lived in fear of dreadful diseases. Thanks to the introduction of vaccines, many of those devastating diseases have been nearly or completely wiped out. Despite these results, for some people, the question remains: should we vaccinate? Today, I will be discussing the development of the first vaccine, global benefits, and the anti-vaccine movement.
Rabies had been known about since 2000 B.C. but technology was obviously not advanced enough to try and do anything about the spread of the virus. In the year 1885, France and Belgium had become plagued with more and more cases of the rabies that the fear had soon began to become a very reasonable fear for people to have. This gave Louis Pasteur ample reason to research more about the virus.
Rabies is a highly infectious viral disease that can easily ruin and eventually end the lives of both humans and animals alike. Rabies comes in two forms for animals. It comes in the form of paralytic rabies, which is the kind that puts you in paralysis right from the beginning, skipping the symptoms of agitation and excitability. Rabies also appears in the form of furious rabies, which is completely different in the way that it makes the victim restless, vicious and agitated. When humans get rabies, their symptoms start out with simple headaches and fevers and later progresses to terrible things such as becoming hydrophobic because of painful throat spasms and paralysis. A definite diagnosis of rabies needs lab analysis of
Our current society is surrounded by the debatable usage of vaccines and its importance around the world. Since the introduction of immunizations, many diseases have been decreased and even eradicated from humanity. Even though this is true, serious side effects along with lifelong illnesses follow the temporary cure of viruses. A vaccine is a substance that delivers immunity against viruses and is used to stimulate the construction of antibodies. Vaccines are prepared from the disease itself treated to perform as an antigen without inducing the disease (Vaccines). These inoculations are used worldwide and various unknown infections have been speculated as the originations for them. Vaccines were originated as an alternative to cure viruses among people but the harmful symptoms, unknown links to incurable
Because rabies is transmitted through saliva, the disease is usually brought about into the body by a bite of an animal already infected with the lyssa virus (rabies). Rabies then deposits itself into the tissue of the host (person/animal who has the virus in them), infecting the host and later multiplying. From there, the virus travels from the nerves to the muscles, then to the brain and spinal cord (Easmon paragraphs 8-9). At this point, the virus is multiplying rapidly and soon the brain is extremely affected, which causes it to malfunction and the part of the brain that controls breathing shuts down (Buncombe paragraph 8).
Fingerprints are impressions left by friction ridges present on the skin of fingertips [Champod & Lennard 2004; Mozayani & Noziglia 2006]. Each friction ridge contains pores that are attached to sweat glands under the skin. These ridges are formed in the dermal papillae, the uppermost part of the dermal layer, and can be found on the soles of the feet and palms of the hand (Figure 1.1) [Champod & Lennard 2004; Mozayani & Noziglia 2006]. The ridge patterns can be physically examined to determine points of identification when comparing a sample fingerprint to an exemplar. A detailed description of these patterns is provided by Lee and Harris (2006).