Type 1 Diabetes Mellitus Research Paper

Diabetes Mellitus is a growing issue for health care providers internationally. The World Health organization estimated in 2013 there were 347 Million diabetics worldwide, predicting that Diabetes will be the 7th leading cause of death by 2030 (WHO, 2013). In both type 1 and type 2 diabetes Mellitus, factors such as poor compliance with diet and medication, infection, acute medical or surgical illness or trauma can lead to poor glycaemic control, precipitating a hyperglycaemic emergency such as Diabetic Ketoacidosis (DKA) (Scobie & Samaras, 2009). In Type 2 Diabetes, another equally dangerous

Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the

Type 1 diabetes is an autoimmune disorder, in which the pancreas does not produce insulin. It usually begins in childhood or adolescence. In Type 1 diabetes, the body’s immune system destroys beta cells in the pancreas that produce insulin. Insulin is a hormone that converts sugar, starches, and food into energy. Without insulin, blood glucose levels become too high, which is known as hyperglycemia. To prevent hyperglycemia, people with Type 1 diabetes must take insulin daily to survive. Genetic and environmental factors affect the onset of Type 1 diabetes. [1] According to the American Diabetes Association, a predisposition to Type 1 diabetes is

Type one diabetes is an autoimmune disease. When a person has type one diabetes the immune system attacks the beta cells that produce insulin. When enough cells are destroyed the body doesn’t produce enough, or any insulin. Without insulin your cells do not absorb the glucose that accumulates in the blood stream. In addition to a spike in the blood sugar, the body is not storing the glucose as glycogen as a reserve.

Type 1 Diabetes Pathophysiology: Autoimmune- Anti islet antibodies attack through Lymphocyte infiltration and destruction of the insulin secreting beta cells of the langerhans within the pancreas.

Insulin is a hormone that is needed to allow sugar (glucose) to enter cells to produce energy. A more common form of diabetes is the type 2 diabetes. This condition develops in an individual when the body becomes resistant to insulin or doesn't produce the required amount of insulin. Type 1 DM can occur at any age. It is commonly found in children but this disease is also common among adults. Various factors contribute to an individual being diagnosed with type 1 diabetes, which may vary from genetics, exposure to certain viruses, lifestyle choices etc. Those with type 1 DM usually are not obese and initially show symptoms of diabetic ketoacidosis (DKA). These patients are dependent on exogenous insulin to counter low levels of

During 2008-2009, 18,436 people younger than twenty years of age were diagnosed with type one diabetes. Because of diabetes, 18,436 people had to completely change their way of life for a disease that is currently incurable. Out of the U.S population, 9.3%, or 29.1 million people, currently live with diabetes. Each year, 40,000 new cases of diabetes are diagnosed in the U.S. Between 2001 and 2009, the number of cases of type one diabetes in people younger than twenty years of age increased by 21%. The annual healthcare costs associated with type one diabetes totals $14 billion. Diabetes is a life-altering disease whose affects can be seen at all stages of life. If it is not well managed, diabetes can result in blindness, nerve damage, loss of limbs, cardiovascular problems, and death.

Diabetic ketoacidosis is an event which occurs when there is not enough insulin in the body to utilize sufficient amount of glucose needed to provide cells with energy; body then starts to use fatty acids as a fuel, which are converted to ketones in the liver. In healthy people who do not have diabetes, ketone bodies are produced in normal quantities and then successfully used by tissues as energy supply. This state is known as dietary ketosis and it is completely normal and may even provide health benefits. But in those who have diabetes, ketones are produced in enormous quantities and aren't used in full by cells, so they start to build up in the blood. Acids 3-hydroxybutyric acid and acetoacetic acid are produced rapidly causing decrease in buffering capacity of the blood and eventually depleting buffering systems (Manninen, 2004).

Type 1 diabetes (T1D) is the autoimmune destruction of insulin-producing-β-cells located in the pancreas, specifically in the islets of Langerhans, responsible for regulating blood glucose levels in the blood. Insulin is a hormone which when released, signals the live, muscle and fat cells to take in glucose to be used as energy. If the body has sufficient energy, then the liver can store the glucose through the passage of insulin into glycogen. Glucagon, the antagonistic hormone to insulin produced by Alpha cells in the pancreas, is released when the blood sugar levels are too low and causes the liver to convert the stored glycogen into glucose. The difference between type1 and type 2 diabetes is that T2D is when the body does not effectively respond to

Type 1 diabetes is a disease caused when your immune system destroys the cells in your pancreas that create insulin. This leaves your body without enough insulin to function normally. A very small amount of people that have diabetes have this type. Normally when people have this type of diabetes they are diagnosed as children. When you have type 1 diabetes your body will break down the foods, such as starches and sugars, and turns them into glucose. This glucose, which is a sugar, is then used for energy. In order to get glucose from the bloodstream into your cells your body need the hormone of insulin. Testing your blood sugar is most likely something that you will have to do often if you are diagnosed with diabetes. This can help you to

This disease was once known as the juvenile diabetes or insulin-dependent. This is a condition where the pancreas produces hardly any insulin, sometimes not even any. There is not an exact cause for type 1 diabetes. What happens is the body's immune system mistakenly destroys the insulin producing in the pancreas. They have found that genetics may have a part in this, or even certain environmental factors. For example would be viruses.

Diabetes is a serious and complex condition that effects the whole body and the life of the person who is diagnosed. A person suffering from diabetes is unable to maintain healthy blood glucose levels. This is because the body does not produce enough insulin, a hormone that is needed to allow glucose to be converted to energy. Being diagnosed with diabetes means having to manage your life style and eating plan. If the body is not treated with the right care, the life of the effected person may be severely reduced. There are two main types of diabetes, type one and type two. Type one diabetes is a condition that usually onsets at an early age and cannot be prevented. Type two diabetes is usually discovered in adulthood, but there is an increasing

It is an autoimmune disease caused by the immune system mistakenly turning on itself, and causing the pancreas to discontinue and no longer create insulin. Ultimately, the cells, which actually make insulin, have been destroyed by the bodies’ own immune system, thus resulting in imbalances and unordinary levels of glucose within the blood stream. This is unfortunate to people whom posses’ type 1 diabetes, as because they cannot produce insulin, they require lifelong insulin injections in order to survive and must also be constantly prepared for potential hypoglycaemic (low blood sugar) and hyperglycaemic (high blood sugar)

Type 1 diabetes is an autoimmune disease that destroys beta cells, beta cells produce insulin in the the pancreas. When beta cells are destroyed It leads to lack of insulin, insulin lowers blood sugar (glucose). When immune system cells are seen it can also cause a viral infection.

Special cells in the pancreas produce a hormone called insulin to regulate metabolism. When this hormone is not present glucose cannot enter body cells and blood glucose levels rise. Hyperglycemia may result from this situation. This process is the development of diabetes mellitus. Type 1 diabetes, formerly called juvenile diabetes or insulin dependent diabetes mellitus, has two forms; immune-mediated and idiopathic. Type 1 diabetes accounts for 5-10% of cases in the United States. Research has shown that there is an inherited tendency for developing the disease; it may be triggered by environmental factors (Rosdahl & Kowalski, 2008). It also has an autoimmune component since antibodies to insulin and islet cells are present at the time of