Every 25 seconds a person dies from tuberculosis. This equates to approximately 1.3 million people every year (Global Alliance for TB Drug Development, 2014). Tuberculosis, or more commonly known as TB, is more prominent in developing countries with 80% of Asian and African countries testing positive for tuberculosis (Abbas AK, 2007). India currently has the most cases of TB in the world (World Health Organization, 2009). There are a few types of TB such as common, partial drug resistant and drug resistant. The disease that will be focused on today is common tuberculosis.
Tuberculosis is as old as mankind. It was first officially recognised by Hippocrates who described the symptoms of the disease as coughing up blood and weight loss that eventually led to death. In the 16th century a theory was proposed that the disease was transmitted via microorganisms. This was not proven until 1882. In the 1880’s, the chosen way of curing tuberculosis was for the patients to receive clear air, a balanced diet and plenty of rest. This was used not only to treat the patients but to also isolate them. During the 19th century, the spread of the disease slowed as living conditions and hygiene improved. In the 20th century a vaccination was developed as well as antibiotics. This resulted in the disease declining dramatically. It wasn’t until the 1980’s that the disease reappeared again due to the aids epidemic. Due to the aids sufferers having a weaker immune system, they were more
While tuberculosis was never completely eliminated, there was a significant drop in cases and death rates, as a result of the BCG vaccine and new anti-tubercular drugs in the 1950’s.
Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8
Hi my name is Tyree Coleman and today I will inform you about a world known disease called Tuberculosis but most commonly known as TB. Tuberculosis is a infectious disease that mainly affects your lungs. Like many other diseases Tuberculosis is airborne is very easy to contract. This disease was first discovered in March 24, 1882 by a German physician and scientist named Robert Koch. Koch simply found traces of mycobacterium tuberculosis in cows, which is the bacterium that causes Tuberculosis. Many people are at risk of getting TB but may not even know it because of how quickly the disease can spread and not knowing enough information about it or not getting tested. The most common way you can get Tuberculosis is by being in constant
Tuberculosis is considered to be another surfacing disease. According to the Institute of Medicine, they believe the sole reason of the resurgence of tuberculosis is the increase in immunosuppressed populations. In industrialized countries, peoples
Tuberculosis has been part of human history for a long time but how long is a long time? Recent research using genetic data has allowed us to know that the tuberculosis progenitor has been on this planet for about 3 million years affecting even our earlier ancestors (Gutierrez et al, 2005). Additionally this research showed that the bacilli from tuberculosis are capable of mixing sections of their genome with other strains and giving the pathogen a composite assembly, which resulted from ancient horizontal exchanges before its clonal expansion. This quality provided tuberculosis a big advantage that even now a days allows the organism to evade, adapt and create resistance to treatments that were once successful. In order to fix current and
Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.
According to the World Health Organization, tuberculosis (TB) is the number two killer worldwide due to a single infectious agent (WHO, 2017). In 2015, 10.4 million new cases have been identified and 1.8 million people have died from this disease (WHO, 2017). TB is caused by the bacteria Mycobacterium TB, and the majority of TB deaths occur in low and middle-income countries. This disease is curable and preventable, but the lack of access to proper healthcare and medication administration makes it a concern for the most of the world’s population. TB is an airborne disease that can transmit when an infected person coughs, sneezes, spits, laughs, or talks. The majority of TB cases can be cured when the right medications are available and
Among many misconceptions, tuberculosis is not a disease of the past. Tuberculosis remains a public health issue. It is estimated that one-third of the total world population is infected by tuberculosis (TB). The American lung association (2013) states, in 2011 alone there were nearly 9,000,000 new diagnosed cases of tuberculosis around the world and an estimated 1.4 million deaths because of this disease. In the United States, TB is not as common (but still a problem). In 2011, only 10,500 people reported having TB (Trends in Tuberculosis Morbidity and
Tuberculosis has long been a disease that the human culture has been dealing with which entails significant morbidity and mortality worldwide. With dealing with such a horrific disease over the years, discoveries and evolution on the appropriate ways to contain, diagnose, and challengingly treat the disease has changed. One of the most concerning complications of this worldwide public health issue is the ability for it to quickly spread in high populated areas while becoming ever more resistant to forms of treatment not available in all locations around the world. This is a serious public
As the time progresses, the world population increasing exponentially which results in a higher spread of diseases. Even though it might seem like increasing population has nothing to do with Tuberculosis and it's reemergence in the 21st century, however, there are links that do provide some clue on a possible threat to the global health.
Over 95% of all TB cases and 98% of its deaths occur in middle and lower countries. These high numbers are caused by poor public health systems, high poverty levels and rapidly growing HIV/AIDS incidents in this region (Sulis et al., 2014)..
Tuberculosis is among the fatal diseases that are spread through the air. It’s contagious, meaning that it spreads from one infected individual to another, and at times it spreads very fast. In addition to being contagious, the disease is an opportunist infection as it takes advantage of those with weak defense mechanism, and especially the ones with terminal diseases like HIV and AIDS. Tuberculosis is therefore among the major concerns for the World Health Organization due to its contagious nature (World Health Organization 1).
Tuberculosis has always been an infection closely linked to poverty and is second only to HIV/AIDS as the greatest killer worldwide due to a single infectious agent. Over ninety five percent of tuberculosis deaths occur in
The study findings could be proved useful for the development of future methods of prevention and treatment of tuberculosis.
In 2011, WHO estimated 12 million prevalent cases of tuberculosis worldwide, of which about 630 000 (roughly 5%) were MDR tuberculosis. The highest caseloads of MDR tuberculosis were reported in India, China, Russia, and South Africa, which accounted for more than 60% of cases worldwide. India and China have the highest number of MDR tuberculosis cases worldwide. Tuberculosis has now been made a notifiable disease in India. Drug resistance surveys in several states have indicated that the prevalence of MDR TB in India is 2–3 percent among new cases and 12-17 percent among reinfection cases. According to drug