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The Scope Of Coronary Artery Disease Detected By Coronary Computed Tomography Angiography

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Study Reference Journal Study Design Study Population (n) Findings Framework Research Priority 1: Define the scope of Overdiagnosis and Overtreatment in Medicine Framework Research Priority 2: Identify the most important drivers of overuse Framework Research Priority 3: Measure the Impact of Overuse Framework Research Priority 4: Understand the Impact of Choosing Wisely and other initiatives on clinical practice and patient outcomes
Lee et al. (2016) [18]

Academic Radiology Commentary N/A Highlighted the methodological limitations of overdiagnosis research (i.e., counterfactual incidence, insufficient follow-up time, and trial design limitations). Modeling could better predict outcomes to inform recommendations and policies. X
Schmidt et al. (2016) [19]

Journal of American Medical Association Internal Medicine Case study 60 year old male patient (1) Explored the Overdiagnosis of Coronary Artery Disease Detected by Coronary Computed Tomography Angiography. Authors expressed need to implement Choosing Wisely protocol for management of diagnosis. X X
Welch et al. (2016)
[20]
New England Journal Of Medicine Secondary data analysis Women 40 years or older with breast cancer (10% of US Population) While rate of detection of large tumors fell after the introduction of mammography as a screening technique, technique also resulted in increased detection of small tumors. Overdiagnosis of preliminary screening meant women were more likely to have breast cancer that was

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