The First Vaccine Developed Using Reverse Vaccinology

Neisseria meningitidis is a fastidious, aerobic, and encapsulated gram-negative diplococcus which infects humans via droplet transmission to and from mucosal surfaces in the nasopharyngeal region. Only humans can be infected with N. meningitidis and the disease manifests in children under two years of age and in young adults. N. meningitidis can be found as normal regional flora of the nasopharynx in some individuals, but when it causes infection leads to meningitis and occasionally septicaemia. The major symptoms of N. meningitidis infection include a stiff neck, high fever, photophobia, confusion, cephalgia and emesis. If the patient’s condition has worsened causing sepsis, they can present with a haemorrhagic rash which is indicative of

The aggressive treatment by the physician is necessary due to the immature immune system and the susceptibility to illness. Infections that are left

Medication assistant treatment also known as (MAT) is when a person has presented with an opioid addiction and have challenges stopping and/or abstaining from opioid use and they are prescribed either Methadone, Suboxone, or Vivitrol. Those who are in support for MAT is that this a better alternative to having individuals addicted to illicit substances. The other side to MAT is that this is way to keep individuals addicted to drugs, legally. I do not support MAT treatment as a form of long term treatment and not as the solution for opioid addiction. Serving as an Addiction Counselor and working with individuals who are addicted to opioids, I encounter many individuals who are or at one point utilized

During the early republic, the Roman state grew exponentially in both size and power. Though the Gauls sacked and burned Rome in 390 B.C., the Romans rebounded under the leadership of the military hero Camillus, eventually gaining control of the entire Italian peninsula by 264 B.C. Rome then fought a series of wars known as the Punic Wars with Carthage, a powerful city-state in northern Africa. The first two Punic Wars ended with Rome in full control of Sicily, the western Mediterranean and much of Spain. In the Third Punic War (149–146 B.C.), the Romans captured and destroyed the city of Carthage and sold its surviving inhabitants into slavery, making a section of northern Africa a Roman province. At the same time, Rome also spread its influence

In the recent years, vaccines have been in the center of many heated debates. The main one seems to be, are they causing other illnesses in the process of eliminating others? Many parents in the last four years have started opting their children out of the required vaccines right from birth. This has lead to a rise in infectious and contagious disease outbreaks all over the United States and the rest of the world.

It is especially common to a hospital patient with a present existence of different infection.

Meningitis is an infectious disease that can be found within the indigenous Australian community. Incidence and prevalence, when regarding an infectious agent or disease, utilizes measurements to determine new cases and existing cases of a disease process or infectious condition. Mathematical equations are utilized in order to determine and compare the survival or recovery, and duration of diseases ( Stanhope & Lancaster, 2011).The incidence and prevalence of meningitis in the indigenous Australian people, is higher in the rural areas then in the larger regions of Australia due to lack of access to vaccinations, and compliance with treatment. As noted via the meningococcal Australia INC

The discovery of vaccines prevented the spread of infectious diseases around the world. Vaccines control the spread of diseases such as measles, tuberculosis, smallpox, and the flu. In addition, vaccines increase the overall health of not only individuals, but of populations. Although these benefits prove effective on the world wide scale, the requirement of vaccinations of children to enter the public school system remains a current public health concern. Some argue that vaccines are dangerous for children and can lead to adverse effects. Others assert that the enforcement of requiring children to be vaccinated before entering schools protects the health of those attending school. These views create a challenge amongst parents who must

Africa has the highest incidence of meningococcal disease, tuberculosis, and malaria because of overcrowding in many villages. There is an area in sub-Saharan Africa called the Meningitis Belt that stretches from Senegal to Ethiopia with over 20,000 reported cases and 2,000 deaths every year (Healthgrades editorial staff, 2015). During the dry season in Africa, from December through June, meningitis epidemics occur with the three major areas infected being Burkina Faso, Nigeria, and Chad. The most recent outbreak of the meningococcal disease reported in the United States occurred as meningitis in the dorms at the University of California, Santa Barbara and Princeton University in New Jersey in December of 2013 (Doheny, 2013). When the outbreak occurred at these two universities it was caused from serotype B of the disease and resulted in one death. Since the current meningococcal vaccine does not cover the serotype B bacteria the FDA allowed the use of a special vaccine from New Zealand to treat the outbreaks (Burrell, 2015). One in five US teens have not had their first recommended dose of meningococcal vaccine and for those who have had the first dose of the vaccine,

As explained above, the best thing to do about this infection is to ensure that you prevent it. At least preventive measures will help to ensure that it is completely avoided.

Meningococcal Meningitis is the infection and inflammation of the meninges. Newborns and infants are at greatest risk for contracting bacterial meningitis with Neisseria meningitides being the typical pathogen in the majority of children age 2 months through 12 years (London, Ladewig, Ball, Bindler, & Cowen, 2011). There is a mortality rate of 10% for children who develop meningitis from this particular bacterium (Muller, 2013).

In the year 1911, a very well-known British novelist, poet, and playwright was born. His name was William Golding. Son of Alec Golding and Mildred Golding. Marlborough Grammar School was where William studied until he went to college. William published his first novel “Poems” in 1934 a year before he graduated. He graduated from Oxford in 1935, that day he received his B.A honors in English Literature. Golding got married to Ann Brookfield an Analytical Chemist in 1939. A year after their marriage their first child was born, named David Golding. His novel “Lord of the Flies” was published in 1954, which turned out to be the one that he became best known for. “Lord of the Flies” details the adventures British school boys had while they were

When children are born and for the first two years of their lives, they receive multiple shots and drops of vaccines. These vaccines protect them from getting diseases that were deadly and common in children many decades ago. Vaccine is one of the greatest achievement in medicine history. There were thousands of lives lost in the battle with some of the terrifying diseases like smallpox and polio. Now, after years of vaccine invention, vaccination spread in many countries which helped in eradicate several illnesses. In the United States, each family is required to show their children's immunization chart in order to get accepted in many educational institutes. Parents usually face the decision whether to vaccinate

Meningococcal disease is a large concern in the medical field because it is unbiased towards the patients it infects. There has been limited success in trying to eliminate this disease. Antibiotics play a role in helping to treat patients with bacterial meningitis, and steroids have been tested to help reduce risk factors. Prevention has also become a key issue because meningitis can only be spread through direct contact with infected body fluid. The best prevention is to maintain clean hygiene. Vaccines are another way of preventing disease. However, there are multiple serogroups of meningitis that makes creating a universal vaccine extremely difficult. So far, there have only been two

Diagnosis and treatment; Even diagnosis of the disease causing microbe is taught so as to give right drug and combat infection effectively. The identification of