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Takotsubo Cardiomyopathy Essay

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Epinephrine Induced Takotsubo Cardiomyopathy Background: Takotsubo cardiomyopathy also called as Stress-induced transient cardiomyopathy, apical ballooning syndrome, and broken heart syndrome was first reported in 1991 [1 in Japan, and accounts for 1.2% of acute coronary syndromes (ACS) that present with elevated cardiac biomarkers [1,2,3. The condition is often associated with acute medical illnesses, catastrophic life events, and intense physical or emotional stress [2, 3. Although the pathogenesis of stress-induced cardiomyopathy is not fully understood, the hypothesis includes catecholamine excess [16, coronary vasospasm, micro vascular dysfunction and dynamic mid cavity or left ventricular outflow tract obstruction. Postmenopausal women appear to be at a higher risk for developing the disease as about 80% of Takotsubo cardiomyopathy occurs in postmenopausal women [3]. …show more content…

The cardiomyopathy can be classified into a left ventricular (LV) apical ballooning variant (classic Takotsubo cardiomyopathy—most common), an inverted or reverse Takotsubo variant (basal akinesis with hyper dynamic apex), or a mid-ventricular Takotsubo variant [1. In this paper, we are presenting a case of epinephrine induced classic Takotsubo cardiomyopathy, which provides an evidence to support the role of epinephrine in the pathogenesis of this

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