Systemic Lupus Erythematosus: An Autoimmune Disease

Systemic Lupus Erythematosus is an autoimmune disease within the appearance of autoantibodies that fights against nuclear antigens within the body of a person who is living with SLE and the involvement of their organ systems, including the kidneys. The rigorous events that cause an onset of medical signs of SLE are not yet well understood. However, the researcher are usingnumerous mouse strains spontaneous and inducible lupus to find a cure because as of now there still is no cure for lupus.

Let alone the cause of this horrible disease. One of the most commonly suspected reasons for systemic lupus erythemotosus (SLE) is a very low iron count. Low iron has a veriaty of effects on the body including the feeling of being cold, low blood count (anemia), and impaired immune defiecency, ect.. Thus the low iron syptom seems to add up with lupus making doctor think that low iron can have a leading from in the disease.

Both medical journals provide similar information about SLE dealing with genetic influence, hormones, cytokines and similar treatment. Only difference is Mechanisms of Disease Systemic Lupus Erythematosus gives information about environmental influence and A Review of Systemic Lupus Erythematosus and Current Treatment Options journal has no evidence to support any environmental influence. It gives details about the new medication, Belimumab, which was approved by Food and Drug Administration (FDA). The results are small but significant beneficial with the blockade of B-lymphocyte stimulator with an anti-BLyS antibody (Tsokos, 2011). Another new treatment option is small molecule inhibitors of kinases such as Syk and CaMK4 that are showed in the immune cells of patients with SLE (Tsokos,

Lupus is a chronic inflammatory disease of unknown cause that can affect virtually any part of the body. The medical term for Lupus is Systemic Lupus Erythematosus or better known as SLE. With Lupus there is a malfunction in some of the cells of the immune system. "In Lupus, the body overreacts to an unknown stimulus and makes to many antibodies, or proteins directed against body tissue. Thus, Lupus is called an autoimmune disease. ”#

The movement and specifically the event I would have liked to take part, is what some have labeled “The Original American Protest.” The event I speak of, being the Boston Tea Party, and the movement itself was the start on the American Revolution. The American Revolution may be the most significant yet, overlooked movement in history. One reason I would have wanted to be present at the Tea Party, was because it was one of the first calculated protest against Great Britain, by the American people. By throwing the tea into the harbor the American people stated they were not going to accept the British taxing items they needed to import. Furthermore, it told the British they were not going to surrender to the British’s reign any longer. This

John Brown: Freedom Fighter or Terrorist? Terrorism is an act of violence that harms human lives, destroys infrastructure, causes mass destruction, assassination or kidnapping to affect a government, or intending to intimidate civilians or a population. An American abolitionist, John Brown, is a debatable subject on whether he was a freedom fighter or a terrorist. The unjustified event involving John Brown, including Pottawatomie Creek and Harpers Ferry, would characterize him as a terrorist by modern standards.

It is not rare for individuals with lupus to undergo muscle throbs and discomfort or have inflammation of certain muscle groups, which causes faintness and loss of intensity. More than 90 percent of people with lupus will encounter joint and/or muscle pain at some time during the path of their illness. In lupus, the immune system of the body raids its own cells and tissues. Precisely, the joints, skin, kidneys, lungs, heart, nervous system, and other organs of the body are affected. Lupus affects generally 10 times as many women as men. Most often, lupus develops in people 18 to 45 years old. (Lahita) Though lupus is most dominant among women, it also may affect men and children, as well as individuals of all ages. Lupus effects each person

The most commonly affected parts of the body are the joints, skin, lung, liver, kidney and heart. Systemic Lupus Erythematosus is more common in women than men especially woman from the age of 15-35. The cure for SLE is currently

Systematic lupus erythematosus (SLE) is a chronic, systemic, autoimmune disease. This condition causes the body to mistaken its own tissues and organs as foreign bodies and begins attacking them causing continuing inflammation and pain. (Huether & McCance, 2012) The cause of SLE still remains unknown, but it is possible that is inherited as a complex trait or caused by environmental stimuli. (S) Anyone is at risk for Lupus, but is more common among women than men and is more prevalent of African Americans and Asians. (National Library of Medicine 2010, para 2) This condition can be difficult to diagnose, as a patient must present a number of the recognizable symptoms. Depending on the location that Lupus presents itself in the body, the symptoms

Systemic Lupus Erythematous will affect people in different ways. The joints, lungs, kidneys, blood, the heart affected are the worst affect Systemic, .Lupus Erythematous can damage a person that have it. The type of lupus is also often categorized by periods of flare when the disease is living and periods of decrease when the disease is hidden. The signs and symptoms range from rashes on the cheeks, Ulcers in your mouth, red palms and hands, joint pain, joint redness, swelling of the joints, their face and legs become very swollen, the shortness of breath, rapid or irregular heartbeat, chest pain, hair loss, swelling of lymph glands, protein in the urine, increase sensitivity to the sun and last but not least mental changes. The people that have lupus in the blood will be affect because they may start developing anemia, leukopenia which is a decreasing number of white blood cells, or thrombocytopenia which is a decreasing in the number of platelets in the blood, which assist in clotting. A lot of people with the disease lupus that on autoantibody called antiphospholipid antibodies have an increased risk of blood clots. The people that have lupus in the heart are at risk because of the inflammation can occur in the heart itself or the membrane that surrounds itself (pericarditis), causing chest pain or other symptoms. The disease lupus have endocarditis which can damage the heart

The attacking and confused immune system has an assortment of organ systems to choose from and hate on, some common victims are the kidneys, skin, heart, central nervous system, the opportunities are many. Therefore, the symptoms of Lupus vary accordingly. If your stupid Lupus attacks your kidneys, you have kidney problems. If it 's your skin in the crosshairs, you have terrible rashes. If it 's your brain, you have headaches that make you want to poke your eyes out. It 's a real picnic.

They found albumin in the urine of some of the patients and described in detail of an eighteen year old girl with a malar rash, peripheral edema and hematuria. She rapidly developed diffuse skin disease, dyspnea, pleural effusion as well as urine sediment with albumin, white blood cells and casts along with red cells. She died and underwent an autopsy that showed glomerulotubular nephritis, an inflammation of the glomeruli which are bundles of tiny vessels inside the kidney. A twenty four year old female patient was said to have lupus erythematosus by the referring physician, Doctor George Fox. She had presented earlier with a malar rash, fever, lymphadenopathy and possible pleurisy versus infectious pneumonia. Eventually she developed femoral vein thrombosis, weight loss, and renal disease with red blood cell casts. Her white blood cell count at one point was 6000, but differential count was not reported. She most likely had Systemic lupus erythematosus (SLE). (R. Hal Scofield, MD and James C. Oates,

Makover, M. & Zieve, D. (2011, February 14). Systemic Lupus Erythematosus. National Center for Biotechnology Information. Retrieved July

Systemic Lupus Erythematosus is a chronic autoimmune disease which causes inflammation of your joints, tissues, and organs. The inflammation presents itself as heat, pain, swelling and redness. SLE is a variable disease that doesn’t take any one particular course; therefore its unpredictability makes it even more devastating. No two people will experience the same disease symptoms or severity level. As S.L.E progresses there will be periods of very subtle to no symptoms at all called remission or an exacerbation of symptoms called flares.

     Lupus is a potentially life threatening disease that effects about 1.5 million Americans. Lupus can effect many different parts of the body. Lupus is a type of autoimmune system disorder in which the body cannot distinguish the difference between foreign antibodies and its own organs. So basically what happens is that the body ends up attacking its own organs thinking they are foreign substances. (The Lupus Foundation of America)