The patient described pain in his back between the twelfth rib and lumbar vertebrae, which is the site to which the kidney is located; therefore it is possible that the patient suffered from a form of kidney disease. Upon urinalysis, it was found that the patient was suffering from haematuria. Haematuria typically results from an inability to filter urea, suggesting the patient was suffering from an infection to the kidney that inhibited its ability to filter urea which is symptomatic of swelling in the glomeruli. The patient was also suffering from proteinuria, Oliguria, and Oedema, reinforcing the possibility of an infection, arising due to the inability to filter urea. A throat culture revealed that the patient had suffered from …show more content…
The kidney is lined with millions of glomeruli which have projections called podocytes, which increase the kidneys surface area, and thus increase the absorption of nutrients from the blood. In a normal functioning kidney, filtration as a result is highly effective in removing macromolecules such as proteins. However the streptococcal bacterium causes the glomeruli to become inflamed, thereby inhibiting its ability to filter nutrients. Blood enters the kidney through the afferent artirol, which in a normal functioning kidney, has a smaller surface area comparatively to the efferent artirol; this increases the pressure of the blood, hence creating a pumping mechanism, through which substances move to the bowman capsule. However, when inflamed, the glomeruli expand, resulting in a decrease in pressurization causing blood to filter inefficiently. Resulting in substances such as blood and protein to enter the urine, as the glomeruli cannot filter large macromolecules such as proteins, resulting in hematuria and proteinuria.
STREPTOCOCCUS
Streptococcus is an infection caused by a bacterium known as streptococci. When fighting a bacterial infection, the body produces antibodies which identify the bacteria, such that it can be destroyed by the body. Typically, the streptococci are eliminated by way of urination, however it can become trapped within the glomerulus, and therefore cause
Consequently, the efferent arteriole, which filters blood away from the glomerulus, is tinier in diameter than the afferent arteriole, which carries blood into each glomerulus. This puts blood under high pressure in the glomerulus; thus it forces tiny molecules and liquid out of the capillary and into the Bowman’s capsule. Soon afterwards, the tiny and liquid molecules cross the epithelium of the Bowman’s capsule, the basement membrane and capillary wall in order to get into the Bowman’s capsule and to arrive in the nephron tubules. The consequence of this is that the filtrate (the tiny and liquid molecules) pass along the remainder of the nephron and helpful substances are reabsorbed along the route. Last of all, “the filtrate flows through the collecting duct and passes out of the kidney along the ureter” as mentioned by (Parson’s, R: p128).
The lower back pain could indicate a possible kidney infection, which is why I believe the doctor, told her to rush to the hospital.
This is an 82-year-old gentleman, who was referred from Dr. Gretchen Marsh’s office because the patient’s BUN and creatinine were high, as he has acute kidney injury. The patient went to Dr. Marsh’s office yesterday and was having generalized weakness. He does not have any vomiting. No diarrhea. No fever. No cough with expectoration. No sharpness. No wheezing. No headache. No dizziness. No passing out. No rectal bleeding. No hematemesis. No abdominal pain. No sore throat. No stuffy nose. No cough with expectoration. No burning, frequency, or
Both of our kidneys functions to filter and excrete waste products and toxins by regulating fluids, electrolytes, and acid based balance. If the Renal blood flow is altered then the glomerular filtration rate will be altered as well. A decrease in systemic pressure stimulates the sympathetic nervous system to constrict the renal artery and decreases filtration and secretion in the kidney. In addition, a tubular obstruction can lead to the reduction of Glomerular filtration rate. An elevated intracellular calcium level due to tubular damage may alter cellular level that increases tubuloglomerular feedback and diminishes GFR. This may be prerenal, intrarenal, or postrenal. The prerenal will result from any condition outside of the kidney that disables the blood to flow to the renal vasculature causing a decrease in perfusion in the glomerulus leading to oliguria. However, both of the kidneys can still return to its full normal function on this stage. Second of the three is intrarenal, where anything can cause a direct damage to both of the kidneys such as infections, toxins, reduce blood supply, hypertension, diabetes, and even glomerulonephritis. The most common intrarenal condition is Acute Tubular Necrosis, where the epithelial layer of the nephrons are damaged causing a change in the concentration of urine, waste filtration, and an imbalance in electrolytes and acid
I decided to look at the bacteria Streptococcus for my paper. I chose this particular bacteria because my daughter just got over having strep throat and I have been told that I may be a carrier of it. Strep throat is caused by the bacteria Streptococcal Pharyngitis (Group A). I will tell you in this paper what the signs and symptoms, ways it is diagnosed, and treatment options are for group A streptococcus more commonly known as Strep Throat.
“Streptococcus is a bacteria that infects the Immune System. The Immune System is made up of a network of cells, tissues, and organs that all work together to protect the body”("Immune Response"). According
Commonly referred to as strep bacteria.” (Streptococci and streptococcal Infections). Streptococci are normal bacterial residents on the skin and mucous surfaces outside or inside humans. Streptococcus contains a variety of species some of which cause disease in humans and other animals.
Synopsis: Acute Post-streptococcal Glomerulonephritis (APSGN) is the result of an antigen-antibody reaction where insoluble immune complexes develop and become trapped in glomerular tissue producing swelling and death of capillary cells. APSGN usually occurs after a latent period of one to three weeks following a sore throat or skin infection. It is occurs predominantly in children aged five to seven, and mainly affects boys than girls. The most likely cause of the throat infection in the six-year old child is due by a group A beta hemolytic streptococcal infection. The bacteria do not infect the kidney filters; it is the proteins from the blood that and proteins from the bacteria that injure the filers. He does not require treatment, as natural
Glomerulonephritis is a glomerular kidney disease in which the kidneys' filters become inflamed and scarred. There are different types of glomerulonephritis which include kidney disease of diabetes, IgA nephropathy, and lupus nephritis.Membranous nephropathy. GN is an immunologically mediated disease in which deposits of IgG and complement complexes collect in the basement membrane. The glomerular basement membrane becomes thickened and does not function normally, allowing large amounts of protein to be lost in the urine. In time, the kidneys slowly lose their ability to remove wastes and excess fluid from the blood to make urine.
1.Glomerulotubular Balance- this is a local renal mechanism. The proximal tubule is involved, and changes in oncotic pressure. Changes in hydrostatic pressure and delivery of certain solutes. When GFR increases protein concentration in efferent arteriole increases. Along with increase in oncotic pressure in peritubular capillaries. Increased gradient for reabsorption and balances increasing GFR on volume of fluid exiting proximal tubule.
Bacteria is found all over the world, from the depths of the ocean to the highest reaches of space. These microscopic organisms have not only created the world we live in, they have shaped our everyday lives more than we may know. Scientists continue to fight harmful bacteria on a daily basis, ever since Dr. Jenner developed and published the first successful vaccine, the search to cure disease has never stopped. As bacteria grows more unyielding to the current methods of deterring infection, we must continue to pursue new methods. One pathogenic bacteria that has been an issue to control is streptococcus. Streptococcus infections are among the many infections that still plague the public, and contemporary medicine is still at battle
Capsular hydrostatic pressure (CHP): hydrostatic pressure exerted by fluid within the capsular space of the glomerular capsule, and blood colloid osmotic pressure (BCOP): osmotic pressure resulting from plasma proteins, oppose the GBHP and create the net filtration pressure (NFP) of 10mmHg under normal conditions. This pressure promotes filtration of water and solutes (Jenkins, Kemnitz and Tortora, 2010). However with the drop of GBHP, the NFP will drop and even the small supply of blood that had not bypassed and entered the capillaries will not be filtered. Change in pressure and levels of solutes will affect other levels such as concentration gradients of solutes and osmotic pressure within the peritubular capillaries, interstitial fluid and renal tubules, which are vital during tubular reabsorption and secretion. As a result, nephron function will
This condition is caused by an increase in bacteria in the urine. This increase can be caused by:
Streptococcus affects the immune system, the body's disease-fighting (Hall 148). The immune system consists of the tonsils, thymus, lymph nodes, vessels, bone marrow, and the spleen (WebMD). Your body’s immunity is the ability to get rid of pathogens before they’re
Strep throat is an infection of the throat. It is caused by a germ. Strep throat spreads from person to person by coughing, sneezing, or close contact.