Christina Tran
Survival of the Sickest
Introduction
1.The “big” question that the book will attempt to answer is “Why would evolution- which is supple go weed out harmful traits and promote helpful ones- allow this gene (hemochromatosis) to persist?”
Chapter I
2.Iron extremely impactful in our life. One, it carries oxygen from our lungs through the blood stream and releases it in the body where it’s needed. Is also built into the enzymes that help us detoxify poisons and convert sugars and energy. Iron is also responsible for the healthy immune system function. Without enough iron in our system, skin gets pale, people can feel confused, dizzy, cold, and extremely fatigued. It explains why some areas of the world’s oceans are
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They evolved from viruses to attach onto human DNA.
B: Sunspots cause more radiation to hit the earth. If the radiation hits the viruses, the virus has a greater chance of mutating. This mutation is caused by antigenic drift which is when the mutation occurs in the DNA sequence of the virus. Antigenic shift is when the virus gets new genes from the newly mutated strands.
23.Genes have more than one job. They have multiple instructions to produce many proteins. If each gene had one purpose, there wouldn’t been enough to produce all the proteins needed for human life.
24.A persisting virus is a virus that is embedded in our DNA to help us evolve but also get passed down to offspring.
Chapter VII
25.A: A team of scientists at Duke University conducted an experiment on two groups of agouti mice. One group was fed vitamin supplements while the other was fed a regular diet. The agouti gene gives the mice a distinctive pale coat and tendency towards obesity. However, the mice that were fed vitamin supplements produced thin brown babies. This proves that certain genes can be turned off when conditions are
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Instead of losing telomeres after each reproduction, the cells replenish, or lengthen, the telomeres using an enzyme called telomerase.
D: The bigger a species is, the longer the life expectancy it has. Bigger animals are most likely to survive because their body is always reproducing new cells. One theory suggests that size matters in the food chain, such as smaller rodents clearly don’t have a longer life expectancy because they will most likely be food.
E: As humans evolved through time, we gained the ability to walk and stand upright, also known as bipedalism. This, however, made our pelvises smaller. Also, we humans started to develop the need for bigger brains. Big brains means big skull. Having a small pelvis makes giving birth much more risky because the fetus has a large head to fit through a small opening.
29.An iPod warranty is like the ability to replenish DNA in the body. Small animals have a short life expectancy because they don’t reproduce cells as fast as larger animals. If they’re cells reproduced as fast as a large animal, it wouldn’t make sense because they will be killed after a few years. Same goes for an iPod; if you were only going to keep it for a week, there’s no point in buying an extended warranty. It would just be a
d. In 3.a (above) you mutated one letter. What role do you think the redundancy of the genetic code plays in this type of change?
In chapter one it talks about how hemachromatosis is a hereditary disease and it’s the most common genetic disease for people of European descent, in which the body can't register that it has enough iron. So it keeps absorbing as much of it as possible, and this can have very, serious side effects (including death). Iron is very important for bacteria, cancer, and other things to grow. The way this disease is most easily treated is blood letting. Looks like all those crazy blood-letting, leech-sticking doctors weren't mistreating everyone. What is the author's argument for why this disease stuck around? To really simplify things: during the black plague in Europe, people with more iron in their system were more likely
Ever since life first appeared on the planet we call home, these organisms have been changing in a process called evolution. Evolution favors genetic traits that helps a species thrive and reproduce and tries to weed out the traits that threaten a species’ chance of survival. Genes that give a survival or reproductive advantage spread through the gene pool faster while genes that do not help a species get less common. This key mechanism of evolution is called natural selection. But even with evolution and natural selection, genetic diseases that make people sick are still in the gene pool after hundreds of thousands of years. So why would this happen? In Dr. Sharon Moalem’s Survival of the Sickest, he proposes that many of today’s deadly genetic
Essentially, iron is what allows almost every form of life to metabolize and function. In fact, our bodies body has several mechanisms that prevent access to iron to pathogens and other infectious bacteria thrive on iron that may harm our bodies known as the acute phase response. The author describes this as he states “the bloodstream is flooded with illness-fighting proteins, and, at the same time, iron is locked away to prevent biological invaders from using it against us (7).” So us readers can take away the idea that iron is crucial for our bodies. So how could potentially accumulating too much iron affect our health? That 's when hemochromatosis comes along. Our bodies assumes that the person is lacking iron in their system so they continually absorb the iron in the intestine. Not only that, don’t forget that bacteria and diseases also rely on iron to grow and accumulate.This can cause cancer cells to grow and spread continuously without stopping if it consumes our iron.
The lecture started off with Dr. Kitchens-Kintz discussing the importance of genes and what their functions are in the human body. For example, the fact that they are what contains the blueprints for proteins in our bodies. These proteins are then used for multiple important functions such as making up enzymes, hormones, and other materials such as collagen, which is an essential building block in hair, skin, nails, and bones. However, sometimes parts of genes get distorted throughout our life either from exposure to things such as sunlight or due to copying errors. These errors can can do one of three things: absolutely nothing, benefit, or hinder the individual. Furthermore, with the advancements in technology,
1. Viruses have genetic material enclosed in a capsid. They are an intercellular parasite. They are also extremely small in size. Their infections can be prevented by vaccines. The virus’s head is the capsid holding the DNA meanwhile its body is called a tail sheath and the tail fibers are the legs coming out of it. The two strategies for viral reproduction are through the lysogenic and lytic cycle. The purpose of the lysogenic cycle is to “build up” the virus. The original virus injects its DNA into the host cell, as the cell undergoes mitosis, the DNA that was from the virus will be replicated as well as the hosts regular DNA. At first the bacteria is known
Iron is basic to survive and have a healthy life as is the component that transport oxygen to
This little package of mayhem consists of relatively few parts. A virus is simply a protein capsule called a capsid, sometimes surrounded by an envelope, containing a genome. The genome consists of nucleic acids arranged as DNA or less commonly, RNA. Dozens of variants of this fundamental arrangement exist with differences in the structure of the capsule and the arrangement of the genome. Small differences or changes in these components allow some viruses to continue to outmaneuver researchers, while millions of dollars are spent trying to understand and eliminate them.
Iron is an important part of the human diet. Iron is what allows hemoglobin to form and hemoglobin transports oxygen across the body though the circulatory system. Despite its importance iron deficiency is the most common nutritional deficiency around the world.
A virus is a small infectious agent that replicates only inside the living cells of other organisms. Viruses can infect all types of life forms. A virus spreads upon contact. A virus can lay dormant for years inside a host. A virus can kill. Modern science now uses viruses to deliver gene therapy. Every year pharmaceutical companies take the flu virus and alter it to become our vaccine. A virus changes with each new host. One that mankind has been afflicted There are differing claims as to what constitutes truth, what things are truth bearers capable of being true or false, how to define and identify truth, the roles that revealed and acquired knowledge play, and whether truth is subjective or objective, relative or absolute.
Collins, J. P., Brunner, J. L., Miera, V., Parris, M. J., Schock, D. M., & Storfer, S. (2003).
In chapter 2, the idea of evolution was discussed. The debate between genetics vs. the environment was also examined more in depth. When learning about evolution in this chapter, the topics of natural selection and adaptive behavior were taught. I agree with both of these concepts of evolution. I believe in the process of evolution; in that we evolve from other forms of life. Natural selection and adaptive behavior are very relevant matters in the development of humans. I do believe that organisms learn how to survive from their natural environments.
In the book A Planet of Viruses, Carl Zimmer talks about viruses and how they have evolved in our earth. Throughout the book, he explains how viruses developed to dominate the outcomes of our health by constantly producing and spreading new diseases across species. New diseases are formed by viruses through mutation and reassortment. Zimmer explains that “reassortment allows flu viruses to mix genes together, into new combinations” (Zimmer, 18). At first, Zimmer explains how the word “Virus” had a different meaning in the beginning and had changed to acquire the meaning it is now. He then talks in each chapter about various viruses such as, HIV, swine flu, small pox and many other. He discusses about their impact on our environment, and how they originated. Viruses spread by animals, air or even mosquitos. This book also shows how the viruses are becoming more and more resilient to antibiotics, which controls the environment, our fate and the aspects of health.
A virus by definition is “any member of a unique class of infectious agents . . . that consists of genetic material, which may be either DNA or RNA, and is surrounded by a protein coat and, in some viruses, by a membrane envelope” (“virus”). Such agents are unable to produce the necessary nutrients to survive because they do not possess the biochemical mechanisms or organelles to synthesize necessary elements. As a result, they feed off a living host cell by attaching to the cell’s docking proteins and injects its virus through the membrane. However, the cycle of a virus is more complex than it may seem.
In order to fully understand these articles, one must have background information regarding the topic. Not only do you need to have a basic understanding of disease and infection, you have to understand what a viruses is. The Campbell Biology in Focus textbook describes a virus as “an infectious particle consisting of little more than genes packaged in a protein coat” (Campbell). We must understand that a virus consists