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Stage Iv Adenocarcinoma Case Study

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REASON
CHIEF COMPLAINT: Stage IV adenocarcinoma of unknown primary favoring a pancreatobiliary origin.

HISTORY OF PRESENT ILLNESS
Mr. Sullivan is a very pleasant 31-year-old gentleman who presents with a stage IV adenocarcinoma of unknown primary favoring a pancreatobiliary origin. In 10/2017, he presented to outside hospital with constant abdominal and back pain for 2-3 months. A CT scan was done which showed a multifocal hypodense lesions throughout the liver with retroperitoneal adenopathy. On 10/2017, he underwent ultrasound-guided liver biopsy, which showed an adenocarcinoma. Immunohistochemical staining was positive for cytokeratin 7 and negative for cytokeratin 20 and negative for CD 20 and TTF 1. This favored a pancreatobiliary origin. CT of the head was negative for metastases. He subsequently underwent an endoscopic ultrasound which showed no pancreatic mass. An ERCP was performed, which showed a stricture of the common bile duct in the left hepatic duct and stent was placed. His CA 99 was greater than 9000. His CEA was 5.6. He subsequently underwent an upper and lower endoscopy which were unrevealing for primary lesions. …show more content…

REVIEW OF SYSTEMS
A 12-point review of systems was performed and the pertinents are noted in the HPI.

PHYSICAL EXAMINATION
He is afebrile. Vital signs are stable. Generally, this is a cachectic man sitting in a wheelchair. No acute distress. Skin is warm and dry. Head is normocephalic, atraumatic. Pupils are equal, round, reactive to light and accommodation. Sclerae is anicteric. Oral mucosa is moist without lesions. No JVD. No thyromegaly. Lymphatics: No cervical, supraclavicular, axillary, or inguinal adenopathy appreciated. Respiratory: Lungs are clear to auscultation bilaterally. Heart: Regular rate and rhythm. Abdomen: Soft, nontender. Positive bowel sounds. Liver and spleen not palpable. Strength is 5/5 throughout. Neurological exam is intact.

LABORATORY

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