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Smoked Marijuana Summary

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Dr. Donald Abrams, who was originally denied the right to study medical marijuana by the DEA and NIDA in 1995, conducted a study to determine if using vaporization, a smokeless delivery system, could provide the equal results as smoked cannabis as well as reducing the risks associated with combustion byproducts produced by smoking. Abrams et al., (2007) utilized the Volcano device to determine the efficacy of a smokeless system. Cannabinoids were measured pre and post vaporization to determine if THC levels were comparable to levels received with smoked cannabis. It was found that using the smokeless system produced higher levels of THC concentrations in plasma at both 30 and 60 minute intervals as compared to smoked cannabis.
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Results showed that all doses of smoked marijuana and lower doses of Marinol were well tolerated and created an increase in calories eaten among low muscle mass participants with no significant effects on participants with normal muscle mass. All participants reported an increase in the production of feeling ‘high’ and having a ‘good drug effect’. No negative reports of mood were made however; the 30 mg dose of Marinol did cause over 20% of participants to experience headache, nausea, and feeling ‘overly …show more content…

Conclusion Marijuana is a drug that has been used effectively throughout history for medicinal purposes. Due to the effect it exhibits on the endocannabinoid system, it has been shown to provide relief of (a) chronic pain, (b) neuropathic pain and spasticity related to MS, (c) nausea and vomiting, and (d) anorexia related to AIDS wasting. Other research completed by the CMCR and being submitted for publication deals with neuropathic pain related to spinal cord injuries and diabetes (Grant et al., 2010 & Grant et al., 2012). However, much more research is
MEDICAL MARIJUANA 14 needed to unlock the mysteries of the endocannabinoid system and what effects marijuana is capable of creating. More research is also needed to help physicians, legislators, and society as a whole become more (a) educated, (b) understanding of medicinal marijuana, (c) cognizant of how beneficial it can be, and (d) how safely it can be

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