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Sequencing Of The Neanderthal ( Homo Neanderthalensis ) Genome

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In the past few years, advancements in biotechnology and a growing collection of hominid bone remnants have allowed paleoanthropologists to gain insight into how populations of different archaic hominid species interacted. In particular, sequencing of the Neanderthal (Homo neanderthalensis) genome has provided evidence that the evolution of anatomically modern humans (Homo sapiens) was influenced by interbreeding and gene flow between the two species of Homo. By comparing Neanderthal and modern human DNA, researchers have been able to produce evidence that would support the notion that not only was interbreeding possible, but also that it likely happened and produced a selective advantage. Of the three theories that exist to explain the …show more content…

sapiens, such as Neanderthals, via interbreeding until they replaced these archaic hominids (Bonvillain and Miller 2013:272). Once it has been established that humans originated in Africa, we must then explore the possibility and likelihood of interbreeding taking place once they left.
Modern humans and Neanderthals could have experienced both post- and prezygotic reproductive isolation that prevented them from interbreeding (Garrigan and Kingan 2007:895). By examining extant primates, it can be observed that successful hybridization is possible if the two species are less than five million years divergent (Garrigan and Kingan 2007:896). Using this as a model, in the case of H. sapiens and H. neanderthalensis, it can be inferred that any postzygotic isolation would not have had enough time to evolve in the period since their divergence, about 370–600 thousand years ago (Garrigan and Kingan 2007:895). For this reason, prezygotic barriers would have been a more significant factor in determining the extent of interbreeding between archaic and modern H. sapiens (Garrigan and Kingan 2007:897). Unfortunately, it is impossible to directly observe mating behaviours that existed because H. neanderthalensis are extinct, but by looking at the raw genome, some inferences can be made. By sampling modern humans from different parts of the world, it was observed that Europeans and Asians both contained about the same small percentage of DNA (about 1 to 4 percent) that could be

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