Twenty Roliflo-OD® capsules were opened and emptied and the contents were accurately weighed. A portion of the capsules contents equivalent to 2.5 mg TAM and 25 mg TOL was weighed and accurately transferred into a 25-mL volumetric flask using about 15 mL methanol. On the other hand, twenty Vesomni® tablets were weighed and finely powdered. A portion of the tablet powder equivalent to about 2.5 mg TAM and 37.5 mg SOL was transferred into another 25-mL volumetric flask using about 15 mL methanol. The sample solutions of both flasks were sonicated for 15 min. In both flasks, the volume was completed to 25 mL using methanol and filtered through Whatman No. 1 filter paper. Portions of 1, 2 and 3 mL of each of the prepared Roliflo-OD® capsules sample
To begin the separation of the sucrose from the Panacetin, approximately 3 grams of Panacetin was transferred to a 125-mL Erlenmeyer flask. Added to the flask was 50 mL of dichloromethane to dissolve the Panacetin to aid in the separation. A fluted filter paper was used to filter the Panacetin and dichloromethane mixture by gravity using a glass funnel. The remaining filtrate was set aside than transferred to a separatory funnel and the substance on the filter paper was dried and weighed. The filtrate was extracted with 2 increments of 25-mL portions of aqueous 1 M sodium hydroxide. During this step the filtrate in the separatory funnel was shook and vented 3 times.
In experiment two, the drug Panacetin was separated by a series of chemical reactions into its three components: sucrose, aspirin, and an unknown active ingredient, either acetanilide or phenacetin. The purpose of this lab was to determine what percentages of each component is present in the pain-killer. The initial step was to dissolve Panacetin in dichloromethane. However, sucrose is insoluble in dichloromethane because organic molecules are soluble in organic solvents, and dichloromethane is an inorganic solvent, so only aspirin and the unknown dissolved. By using gravity filtration, sucrose was filtered from the solution and 0.30g of solid was collected.
From the vial labeled “AE,” aspirin (0.533 g) was placed into a 50 mL Erlenmeyer flask with a boiling stick. Toluene (20 mL) was brought to a boil on a hot plate. The boiling toluene (10 mL) was then added to the aspirin until the solid dissolved completely. After allowing the solution to reach room temperature, the solution was placed in an ice bath for 16 minutes. After the crystals
Rubisco is the most abundant protein on earth that is essential for carbon fixation in plants. For the protein to function at its optimal level, it needs to be isolated from the mixture of proteins and in its purest form. The three isolation techniques carried out in this lab are salting out, ion exchange chromatography, and SDS-PAGE. Rubisco will be purer as each technique is conducted and will be in its purest form after the last isolation technique is carried out.
During Phase 1, sufficient information about the drug’s pharmacokinetics and pharmacological effects should be obtained to permit the design of well-controlled, scientifically valid, Phase 2 studies.
Introduction Proteins are critical components in understanding cells and organisms which can contribute to further developments in medicine. Proteins compose more than 50% of the dry weight of cells [2]. Enzymes are the proteins that catalyze most reactions in a cell that keeps the cell going. By isolating protein scientists can understand, modify, and sequence specific proteins away from other cellular components. The specific protein being looked at is Rubisco (Ribulose-1,5-bisphosphate carboxylase/ oxygenase) which is a plant enzyme that has a key role in photosynthesis [1].
Intermediate stability tests will be performed on samples from these batches of capsules at 30°C ± 2°C/65% RH ± 5% RH over a period of 6 months. Accelerated stability tests will be performed on samples from these batches of capsules at 40°C ± 2°C/75% RH ± 5% RH over a period of 6 months. These will also be tested according to the following matrix design.
The National Prescribing Centre recognize some fundamental differences in the absorption, distribution and excretion of medicines between adults and children. The differences are published in the National Prescribing Centre’s bulletin, produced by
The filter paper, holding the aspirin crystals, was removed from the funnel and was left to dry before being weighed. Once the aspirin crystals were weighed, the theoretical yield and the percent yield of the experiment were calculated. The procedure was repeated once more using the same steps.
Vimax capsule is a penis expansion pill that claims that you can expand your penis size to as much as 3 inches while you to take it. Is there any reality on this? Do Vimax capsules work? It's made using average ingredients from plants.
Americans spend $ 1.2 billion annually on the country’s third most popular dietary supplement; is it worth it? Recent studies have shown that Fish oil capsules can potentially cure Schizophrenia, a mental disorder in which people interpret reality abnormally. Seven years ago, a clinical trial using Fish Oil capsules as treatment was conducted and led to the discovery of Omega-3 fatty acid reduces the likelihood of youth developing psychosis.
In this experiment, the techniques utilized for the determination of the unknown concentration of riboflavin was standard addition and obtaining
Of the three components likely to be present in your sample of Panacetin (aspirin, acetanilide, and starch), only starch is insoluble in the organic solvent dichloromethane (or methylene chloride), CH2 Cl2. If a sample of Panacetin is dissolved as completely as possible in dichloromethane, the insoluble starch can be filtered out, leaving acetanilide and aspirin in solution. The purpose of this experiment is to extract the components of Panacetin.
In this essay, I will try to develop three factors that about a drug named Meloxicam, although in the essay it will be referred to as Mofix. The three factors are: 1) Use of the drug in pregnancy and breastfeeding. 2) Indications and dosage instructions. 3) Formulations available for the drug and routes of administration. In spite of the details of each factor, there will be a conclusion at the end signifying one important fact from each of the three, in order to try and simplify the facts that are written.
Unlike modern medicine, herbal drugs can be adjusted according to the condition of each patient. The diagnostic approach depends on the tailored requirements according to the