preview

Ritalin Abuse

Decent Essays

The Food and Drug Administration (FDA) first licensed methylphenidate hydrochloride in 1955 for treating what was formerly known as hyperactivity, attention-deficit disorder or ADD. The drug was commonly prescribed in the 1990s when the diagnosis of ADHD became better known and accepted. In 2000, Janssen Pharmaceuticals received approval from the FDA to market Concerta, an extended-release form of Ritalin. Approximately two-thirds of 6.4 million children presently diagnosed have been prescribed drugs like Ritalin or Adderall (another common CNS stimulant).

First synthesized in 1944, the Ritalin formula (at that time commonly known as MPH, from methylphenidate) was improved in 1950, and by 1954 it was being tested on humans. In 1957, Ciba Pharmaceutical Company began marketing MPH as Ritalin to treat chronic fatigue, depression, psychosis associated with depression, narcolepsy, and to offset the sedating effects of other medications. It was used into the 1960s to try to counteract the symptoms of barbiturate overdose. Ritalin has a high potential for abuse when injected it may produce feelings of euphoria. Those who misuse Ritalin increase the amphetamine-like effects by crushing the tablets into a powder and snorting it or dissolving it in water for intravenous injection. …show more content…

While amphetamines stimulate the release of dopamine, cocaine and Ritalin block the transporters that reuptake dopamine into the neuron that released it. By blocking transporters, Ritalin allows more dopamine to reach receptors, thus increasing attention signaling, which helps people with ADHD to focus. Ritalin, when taken orally, slowly raises dopamine levels over the course of an hour or so. By contrast, when inhaled or injected, cocaine reaches the brain in seconds, producing a

Get Access