Rheumatoid Arthritis Response Paper

Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And

Rheumatoid arthritis is a disease that has direct involvement with the immune system. This disease is considered to be degenerative and currently the only thing that can be done is manage the painful symptoms and suppress the self targeting actions by using immune suppressing drugs. The cause of rheumatoid arthritis is mostly unknown but there is a high amount of evidence that there are genetic predispositions for the disease. This being said however there are also environmental factors to asses these include, bacteria, viruses, fungi and other environmental factors. Doctors primarily use a physical examination to first suspect R.A. then send for blood work to confirm. There are many aspects to this disease and many questions left

Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small hand joints. RA is

Rheumatoid arthritis(RA) is a typical, chronic autoimmune disease that primarily affects the joints, ultimately leading to synovitis that often develops into cartilage and bone erosion, apart from which, extra-articular features are presented, including sub-cutaneous nodules, vasculitis and pulmonary fibrosis, particularly in severer cases. Animal models of RA have proven to be useful tools for pre-clinical reasearch as well as for the study of pathogenesis due to the fact that animal

Rheumatoid arthritis (RA) is a chronic, complex and systemic inflammatory disorder that affects up to 1% of the population (1-2). It’s an autoimmune disease of unknown etiology. RA is associated with progressive joint destruction, systemic complications and early morbidity. The disease is characteristic of inflammation of the synovium, autoantibody production, cartilage and bone destruction and other systemic consequences, many of which include cardiovascular events. Although structural changes can be visualized by conventional imaging techniques, joint damage is rarely apparent in early stages of disease, but rather accumulates over time (3). Various immune modulators and signalling pathways are involved in the pathophysiology of RA. The influx

RA is a chronic, systemic and inflammatory disease that progressively impacts peripheral joints (Panayi 2011).The damage that occurs is predominantly symmetrical and polyarthropathic (Rindfleisch & Muller 2005). It affects the host’s joint synovial membranes, tendon sheaths and bursae and causes stiffness, pain and swelling to the joints

Rheumatoid arthritis is an autoimmune and systemic disease damaging many joints in all parts of the body. In this state, body’s immune system activates a self-regulated immunological cascade that ultimately leads to joint damage. Rheumatoid arthritis begins in synovial tissues attached to the joints and then extends towards cartilage. It is described by

So far, researchers have found genetic and environmental factors to play the largest role in the causes of Rheumatoid Arthritis. (“Early treatment of rheumatoid arthritis is important,” 2016). Researchers have found that the genetic makeup of a person can help pre-determine if a person will be diagnosed with Rheumatoid Arthritis, and even goes on to pre-determine how intense the disease will affect the individual. Although the environmental factors are still being researched, scientist are beginning to believe that there is an environmental trigger that happens to bring on the onset of Rheumatoid Arthritis in an individual. (Vital, Communications, & Liaison, 2016) It is found that hormones also play a role in the development of Rheumatoid Arthritis. Research followed this theory once Rheumatoid Arthritis began appearing more in women than in

As a result of joint pains caused by inflammation the ability to engage in physical activities becomes diminished and this affects human fitness. RA is associated with other comorbid diseases such as hypertension, asthma, chronic obstructive pulmonary disease (COPD), diabetes mellitus, tuberculosis and chronic liver disease amongst other diseases (6).

Although life bestows upon everyone various challenges, a patient suffering with rheumatoid arthritis has a grim and debilitating existence. Thus, Rheumatoid Arthritis (RA) is a form of arthritis that produces pain, inflammation, stiffness, redness, tenderness, and extreme deformity of many joints of the human body. Thus, everyday activities pose a significant obstacle for a patient with this enervating condition. Surprisingly, most people RA lead highly productive, full, and rather satisfying lives. Consequently, there are is an estimated two to three million Americans diagnosed with rheumatoid arthritis, and about 200,000 newly diagnosed cases annually. Therefore, about 1 percent of the population has this condition, which affects people of all races and nationalities in this country. Even though, citizens at all stages in life can develop rheumatoid arthritis, it is most commonly touches people in their twenties, thirties, and forties. Nevertheless, research reveals that RA is three times more prevalent in women populace than men (Shlotzhauer and Hoplans 2014). Therefore, this brief research will disclose the definition of Rheumatoid Arthritis, patient prevalence, diagnosis, prognosis, and what patients experience that suffers with this condition.

If you’ve recently been diagnosed with inflammatory arthritis, or think you might be feeling the onset, please contact us. We’re here to

Rheumatoid arthritis (RA) is an autoimmune disease (McInnes & Schett, 2011; Smolen & Steiner, 2003; O'Dell, 2004) wherein the immune response of the body is aberrant, tagging the healthy cells of the body as non-self or foreign which therefore leads the body to attack and eliminate its own tissues. RA affects the synovial joints and is characterized by joint inflammation and the tissues surrounding it (Curtis, Gaffo, & Saag, 2006). Moreover, around millions of the Earth’s population are diagnosed with rheumatoid arthritis (Bingham & Ruffing, 2016). Patients detected to have this disease experience pain, stiffness or swelling in their joints (Centers for Disease Control and Prevention, nd; Drane, Berry, Bieri, McFarlane, & Brooks, 1997; Bellamy,

Rheumatoid Arthritis (RA) is a chronic autoimmune disease of the joints that affects approximately 1.3% of the world population1. RA causes inflammation in the tissue lining the joints, which leads to joint swelling, pain and stiffness2. RA occurs three times more often in women compared to men3. While this sex bias in the prevalence of RA is not yet understood, it has opened a new field of research to investigate sex differences in RA and to gain a better understanding of the etiology and progression of this debilitating disease. Note: Although the terms sex and gender are used to refer to biological vs. psychosocial differences respectively, we have used these terms interchangeably in this paper to refer to sex/gender-related factors to

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Osteoarthritis is a low-grade inflammatory condition as opposed to rheumatoid arthritis which is a high-inflammatory disease. The progression of these two diseases can be represented by the presence of inflammatory cells; for example, certain cytokines (IL-12, IL-6, TNF-α) are increased in the synovial fluid of patients with osteoarthritis which is speculated to be