Rheumatoid Arthritis or “RA” is an autoimmune disorder where the immune system mistakenly attacks its own body tissues. This disease affects the lining of joints causing pain and swelling. Eventually the swelling can lead to bone erosion and joint deformity. RA can happen to anyone at any age, but the majority of people who have to endure this disease are women over the age of 40.
Pathophysiology
Rheumatoid Arthritis is a joint attacking disease, but RA can attack any organ in the body. There is no unique test to diagnose RA, doctors look at signs and symptoms of the patient. Infectious agents have long been suspected as potential triggers of RA. Some external triggers, such as smoking, infection, or trauma could even affect the
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RA can affect anyone, but women are the ones who usually suffer the most. The best thing to do if a person notices symptoms is to go to their doctor immediately, doing so could catch the symptoms before they get worse and do
Rheumatoid Arthritis(RA) is the most common type of autoimmune arthritis. RA is a progressive and debilitating musculoskeletal disorder that affects the joints symmetrically, causing a range of systemic effects. What it causes is still not well known; nevertheless, findings of new research points towards a believe that it is triggered by a defective immune system, which causes the release of inflammatory chemicals. These chemicals cause damage to cartilage and bone, usually affecting the wrists, the joints of the hand, including the knuckles, the middle joints of the fingers and feet. While this condition can affect any joints, besides, important body organs such as the eyes and the lungs can also be affected by the inflammation that occurs as a result of this chronic condition. Only in America 1.3 million of people are affected by this ailment, and 75 % of them are mainly women. Its onset usually occurs between fourth and sixth decades; however, RA can occur at any age("Diseases And
“Rheumatoid arthritis is a type of chronic arthritis that occurs in joints on both sides of the body, such as both hands, both wrists, or both knees. This symmetry helps distinguish rheumatoid arthritis from other types of arthritis”. If a joint is deemed as arthritic that means that there is inflammation within the joint. Inflammation within a joint can cause swelling, redness, warmth and pain within that joint. Rheumatoid arthritis primarily affects the joints, but may also affect the skin, eyes, lungs, heart, blood, or nerves. Rheumatoid arthritis can present itself in many different ways. For some, joint symptoms develop gradually over several years, while others may develop quickly. Some people are affected by rheumatoid arthritis for a short
Today in the United States there is an estimated 1.3 million people living and dealing with rheumatoid arthritis (Arthritis Foundation). One might ask, what exactly is rheumatoid arthritis? Well, rheumatoid arthritis, also commonly known as RA, is a form of inflammatory disease and an autoimmune disease. If the person is a minor, or below the age of six-teen, then the chronic disease can also go by the name of juvenile arthritis. The juvenile arthritis is, “Defined as chronic inflammation of the synovial joints, with unknown etiology, which starts before the age of sixteen and persists for at least six weeks” (Hink et al 1). This disease can affect anyone with a functioning immune system. Out of the 1.3 million people in the United States that have rheumatoid arthritis, 70% of that number is women (RA.com). Once again there are no certain reasons as to who receives this disease whether its children, elders, Caucasians, African Americans, etc. But once they do receive the illness, then it affects them immensely. “The disease is systemic, meaning it can occur throughout the whole body. It’s a chronic disease, so it can’t be cured” (Arthritis Foundation). The pain, stiffness and fatigue can affect the entire body. “RA occurs when your immune system, the system that protects your body from outside harm, mistakenly starts attacking healthy tissue” (RA.com). Rheumatoid arthritis is an incurable disease that is affecting
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small
If ones doctor suspects RA they may perform blood test to check for protein in the blood (This is present in about 2 in 3 people with RA. However, about 1 in 20 of the normal population has rheumatoid factor), and x-rays of the hands and feet may be done to detect any early deformations of the joints. If an individual’s doctor suspects that they may have RA, they usually will refer the patient to a rheumatologist who specialize in the joints and this type of disease. There is no cure for RA, but proper treatment for RA can make a big difference in reducing symptoms and to improve quality of life. Some of the main aims of treatment are: to decrease the disease from progressing to prevent joint damage, to reduce pain and stiffness in the affected joints, to minimize any disability caused by pain, joint damage, or deformities. A common medication prescribed for RA are disease modifying anti-rheumatic drugs (DMARDS) such as methotrexate, sulfasalazine, and hydroxychloroquine. This can be with medication such as steroids, NSAIDS, and often times will treat with pain killers because the pain is so intense. Eating a healthy diet and excising is always
Rheumatoid arthritis is a chronic, systemic autoimmune disease characterized by inflammation of connective tissue in the diarthrodial (synovial) joints, typically with periods of remission and exacerbation (Lewis, Dirksen, Heitkemper, Bucher, & Camera, 2011). The etiology of rheumatoid arthritis is unknown. Autoimmunity and genetic factors are believed to be important in the development of RA. Genetic predisposition appears to be important in the development of RA (Lewis et al., 2011). The strongest evidence for a familial influence is the increased occurrence of a human leukocyte antigen (HLA) (Lewis et al., 2011). Smoking can increase the risk of RA for a person who has a genetic predisposition. Autoimmunity theory suggests that changes
Rheumatoid Arthritis or (RA) is an autoimmune disease that attacks the joints and connective tissue. The result is inflammation that produces permanent damage in the joints. Rheumatoid arthritis is a chronic syndrome that tends to be progressive and destructive as compared to Osteoarthritis or (OA), which is more of an age related disease caused by “wear and tear” of the joints. In contrast to (OA), rheumatoid arthritis is characterized by inflammation mostly of the joints, but is a general body disease.
Rheumatoid Arthritis is a systemic autoimmune disorder. There are more than 100 different types of Arthritis, yet it is estimated that it affects approximately 1% of the population in the Western World. The disease is generally diagnosed in middle aged adults and the elderly. In rarer cases, children can also develop the disease and it is called Juvenile Rheumatoid Arthritis. Women are three times more likely to have rheumatoid arthritis than men. (Stevens) Many people living with Rheumatoid Arthritis appear to be healthy individuals, but suffer internally. Today, I will discuss what rheumatoid arthritis is, how it is diagnosed, and how it affects the body.
Rheumatoid arthritis is a chronic syndrome that is characterized by inflammation of the peripheral joints, but it may also involve the lungs, heart, blood vessels, and eyes. The prevalence of this autoimmune disease is between 0.3% to 1.5% of the population in the United States (Feinberg, pp 815). It affects women two to three times more often than men, and the onset of RA is usually between 25 and 50 years of age, but it can occur at any age (Reed, pp 584). RA can be diagnosed by establishing the presence of persistent joint pain, swelling in a symmetric distribution, and prolonged morning stiffness. RA usually affects multiple joints, such as the hands, wrists, knees, elbows, feet, shoulders, hips, and small hand joints. RA is
Arthritis affects more than just the joints. Rheumatoid arthritis is an autoimmune disease where the immune system attacks various joints, internal organs,
Rheumatoid arthritis (RA) is an autoimmune disease that affects the cartilage in one 's joints, it is not curable, it can not be stopped, only the pain itself can be lessened. In an average person’s body, the immune system has one job; to attack foreign substances that may enter the body. With the 1.5 million people in the United States that have been diagnosed with rheumatoid arthritis, their bodies are “tricked” or mislead into thinking that the cartilage within their joints is what is foreign. Once their immune system attacks the joints, it causes inflammation within, which then in turn leads to the synovium (lining of the joints) tissue to thicken. The synovium makes a fluid that acts as a lubricant to the joints and helps everything move freely. Once that fluid is gone, swelling and pain is experienced next. After awhile, the cartilage within the joints begins to disintegrate and will eventually cripple the individual. Along with knowing exactly what RA is, by the end of this paper you will know signs and symptoms within the oral cavity and systemically, and you’ll be familiar with how nutrition is related to the progression of this disease.
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the
Patients primarily complain of pain, morning stiffness, and edema (swelling) of their peripheral upper limbs and lower limbs joints (Hochberg et al. 2009). The joints most commonly involved initially are the metacarpophalangeal (MCP) joints, proximal interphalangeal joints (PIP), wrist, and metatarsophalangeal joints (Taylor 2007; Harnden et al. 2016). Although RA is primarily affect the musculoskeletal system, the systemic inflammation properties may affect other body organs and systems (Extra-Articular), causing vasculitis, fever, weight loss, fatigue, pleuritic, pericarditis, endocarditis, neuropathies, scleritis, and episcleritis (Cojocaru et al. 2010).
In the article is discusses rheumatoid arthritis (RA) and its characteristics. It states that during RA synovial joints, like pivot, hinge, saddle, plane, condyloid, and ball-and-socket, become inflamed causing the joints to become hot, swollen, stiff and painful. It also states that RA is most likely going to start in the small joints of your hands and feet. RA is a very serious disease that if left untreated can lead to permanent joint damage that has no cure; however, there are some treatments to the disease that if started early enough can prevent damage.
Results Th is study included 60 RA patients (55 female and fi ve male). Th ey were diagnosed according to the2010 American College of Rheumatology/European League Against Rheumatism classifi cation criteria for RA (ACR/EULAR), recruited from patients attending the outpatient clinics of Physical Medicine, Rheumatology and Rehabilitation Department of Menoufi a University Hospitals. Th e patient characteristics are presented in Table 1. In all, 20 apparently healthy volunteers matched for age and sex with the patients were enrolled in this study.