Repeating DNA Fingerprinting

Each human being has something called DNA. DNA is described as genetics and an extremely long macromolecule that is the main component of chromosomes and is the material that transfers genetic characteristics in all life forms. DNA constructs of two nucleotide strands coiled around each other in a ladder like arrangement with the sidepieces composed of alternating phosphate and deoxyribose units and the rungs composed of the purine and pyrimidine bases adenine, guanine, cytosine, and thymine. Each chromosome consist of one continuous thread-like molecule of DNA coiled tightly around proteins and contains a portion of the 6,400,000,000 basepairs that make up your DNA.

DNA samples can be extracted from hair, blood and skin. Siblings have different DNA fingerprints because everyone has 23 pairs of chromosomes and for each pair one is one of your mother’s chromosomes and the other is your father’s chromosomes. Other than identical twins no other people have exactly the same DNA. DNA fingerprinting is used every day to determine whose parents or siblings are whose, it is used in crime scenes to determine who was at the scene, can be used to determine where a certain inherited gene is inherited from and it can be used to identify a body that is deceased. During electrophoresis an electric current passes through the agarose gel, therefore moving the DNA samples through the gel. The smaller the DNA fragment the faster it moves through the gel. The finished product will look like a series of bands, some will match up and some won’t. The different bands in electrophoresis represent different gene fragments.

Identification means the steps needed in the analysis of unknown fluids to see what the substance is (“Biology,” 2016). Individualization determines whether a certain individual may or may not be the donor of a bodily substance by examining various markers (“Biology,” 2016). Processing biological trace evidence uses highly complex, automated technology to create a DNA profile that helps the investigators through the association of suspects to victims and to crime scenes (“Biology Services,” 2017). By using techniques such as polymerase chain reaction (PCR), forensic biologists can use variable markers found on the regular chromosomes (STR’s), the sex chromosomes (Y-STR’s) and within the mitochondrial DNA to distinguish one person’s DNA from another to a high degree of certainty (“Biology,” 2016). Forensic biologists are involved in assisting investigative agencies because police were led to Bernardo by a police sketch (“Serial Killers: Paul Bernardo and Karla Homolka,” 2013). The police took DNA (hair, blood and saliva) from Bernardo as a matter of routine to test it against specimens found on a rape victim’s clothing (Butts, n.d.). Forensic biologists were able to name the substances left on Kristen French’s body and match it to Bernardo’s DNA by processing it. On February 17th, 1995, Bernardo was arrested for the murders of Mahaffy, French, and the Scarborough rapes (Butts,

DNA is the genetic material that makes up the characteristics of all living organisms. While all human DNA is very similar in nature, there is just enough differences in

Indeed DNA profiling has rapidly transform the field of forensics. DNA profiling is the scientific analysis of evidence for crime scene investigation and other legal proceedings. DNA profiling is mostly used by forensic scientists and crime lab technicians. To identify criminals and victims using trace evidence like hair or skin samples. To produce a DNA profile, scientists compare sequences in the genome that vary from person to person. The typical steps in DNA profiling are DNA samples are isolated from the crime scene, suspect, victims, or other evidence. The next selected sequences from each DNA sample are amplified (copied many times) to produce a large sample of DNA fragments. Finally the amplified DNA regions are compared using a gel. All together, these steps provide data about which samples are from the same individual and which sample is unique.

The Australian Institute of Criminology has produced documentations explaining “the technique of ‘DNA identification’ compares the DNA of two bodily samples to ascertain whether or not they came from the same human being. Identity of DNA in the cells across both samples implies that the samples are derived from the same person (or identical twins); non-identity implies different human sources.”

DNA, Deoxyribonucleic Acid, is the basic structure for all life, it is the blueprint, the instruction manual, on how to build a living organism. DNA is made up of four nitrogen bases, adenine, thymine, cytosine, and guanine which are connected by sugar-phosphate bonds. Through a process called Protein Synthesis, the nitrogen bases are the code for the creation of amino acids. Essentially, DNA makes amino acids, amino acids make proteins, proteins make organisms. This process has been taking place for much longer than scientists have been able to document. Those scientists are called geneticists and their field is genetics.

Forensic DNA analysis is still a relatively new method that has been used to solve cases such as crimes and paternity tests. This method of forensic evaluation is examined by using genetic material, DNA, an acronym for deoxyribonucleic acid. Although each individual’s DNA differs from someone else’s, with the exception of identical twins, around 99.9% of DNA is the same in each person ("The FBI DNA Laboratory"). Therefore, in order to identify the genetic profile of the individual being analyzed, scientists focus on the remaining 0.1% of DNA that differentiates one person from another ("The FBI DNA Laboratory").

DNA analysis is a forensic tool that allows a suspect to be linked to a crime scene. Using the DNA analysis method, requires law enforcement officers to obtain DNA from the suspect and compare the suspects DNA,

Due to the uniqueness of DNA it has become a powerful tool in criminal investigations

DNA analysts have been profiling DNA since 1985. Then in 1998, the Combined DNA Index System became fully operational (“FAQs” 2010). CODIS’s three levels are the national level, the state level, and the local level. As September 2015, there is 14,740,249 DNA profiles in CODIS (“CODIS”, n.d.). Since everybody has different DNA, except identical twins, DNA analysts have been able to assists with investigator to determine between who is guilty and who is innocent. With some of their findings, they are able to exonerate individuals, who have been wrongfully convicted. Even though television may make DNA analysts’ life look simple on the screen, it is not. There is need for interest and education. Lastly, the actual job that entails for the DNA

When DNA replicates or its transcribed into RNA can cause changes in the sequence of bases which makes up the genetic code. Know that a set of three bases in a gene in DNA codes for a particular amino acid.

What is DNA? Is it these winding strands that look like ladders or is it what gives a person blonde hair and blue eyes? Actually, DNA is both of these things. DNA is a person’s genetic makeup–their hereditary blueprint passed on by their parents. It is a part of almost every cell in the human body. In each cell, a person’s DNA is the same; it stays the same throughout their lifetime. DNA is found in skin tissue, sweat, bone, the root and shaft of hair, earwax, mucus, urine, semen, and vaginal or rectal cells. The DNA found in a person’s saliva is the same as the DNA found in their blood. Parts of the DNA determine our physical characteristics, such as eye and hair color, height, and bone structure, but the

DNA fingerprinting is a scientific technology involving the extraction, replication and arrangement of strands of an organism’s DNA. This results in the formation of a genetically distinctive fingerprint that is unique to the organism which the DNA sample was originally extracted from. Because of the specificity of a DNA fingerprint, the application of this technology can have a substantial influence on many aspects of society. Accessibility to a DNA database allows for higher efficiency in forensic investigations, personal identification, maternal and paternal testing. The availability of a national database to police officers and forensic scientists would equate to increased productivity in investigations and prosecution of suspects in a

From cases such as OJ Simpson to Chandra Levy, DNA profiling also called DNA fingerprinting or DNA typing has played a major role in the criminal justice system. The law enforcement community uses DNA profiling to rule out or identify suspects. Unlike hair microscopy, bite mark comparisons, shoe print comparisons, and firearm tool mark analysis, DNA typing has been developed through massive scientific research and has undergone meticulous scientific evaluation (Innocence Project). DNA is a foolproof method of identifying a perpetrator of a crime.