Pulmonary Fibrosis

i. Cystic Fibrosis (CF) affects those that are homozygous recessive for the F508del mutation in the CFTR (Cystic Fibrosis transmembrane conductance regulator) gene

Cystic Fibrosis is a life threatening condition that causes severe damage to the lungs and digestive system. Developing this condition can change a person's entire life. Depending on the severity of the condition a person can be affected by mild symptoms such as shortness of breath, all the way to severe symptoms such as rectal prolapse, or even death. Screening is done on infants in all 50 states; therefore if a child has inherited Cystic Fibrosis it will be known in the first months of life. As professional staff members of a nursing community it will be necessary to help prepare the child and the family for the life of Cystic Fibrosis.

(mesothelioma.com). It is always fatal and forms in the protective tissues that cover the lungs, abdomen, chest cavity, gastrointestinal system, and the reproductive organs. It can cause pleural effusion, which is when excess fluids build up in the pleural space in the lungs. The pleural space is the area between the lungs and the chest wall, and the person coughs up the fluids. The more fluids are present, the more difficult it is for the person to breathe. Asbestosis is an illness caused by inhaling asbestos fibers that lodge deep in the lungs. Asbestosis causes scarring or triggers growth of excess tissue that is a condition called fibrosis. There is no cure for asbestosis, and it makes breathing extremely painful and often causes death from lung or heart failure. If those things do not happen the person will eventually suffocate.

What is Cystic Fibrosis? How does it affect people living with it? Cystic Fibrosis, also known as CF, is a life-threatening hereditary disease. It is inherited by a faulty cystic fibrosis transmembrane conductor (CFTR) gene from each parent (Kowalczyk, 2014, p. 74). This faulty gene makes a defective protein that does not work well and causes the body to produce sticky, thick mucus and very salty sweat("About CF: Causes, Signs & Symptoms of Cystic Fibrosis,"

What is Cystic Fibrosis? Cystic Fibrosis is a disease inherited past down from many generations. Another name for cystic fibrosis is called clubbing there are many other name terminologies for cystic fibrosis. The name of the disease originates from the tough tissue, which scars inside the pancreas, first documented in the 1930’s. The pancreas is one the major organ attacked by a faulty chromosome no.7 where cystic fibrosis has been found. A cystic fibrosis patient can have the recessive gene and both of his or her parents can carry the gene but not affected by the gene. The disease attacks the external glands, which includes (lungs, perspiration glands, gastrointestinal system, and a man’s masculinity). Cystic fibrosis can cause several different

Cystic Fibrosis (CF or CFTR) is a life threatening disease that causes the buildup of thick and sticky mucus in many organs and body systems, and the mutated genes are passed down from parent to child. It affects about 30,000 people in the US, about 5% of the U.S Population carries the disease, but they do not have it. CF is most commonly present in Caucasians and some Hispanic. CF is less common in African Americans and Asians. Although cystic fibrosis is rare in most race, if it is inherited, it can life threatening when it isn’t treated in the early stages.

There are many diseases that greatly affect our respiratory physiology; one of those diseases is cystic fibrosis. Cystic fibrosis, according to the National Institute of Health (2013), is an inherited disease of the secretory glands or exocrine glands. Not only does this disease affect our respiratory system, it takes a toll on our digestive system. The respiratory system includes the gas exchange from our external atmosphere and our internal environment. This gas exchange of oxygen and carbon dioxide through our atmosphere and lungs does play a roll with cystic fibrosis. Cystic fibrosis is inherited, it affects many parts of the body mainly the respiratory system, and there are many signs and symptoms to this overwhelming disease.

There are many incurable diseases in the world that affect an organism’s way of living. Cystic Fibrosis, a disease with no known cure, affects 1 out of 3600 Canadian child’s digestive system and lungs, while a person with sickle cell anemia is only expected to live forty to sixty years. Both of these diseases are similar in the way that they are inherited genetically; they are passed on from parents to their children. Scientists are producing a way to help these people called Genetic Engineering. This is a way of modifying an organism’s genome to produce a more desirable trait by manually adding new DNA.

Cystic fibrosis is a scary disease. The life expectance for people with cystic fibrosis is in batween thirties and forties. It was discovered in 1938. There are more than 1,500 mutations that have identified in the single gene.

Cystic Fibrosis is a recessive disorder that is a life threatening disease that causes persistent lung infections and progressively limits the ability to breath. Unfortunately, there is no cure for this genetic disorder, but Airway Clearance, Inhaled Medicines, and Pancreatic enzyme supplements can increase the person’s lifespan incredibly. There are about 70,000 people worldwide with this disease. Approximately 1,000 new cases of cystic fibrosis are diagnosed each year. The average human with cystic fibrosis lives to about 30 if they take their medicine.

Cystic fibrosis also known as CF is a rare life threatening genetic disorder. CF causes individuals with this disorder to have persistent lung infections, in turn limiting their breathing. Individuals with cystic fibrosis, have a mutated gene that causes a thick, build-up of mucus in the lungs. Generally, it affects many of the body’s organ systems and is only found in about 200,000 people per year in the United States. Cystic fibrosis is the most widely recognized, life-shortening hereditary sickness in Caucasians. It influences the vehicle of salt and water crosswise over cells and influences distinctive organs, yet lung infection is in charge of the dominant part of manifestations, weight of care, and lost years of life. The quality that causes the sickness has now been recognized and sequenced. (Junge et al., 2016)

Cystic Fibrosis or CF is a life threatening genetic disorder that mainly affects the lungs and digestive system. Cystic Fibrosis is most common among the Caucasian population, particularly people of northwestern European descent and is less common in people of African ancestry and is very rare in people of Asian ancestry. According to the Cystic Fibrosis Foundation, “an estimated 30,000 children and adults in the United States (70,000 worldwide) have CF” (Cystic Fibrosis Foundation, 2014).

Have you ever heard of cystic fibrosis? If so, do you know what it is? Well, cystic fibrosis is an acquired issue that causes extreme harm to the lungs and digestive framework. Cystic fibrosis influences the cells that deliver bodily fluid, sweat and digestive juices. These discharged liquids are regularly thin and elusive. Be that as it may, in individuals with cystic fibrosis, a damaged quality causes the discharges to end up thick and sticky. Rather than going about as a grease, the emissions attachment up tubes, channels and ways, particularly in the lungs and pancreas. Although, cystic fibrosis requires day by day consideration, individuals with the condition can go to class and work, and have a superior personal satisfaction than in

Can viruses used as vectors in the process of gene therapy be an effective treatment for Cystic Fibrosis? Firstly, Cystic Fibrosis is a genetic and recessive disease that mostly affects the lungs and pancreas. This leads to phlegm accumulation, salty sweat, male infertility, shortness of breath and increased risk of infection, which all contribute to premature death (CFF, 2017). Since it is recessive, you need two copies of the gene to manifest the disease, but 1/30 Americans have at least one copy of the gene, so it is easily passed on (Hulslander 2017). To treat this disease, some scientists believe a viral vector can be used in gene therapy while others say using a virus is too risky and suggest a non-viral approach, such as liposomes

Cystic Fibrosis is a genetic disease primarily affecting European descendants (Alvarez 1997). CF was noted in Germany since the 1700s by the saying, “A child whose forehead tastes like salt when kissed will soon die.” There are, on average 1,000 cases diagnosed every year and an estimated 30,000 people inside of the United States, and 70,000 around the world living with Cystic Fibrosis. Almost half is over eighteen years of age. Cystic Fibrosis triggers the body to produce thick, sticky mucus that impacts many organ systems negatively. CF care requires detailed daily care regimens. (Borowitz, Robinson, Rosenfeld, Davis, Sabadosa, Spear, 2009). CF also hinders the body’s ability to break down food by halting natural enzymes from the pancreas. If both parents carry the mutated gene, there is a one in four chance of conceiving a child with Cystic Fibrosis.