Prostate Cancer In Men

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The goal is to educate men about their risks and encourage them to get a screening. Age and race are factors with African American men having an increased risk factor and higher probability. The American Cancer Society estimates that 1 in 7 men will be diagnosed with the disease in their lifetime. Early intervention is key to a successful treatment plan.

Prostate cancer being a huge cause of mortality and medical expense in men age forty and above has only recently become a topic of general conversation to men in America (Plowden, 2009). African-American men are affected by prostate cancer at a disproportional level than all other men. They are diagnosed up to 65% more frequently and the mortality rate is twice that of Caucasian counterparts (Emerson, 2009). The African-American male is also less likely to take advantage of free prostate cancer screening (Oliver, 2007).

There are several different types of cancers in the world, including testicular cancer. Testicular cancer is a disease only found in males where uncontrolled growth of abnormal cells are found in the tesicles that is commonly seen in young men from the ages of 15 to 35. Although it is one of the most curable types of cancer, there are different types of testicular cancer where there are several cells that start in a different part of the tesitcles that can cause the development of one or more types of cancer. Testicals are the male sex glands which produce testosterone, hormones, and also make and store sperm. Tesicles, often reffered to as testes, are found behind the penis inside the scrotum, they are about the size of a golf ball, which usually make up one portion of the male reproductive system.

For example, age is the biggest factor. We all know that as men age and get older they run a higher chance of their prostate enlarging and developing cancer. Family history and race are also the other two big ones. If people in your immediate family have had the cancer, then you run a higher risk of contraction because you’re already genetically predisposed to getting prostate cancer. Also, African American men are more likely to be diagnosed with the cancer, with white and Hispanic men following behind. According to the CDC, from the years 1999-2013, black men had higher mortality and contraction rates than men of other races and ethnicities.1 Hormones are also a risk factor; should the male be producing a lot of testosterone could put him at risk.

Prostate cancer originates in the male prostate gland. Cancers in this gland are the most common malignancies, which grow very slowly, and can have minimal effect on a man’s quality of life. However, a tumor in the prostate gland can be problematic for men, especially black men, even though it is only about the size of a walnut. Located below the bladder and in front of the rectum, the prostate provides the fluid that nourishes and protects sperm cells in the semen. Researchers are still debating the cause of this disease, although certain risk factors such as age, ethnicity, culture, environment, diet, and family history, increase the chance of getting it. Prostate cancer affects African American men and early screening and detection are the key factors that can be used to prevent mortality and reduce morbidity, especially in the Brooklyn area.

Lay Abstract: Prostate cancer is a complex disease with multiple tumors originating independently at different stages of growth. Although morphological differences (morphological heterogeneity) has been well recognized, the underlying molecular complexity in each tumor foci has not been well studied. Tumor growth in each foci can be determined by independent driver molecular aberration(s). Understanding the molecular level of differences (molecular heterogeneity) in each tumor foci would help to differentiate the patients who may undergo indolent or aggressive disease course. Further, morphological differences mostly help to understand the stage of the disease, but it is not possible to select appropriate targeted therapy. If different tumor foci carry different driver molecular aberrations, targeted therapy for single molecular aberrations may not yield the curative benefit to the patients. Conventionally, systematic sampling of large tumor foci or high Gleason grade tumor foci have been considered for various genetic and molecular studies. In this approach smaller tumor foci with important driver molecular aberration and high metastatic potential can be easily missed. Therefore, using our novel approach, we propose to screen the entire prostate tissue (whole-mount prostatectomy specimen mounted on large glass slide) to assess molecular differences in each tumor foci using well characterized prostate cancer specific molecular markers.

By race, black men have the highest incidence rate of this disease with an incidence rate of 239.8 per 100,000 men, while Hispanic men have the lowest with a rate of 133.4 per 100,000 men. The death rate of African-Americans is more than double that of any other race with a mortality rate of 56 per 100,000 men2. Recent data indicates that cancer develops in 30% of black men ages 50-59 and in 39% of black men 60-692. This is in contrast to 8% of black men developing it between the ages of 40 and 49. Similar data has been shown for men with a family history . The age-adjusted death rate from prostate cancer has fortunately decreased by 3.4% between 2001 and 2006 and the lifetime risk of developing prostate cancer is 15.9% for American men (i.e. 1 in every 6 men) 2.

A man’s age is what will put him at higher risk for prostate cancer. Men who are at higher risk are men between ages 40 and 50 years old. It is very rare for a man to be diagnosed with prostate cancer but as it is not common to be diagnosed with prostate cancer it is more likely to be diagnosed with it after the age of 50. Let it be known that more than 220,000 men will be diagnosed this year with prostate cancer, and over 20,000 men will lose their life from it. These statistics have been increasing over the years because there is no answer in what causes prostate cancer.

Cancer of the prostate, a common form of cancer, is a disease in which cancer (malignant) cells are found in the prostate. The prostate is on the male sex glands, and is located just below the bladder and in front of the rectum. The size of the prostate is about the size of a walnut. It surrounds the part of the urethra, the tube that carries urine from the bladder to the outside of the body. The prostate makes fluid that becomes part of the semen, which contains sperm. Prostate cancer is most commonly found in older men.

Much isn’t said about the prostate and prostate cancer in the mainstream media, except that it affects mainly men who are 40 and older. The National Cancer Institute says it’s the second most common cancer in men in the U.S., after skin cancer. It is the second leading cause of death from cancer in men.

Prostate cancer is a cancer relating to the prostate, a gland located in front of the rectum and below the urinary bladder (ACS 2015). Prostate cancer only affects the male population because the prostate gland is only found in the male reproductive system (FIS 2015). Among the males in the world, certain males are at higher risk than others due to certain risk factors. One of the biggest risk factors is age (PCF 2015). Only 1 in 10000 men under the age of 40 will be diagnosed with prostate cancer however 1 in 38 men between the ages of 40 – 59 will be diagnosed (PCF 2015). This then shoots up further to 1 in 14 men among the age of 60-69 (PCF 2015). Over 65% of all prostate cancer diagnoses are in men that are over the age of 65 (PCF 2015).

In order to be treated for prostate cancer, there are several factors doctors must first look into. One of the most important factors is “what are the benefits/side effects of the treatment”? Sometimes no immediate treatment is necessary, mainly in men who were diagnosed in early stages. Some men may never need treatment at all, some just require surveillance of the prostate over time. Active surveillance requires the male to have regular appointments, blood test and rectal exams to keep watch on the prostate and the progression of the cancerous cells. The first form of treatment is radiation therapy. Radiation therapy is the use of high-powered energy to kill cancerous cells. This form of therapy can be administered in two

A heart-warming house dog to a wild creature that led the pack of wolves in the wild. This is the story of Buck, a mix of Saint Bernard and Scotch Shepherd, leaving his past with the humans to join his kind and fight with them. It was a continuous journey of horrifying events and everlasting endurance. Buck suffered more than he ever had or ever would, it was preparing him for what lay ahead. Was it the smartest decision to leave or should have Buck returned to where he came from? It was all Buck’s decision and there were plenty of signs pointing towards the return to the wild. All connections were lost from humans and civilization, at the end there were no more bonds holding him back. He was free and was able to reconnect with what