Phototherapy also known as light therapy involves the use of light to treat different diseases and disorders. The light can come from exposure to the sun or from lasers, light-emitting diodes (LEDs), fluorescent lights, and more. It has the ability to treat a wide range of diseases from skin conditions to eye problems to mood and sleep related disorders. Skin conditions that can be treated with light therapy include atopic dermatitis, vitiligo, and psoriasis while retinal conditions like diabetic retinopathy and diabetic macular edema can also be treated with phototherapy. Current treatments of seasonal affective disorders or sleep disorders continue to be researched and studied, but one of the best and most effective uses of light therapy …show more content…
Cremer in the Lancet. Dr. Cremer was the first pediatrician/general practitioner who first introduced people to using phototherapy to treat neonatal jaundice when he observed the falling values of bilirubin when the blood serum samples were exposed to light. Clinical trials in the 1960s confirmed Dr. Cremer’s findings and led to phototherapy being regularly prescribed for neonatal jaundice, saving millions of lives. It also proved to be extremely effective for low birth weight infants with jaundice, seeing the greatest rates of improvements.
B. Description
Neonatal jaundice is a disease which has been known since ancient times (figure _). It is visibly seen when bilirubin levels surpass 5 mg/dl (85 mmol/l) in the blood. Bilirubin is a waste product of fetal blood transitioning to adult blood and causes brain damage or even death when left untreated. It accumulates due to the inability of the undeveloped liver to process the waste product. According to the worldwide statistics, jaundice is detected in 60% of full-term babies and 80% of preterm babies. That’s between 60–70 million babies worldwide (1).
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Symptoms of neonatal jaundice include excessive sleepiness, diet interference, and even brain damage in extreme cases. If the bilirubin blood concentration is too high, irreversible brain damage, and even death, can occur without treatment. Phototherapy causes this harmful bilirubin to absorb photons from light at around 450 nm and induces photochemical reactions, causing the formation of three major products that helps increase the elimination of bilirubin. Since bilirubin is often found to be bound to albumin, globular proteins that regulate the osmotic pressure of blood, the maximum absorption spectrum is actually shifted to the right into a range of about 450-475 nm. Visible light, specifically blue light falls within this range, which is why blue visible light is most effective in treatment neonatal jaundice. The photochemical reactions involve light shining on bilirubin, causing it to absorb photons and create bilirubin in an excited state. This photo-oxidation was widely thought to be the mechanism for bilirubin passage and excretion. However, in 1984, it was found that in fact isomer formation was the mechanism behind this excretion. Bilirubin undergoes from an insoluble cis- to soluble trans- conformation that allows the waste product to be eliminated through bile and urine. This is known as a figuration isomerization as known in figure
Premature babies sometimes have apnea. It may happen together with a slow heart rate. Respiratory distress syndrome or RDS is a breathing problem most common in babies born before 34 weeks of pregnancy.” Babies with RDS don’t have a protein called surfactant that keeps small air sacs in the lungs from collapsing. “Intraventricular hemorrhage or IVH is bleeding in the brain. It usually happens near the ventricles in the center of the brain. A ventricles is a space in the brain that’s filled with fluid. Patent ductus ateriosus or PDA is a heart problem that happens in the connection between two major blood vessels near the heart. If the ductus do not close properly after birth, a baby can have breathing problems or heart failure. Heart failure is when enough blood can’t get pumped into the heart causing it to shut down. Necrotizing enter colitis (NEC) is a problem with a baby’s intestines. It causes feeding problems, a swollen belly and diarrhea. It sometimes happens 2 to 3 weeks after a premature bay has been born. Retinopathy of prematurity (ROP) is an abnormal growth of blood vessels in the eye. ROP can lead to vision loss. Jaundice is when a baby's eyes and skin look yellow. A baby has jaundice when his liver isn't fully developed or isn't working well. Anemia is when a baby doesn’t have enough healthy red blood cells to carry oxygen to the rest of the body. Bronchopulmonary dysplasia (BPD) is a lung condition that can develop in premature babies as well as babies who have treatment with a breathing machine. Babies with BPD sometimes develop fluid in the lungs, scarring and lung damage. Premature babies often have trouble fighting off germs because their immune systems are not fully formed. Infections that may affect a premature baby include pneumonia, a lung infection; sepsis, a blood infection; and meningitis, an infection in the fluid around the brain and
Generally, bilirubin enters the liver and is transported to the liver where it is then secreted by liver cells into bile.
Some of the progressive signs of respiratory distress exhibited by this infant after birth are; nasal flaring, grunting, coarse breath sounds, increase respiratory rate of 100 and irregular, acrocyanosis, his appearance of being pale, circumoral cyanosis, and him developing jaundice as a result of his increased work of breathing and hypoxia which causes an increase in erythropoietin to be released from the kidneys resulting in polycythemia as a result of low levels of oxygen in the body. Subsequently, as a result of an increase or red blood cell production the body will develop jaundice due to an increase in red blood cell breakdown which causes an increase of bilirubin in the blood to accumulate, therefore, causing jaundice to develop.
that when the patient is exposed to the light there is a significant decrease in
found at tanning salons and some people even have their own personal ones in their homes. They contain about 24 to 60 lamps. There are two types of ultraviolet radiation that affect skin. They are called UVA and UVB. Tanning beds use more UVA light which penetrates deeper layers of the epidermis. People absorb more UV rays by using tanning beds rather than just tanning outside or at the beach. Some people just use them for special events like weddings or prom but the “radiation from just 10 indoor tanning sessions in two weeks can suppress a
The power of light is being used more in dermatology today, and just as blue light can help heal acne due to its bacteria-killing power, red light can repair sun damage due to its healing power. Light therapy is one of the least invasive ways to repair sun damaged skin, as it
Dermatologists, physicists, and scientists conducted a workshop of UVA treatment, and the workshop’s findings are presented in the New England Journal of Medicine. A previous president of the American Academy of Dermatology wrote an article titled “UVA1 is Often A1” to discuss their findings. The workshop found that medium or high-dose UVA1 works well with morphea, urticarial pigmentosa, atopic dermatitis, dyshydrotic dermatitis, subacute pruigo, and systemic lupus erythematosus. These diseases are treated by UVA rays because the wavelength is longer, which means there is less energy delivered to the skin and the greater penetration of photons (Dahl, 2012). Dermatologists even use sunbeds with higher intensity than regular tanning beds in their offices. For example, Windsor Dermatology uses four different types of light therapy to treat the skin condition psoriasis. One type of light therapy is that of UVA. The anti-inflammatory properties of ultraviolet light aid in slowing the growth of psoriasis effected skin
Stock issuance costs were recorded as a reduction in paid-in capital and are not considered to be a component of the acquisition price.
Electrotherapy is a range of beauty treatments that use electrical currents passed through the skin to produce several therapeutic effects. In this report I have researched and written
People with this condition are requiring a careful medical management to stay healthy and avoid complications of the illness and often require blood transfusions during significant illness or pregnancy (Children's Hospital Boston). Beta Thalassemia major originally called Cooley's anemia, is the most severe form of beta Thalassemia. It is caused by significant mutations on both of the beta chains. Patients with this illness require frequent blood transfusions to survive. They also require chelating therapy to remove excess iron that can build up in their bodies and cause extensive damage (Children's Hospital Boston).The symptoms of this type include fatigue and weakness, pale skin or jaundice, protruding abdomen with enlarged spleen and liver, dark urine, and abnormal facial bones and poor growth (Clinaero, n.d.).
Newborn jaundice is a condition marked by high levels of bilirubin in the blood. The increased bilirubin causes the infant's skin and whites of the eyes (sclera) to look yellow.
One way in which adjustments have occurred inside the coverage of incapacity issues inside the media is thru the terminology used. Disabling language is described by way of: “language that (a) perpetuates myths and stereotypes approximately people with disabilities, (b) uses nouns in place of adjectives to explain humans with disabilities, or (c) uses demeaning or old words or terms in reference to humans with disabilities.” The disabling language used inside the media has “the potential to affect nearly everybody with an incapacity and the insults are probably to be perpetrated by practically every man or woman in our society.” Todd Gitlin in The Whole World is Watching: Mass Media in the Making and Unmaking of the New Left explains media
Haemoglobin has complex quaternary structures. The normal adult haemoglobin (Hb) molecule contains two alpha-globulin chains and two beta-globulin chains. In foetuses and infants, the haemoglobin molecule is made up of two alpha chains and two gamma chains, but as the infant grows, the gamma chains are gradually replaced by beta chains, forming the normal adult haemoglobin structure. Foetal haemoglobin can bind oxygen more readily. This means the developing foetus can ‘steal’ oxygen from the mother through the bloodstream at the placenta.
In “Overusing the Bully Label” (Los Angeles Times, March of 2013), author, school administrator, and clinical social worker Susan Eva Porter suggests that adults commonly define minor difficulties that children have with one another as “bullying”. Porter begins by stating two examples of bullying that went extreme once the parents got involved, then shares how the extreme situation made the parents seem like heroes/victims, even though they were the ones escalating the situation, and then insists that "We do have a problem, but it's not with our children. It's with us, the adults.”. Susan Porter is trying to get the point across that in order to fix the situation on hand with bullying we need to stop labeling the kids that were mean once or twice as “bullies” and the kids on the other side of that aggression as “victims”, because once they are labeled they will start to believe they can't change. Porter wrote this article to Los Angeles Times, and throughout the article she tries to relate to the audience with stories of past proof of parental influences intensifying the situation along with stating her expertise in the field of working with children. The article tries to prove her stance that the cause of bullying is started by the students, but is effected by the adults/parents in today’s society.