Parkinson'S Disease, Also Known As Pd, Shaking Palsy, And

Parkinson’s Disease (PD) is a common idiopathic neurologic disease that affects nearly 1-2% of individuals over the age of 50. It is a slowly progressive disease with a life expectancy of 15 years following the initial diagnosis (Duffy, 2013). Having relatives diagnosed with PD increases the likelihood of being diagnosed with PD. In fact, one third of individuals with two or more relatives diagnosed with PD will likely acquire the disease (Duffy, 2013). Other possible causes may include unidentified environmental toxins, such as herbicides and pesticides.

PD is the second most common neurodegenerative disease featured pathologically by the progressive loss of dopaminergic neurons in the substantia nigra. The typical symptoms of PD include slowness of movements (bradykinesia), muscle stiffness (rigidity), tremor, and balance disturbance. Etiopathologically, PD is considered to be caused by the significant loss of dopaminergic neurons in the substantia nigra pars compacta and the subsequent dopamine depletion at the striatum. To date, there are only symptomatic treatments available for PD, particularly in the early stages of the disease. No therapy has been found that can cure or halt the progression of the disease.

Parkinson’s disease is a progressive disorder of the central Nervous system and affects both motor and nonmotor functions. parkinson 's is caused by a chemical imbalance within the brain. The brain produces a neurotransmitter called dopamine in the basal ganglia, which is structures linked to the thalamus in the base of the brain. If the Dopamine, Basal ganglia and Thalamus does not function properly then causes major damage,. A person having less and less dopamine, the individual has less and less ability to regulate their movements, body and emotions. Although there is no current cure available for Parkinson’s disease, the debilitating conditions can be lessoned through education, therapy, and a variety of treatments to improve their quality of life on the National Parkinson Foundation website.

The cause of Parkinson disease, defined by Robert Hauser, who is an author of Medscape, is still unclear. Studies state that there is a combination of environmental and genetic factors for this particular disease. Approximately 10% of cases are currently genetic causes of Parkinson disease. Environmental risk factors such as use of pesticides, living in a rural environment, consumption of well water, exposure to herbicides, and proximity to industrial plants or quarries are commonly associated with the development of Parkinson disease (Hauser, 2016). In addition, according to Hauser, “genetic factors in Parkinson disease appear to be very important when the disease begins at or before age 50 years. In a study of 193 twins, overall concordance for MZ and DZ pairs was similar, but in 16 pairs of twins, in whom Parkinson disease was diagnosed at or before age 50 years, all 4 MZ pairs, but only 2 of 12 DZ pairs, was concordant.The identification of a few families with familial Parkinson disease sparked further interest in the genetics of the disease.

Although the etiology of idiopathic Parkinson's disease (PD) is unknown, it is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of ventral midbrain region [9]; [1]. Its prevalence is associated with age. Approximately 1% of the population is affected at 65–70 years of age, which increases to 4–5% in 85-year-olds [2]. Various epidemiological studies and pathological analyses have demonstrated that mean age of onset in sporadic PD, which accounts for about 95% of cases of Parkinsonism is 70 years [7]; [3]. Familial form of Parkinson’s disease is linked to genetic mutations and has prevalence rate of 4%. Familial Parkinson’s disease patients develop early-onset disease before the age of 50

At the same time, Parkinson’s is still quite sporadic in nature. Should there be a familial relation however, mutations in specific genes have been conclusively shown to cause Parkinson’s disease. Familial cases of Parkinson disease can be caused by mutations in the LRRK2, PARK2, PARK7, PINK1, or SNCA gene, or by alterations in genes that have not been identified. In most cases, people with these mutations will develop Parkinson’s

Parkinson’s Disease (PD) is a slowly progressing neurologic disorder that affects the brain’s ability to regulate motor function. Most patients are able to live for years with the disease. Although there is no available cure for PD, patients are typically successful in managing symptoms and maintaining a good quality of life.

Parkinson's Disease has caused problems for many people in this world and plagued the elderly all over the world.Parkinson's disease still puzzles doctors and the causes are unknown. It is known that it is a non-communicable disease and may even be hereditary. Parkinson's disease is thought to be caused by external factors.

Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.

Parkinson’s disease (PD) is a slowly progressing neurodegenerative disease that affects muscle movement and control, leading to severe limitations in daily activity and quality of life. Symptoms and signs of PD often appear around the age of 60, but can occasionally present in much younger people. Symptoms tend to fluctuate and intensify over time. Individuals often experience significant disability 10 to 15 years after they have been diagnosed with it. Common indications of PD include tremors on one side of the body when at rest, bradykinesia (slow movements) and stiff or rigid muscles.

Parkinson’s disease is also accompanied by dementia in some cases. Your thinking becomes difficult due to cognitive problems in the brain. Depression and emotional changes in your person may develop also. You may feel panicked, anxious, or even lose motivation to carry out your day. Symptoms like these can be cured with anti-depressants. Drooling may become an issue due to it being hard, or slowed swallowing.

Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,

Parkinson’s Disease is a very common disorder these days. Over 10 million people live daily with Parkinson worldwide. Parkinson’s Disease was named after an English surgeon James Parkinson who wrote a detailed description essay called Shaking Palsy in 1817. The average age for Parkinson’s Disease is between 45 to 70 years old but you can also have juvenile or young onset as well. Most common symptoms of Parkinson are tremors, bradykinesia or akinesia, or rigidity or stiffness, and balance disorder. Parkinson’s Disease doesn’t have a cure and the cause is unknown it could be a number of things genetics, environmental triggers, age, or gender. Parkinson’s Disease happens because the dopaminergic neuron dies and

Parkinson's disease is neurodegenerative brain disorder that affects the brain and nervous system. When someone get Parkinson's it slowly develops in most people who get the disease. PD or Parkinson’s Disease affects people when they start to reach 60 years old. When a person is diagnosed with Parkinson's disease the brain slowly stops producing a neurotransmitter called dopamine. The less dopamine a person has the harder it is to control their abilities to regulate their emotions and body motions. Imagine not having any control of your hands, legs, arms, and emotions… heartbreaking. There is currently no cure for Parkinson's disease right now but with your help and donations made out to the michael J. Fox

Parkinson’s disease or PD is classified into idiopathic Parkinson’s disease, parkinsonism due to identifiable causes and parkinsonism in other neurodegenerative disorders. True Parkinson disease is classified into two subclinical groups. One group demonstrates postural instability and gait disturbances as dominant symptoms whereas the other group exhibits tremor as the prominent feature (O’Sullivan and Schmitz, 2007).