Opioids And The Opioid Receptor Essay

Opioids are prescription drugs such as oxycodone, hydrocodone and methadone just to name a few. Opioids are

The opioid crisis was caused by a variety of factors, but the main reason why these drugs are in the spotlight is because of the actions of the drug manufacturers. In order to fully understand the spark of the opioid crisis, it is imperative to understand what makes these drugs so potent. Writer and crime journalist Sam Quinones states that opioids are synthetic drugs. Naturally sourced drugs, known as opiates, are derived from the opium poppy plant. However, experts use both of these terms interchangeably. The use of opioids grew around the late 90s, and legally, most people used these drugs for pain relief. However, the people that were using these drugs had little information as to how addicting opioids actually were. In fact, opioids are

So how do opioids work and what makes them so addictive? We all have millions of pain receptors throughout our body called nociceptors that send information about pain to our brains. These pain receptors are on our skin, within our organs, and our spinal cord. Opioids are given for pain because they block the signals from the nociceptors to our brain. In addition to this, opioids cause a sense of euphoria which is the “high” that accompanies the medication (Healthcare Triage, 2016). Our bodies actually produce their own opioid chemicals that many people know of as endorphins. However, long-term use of opioids can make the body stop producing endorphins which can lead to dependence on medications (National Institute on Drug Abuse, 2014). The way people take or abuse these drugs varies as well. Opioid pills such as hydrocodone or oxycodone are taken by mouth while heroin is typically injected. However, people that abuse the drugs are now crushing the pills to snort or inject which increases the intensity of the “high.” This method is also more dangerous because the risk of respiratory

The opioid epidemic in America continues to grow at an alarming rate with no end in sight. All narcotics are derived from the opium poppy plant and then manufactured into different forms of drugs such as morphine, heroin, and other pharmaceutical and synthetic opioid drugs sold on the market for pain. Opium derived drugs block and suppress pain by binding to and stimulating the natural receptor sites for endorphins found in the central nervous system of a user’s brain. Patients who are prescribed narcotic drugs can quickly become addicted to the drugs because their body’s will stop producing endorphins and instead

Opioids are drugs that come from opium. Opium is the dried latex which comes from the opium poppy seed. These drugs create an euphoric effect on the brain. They attach to receptors in the brain to release opium. There are four classes of opioids. Endogenous opioids which the body release on its own at moments of joy. Opium alkaloid, semi-synthetic opioids, and fully-synthetic opioid which are all human made chemically in labs.

Oxycodone is the main drug I am concentrating on even though there are many opiates or schedule II drugs that are considered Opioids. Oxycodone was first created as part of an effort to find non-addictive alternatives to morphine and heroin, which were commonly used in medicine before World War I. Oxycodone is an opioid analgesic, ?Pain Killer? that is most often prescribed to control moderate to severe pain that must not be used with other medications. It is a slightly synthetic opiate that was created in 1916. The chemicals found in Poppy plants also make as morphine and heroin. Opiate:?A drug (such as morphine, codeine or heroin) containing or made from opium or the opium poppy, used to alleviate pain, or induce sleep or euphoria. ( A Forever Recovery. 2014. Web. 10 Mar. 2016). Opioid:?A synthetic or semi-synthetic substance producing an opium-like effect, often prescribed for the alleviation of moderate to severe pain; a prescription painkiller in the opiate class.

Opioids, otherwise known as prescription pain medication, are used to treat acute and chronic pain. They are the most powerful pain relievers known. When taken as directed they can be safe and effective at managing pain, however, opioids can be highly addictive. Ease of access helps people get pain medications through their physician or by having friends and family get the medication for them. With their ease of access and being highly addictive the use and misuse of opioids have become a growing epidemic. Patients should be well educated on the affects opioid use can have. More importantly instead of the use of opioids, physicians should look into alternative solutions for pain management. While pain medication is helpful with chronic pain, it is also highly addictive, doctors should be more stringent to whom and how often they prescribe pain medication.

Endorphins act as the body’s natural pain killers and lead to elevated moods and less perception of pain. The endorphins are primarily synthesized in the pituitary gland and are released when the body is under stress, or in pain. The endorphins will attach to opiate receptors (pain receptors) and dull pain. Endorphins are very positive, being released in exercise and helping with depression. However, the use of opioid medications, such as morphine, can lead to a deficit in the natural production of endorphins in the body and can lead to withdrawals and

Opiates are derived by opium. Opium is a gummy substance collected from the seed of the opium poppy. This

What are opioids? Opioids are a drug that heads to the nervous system of the body to relive an individual from pain. an example of an opioid would be morphine. Inviduals can get addicted to opioids (morphine and other pain relievers) and start frequently using them.

      As well as killing pain, moderate doses of pure opioids produce a range of mild effects. They depress the activity of the nervous system, including such reflexes as coughing, breathing and heart rate. They also cause widening of the blood vessels, which gives a feeling of warmth and reduces bowel activity, which causes constipation.

Opioids are drugs that act on the nervous system to relieve pain. Using them continuously and abusing can lead to physical dependence and withdrawal symptoms. They come in different forms such as tablets, capsules and even liquid.

For thousands of years, opiates have been used in the treatment of pain. Opium is believed to have been discovered 6000 BC, and since then, it has had a huge impact on both medicine and the recreations of those seeking euphoria. More recent than the ancient discovery of natural opium are the derivatives of opium, such as the alkaloids morphine, codeine, and thebaine. From these alkaloids, semi-synthetic opiates can by synthesized, such as hydrocodone, and oxycodone. Synthetic opioids are also quite prevalent, which include fentanyl and tramadol. Opium can also be processed into heroin, a morphine derivative. As advancements were made in science and engineering to allow for a wider distribution and usage of opiates, the problems of dependence and overdose also increased drastically. According to Hart and Ksir (2013, p. 302), the invention of the hypodermic needle for intravenous administration of morphine and other drugs allowed for a much faster and more potent dose of the drug. With this increased potency came an increase in the possibility of a recreational intravenous user to overdose. Hart also mentions that some of the wars surrounding the era of the synthesis of morphine may have contributed to the rise of morphine, seeing as a medic soldier’s motto was always “first provide relief” (2013). This relief-driven attitude and extensive use of opioid analgesics in medicine during the time, in addition to the large amount of patent medicines and remedies on the market may

Opioids are pain relievers that bind to opioid receptors on nerve cells throughout the body. They produce feelings of euphoria, tranquility and sedation. However, opioids are “considered the most harmful of all illicit drugs” (Amato et al., 2005, p.321).

“More than 16,600 people a year, die from overdoses of drugs, including Methadone, Morphine, and Oxycodone (OxyContin) and Hydrocodone combined with Acetaminophen (Lortab and Vicodin)” stated Consumers Report. The drugs listed above are all examples of Opioids. They are individual drugs that launch endorphins to the central nervous system which controls pain and relieves the severity of pain felt or silences it. Opioids also generate a sense of exhilaration and a calmness which is a product of the Analgesic effect. That feeling is one of the main reasons why people abuse opioids, they