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Nova's Film, Cracking Your Genetic Code

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Genetic testing is a medical test of one’s DNA that identifies changes in chromosomes, genes, or proteins. The results of a genetic test can confirm or rule out a suspected genetic condition which can help determine an individual's chance of developing or passing on a genetic disorder. In addition, knowing one’s genetic code can help individuals improve their wellness, prevent the onset of diseases they are at risk for, or lessen the harmfulness of diseases they do contract. NOVA’s documentary on PBS, “Cracking Your Genetic Code” demonstrates what exactly genetic testing is, how genetic testing is performed, and in addition the film showed stories about some individuals that have benefited from these special DNA techniques. The film plot focuses …show more content…

First shown is the story of the twins Noah and Alexis Beery, who are deeply affected with a rare disease that sort of mimics cerebral palsy. Through genetic testing, doctors discovered that the twins could be treated with the drug, dopamine. By sequencing their entire genome, the twin’s lives were saved. On the contrary, the film shows the story of Michael McCarrick, whose lungs were destroyed from years of suffering from cystic fibrosis. After researchers identified the gene involved in cystic fibrosis, it took decades to find ways to build the faulty protein responsible for the serious illness. There are two drugs, including one called Kalydeco, that offer a small number of patients hope that they will not have to endure a lung transplant. Though, it may be years before effective drugs are available for a wider population. The experimental drug that McCarrick took, Kalydeco, and other CFTR modulators are therapies designed to correct the function of the defective protein. Unfortunately, the drug was not able to save McCarrick, the damage to his lungs proved too great, and he died two months after the video was made. These examples show how unpredictable genetic testing can be. On one hand, it can be a huge advantage and save people’s lives within a few months, but on the other hand it can be years before someone can be cured, and before they know it it’s too

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