Vitiligo has always sparked my interest because the causes behind this rare appearance are bewildering. Vitiligo causes an individual to loose pigment in his or her skin, but is not deadly. Loss of pigment is caused when melanocytes die. Oddly, vitiligo showcases no other symptoms and researchers are baffled by why the cells die. Although there may be a correlation between non-segmental vitiligo and auto immune diseases. Diagnoses of vitiligo vary and display in different parts of the body such as the hair, eyes, mouth and skin. Two types of vitiligo exist and each has a different severity. Segmental targets a specific part of the body such as a leg, arm or face and begins at an early age. Eventually segmental vitiligo stops spreading after
Vitiligo is a chronic skin disorder that affects the pigmentation of the skin. Pigment is what gives the skin color and is produced by cells called melanocytes. In the disorder, the body attacks the melanocytes resulting in the loss of color in patchy areas. When the color is lost, the affected area becomes a white irregular shaped patch on the outer layer of the skin. Vitiligo can affect a very small portion of the body or affect up to fifty percent of the skin. The most common areas of the body affected by the disorder include the hands, feet, arms, face and sometimes the genitalia. This illness can be treated but it cannot be cured
Melanin, the major pigment responsible for skin, hair, and eye coloration, is synthesized in cytoplasmic organelles called melanosomes. Melanosomes are the cellular site of synthesis, storage and transport of melanin pigments, and are found in melanocyte cells. Mutations in genes responsible for the necessary melanocyte proteins to make melanin pigment result in a reduction or absence of melanin pigment, a condition known as oculocutaneous albinism. Oculocutaneous albinism type one (OCA1) is a genetic deficiency associated with 0-10% of normal melanin production in the skin, hair, and eyes. They’re two subtypes of OCA1, OCA1A and OCA1B. Individuals
Vitiligo is a common acquired skin disorder characterized by loss of pigmentation that results in hypomelanotic macules. Typically, the disease has an unpredictable course in which, due to unknown triggers, there is burst of activity with progress of the hypomelanotic lesions.1 Active state of vitiligo is defined as the extension of existing lesion and/or appearance of new lesion within the last year.2 Since reversal to original skin color is unusual, a rapid arrest of the spread of the lesion is the clinical goal in active vitiligo.1 In this scenario, tools that assess disease stability become important to determine the length of treatment. There is a need for development of a marker that monitors the disease prospectively, and sheds light
Vitiligo is a skin disease that produces a deficit of skin color in splotches. These white macules can have an effect on the skin of any body part. In extreme cases it can affect the interior of the mouth, hair, scalp, and even the eyes. The amount and degree of color loss is variable and erratic. Vitiligo can occur when the melanin producing cells die. The color of skin, hair and eyes is determined by the type and amount of melanin in the body. Vitiligo affects people of all skin tones and types, but it is most noticeable in people with a darker melanin or skin tone. It is neither a terminal nor communicable disease. Treatments are available to help even out the appearance of the skin, but there is no known cure.
Melasma Treatment Options that Work Melasma is a common skin condition that causes skin discoloration on the face. Statistics from the American Academy of Dermatology show that the disease affects more than 6 million Americans. Of those afflicted by the condition, 90% are women.
These forms of albinism are hard to be identified unless by gene testing, and are considered extremely rare.[4] Ocular Albinism primarily affects the eyes, and causes a lack of pigmentation in the Iris and the Retina, which is the light sensitive tissue in the back of the eye. [2]Pigmentation to these parts of the eye is crucial to normal vision. Individuals who suffer from this form of Albinism also face Nystagmus (involuntary eye movements), Photophobia (extreme sensitivity to light), and Strabismus ( when the eyes do not always look in the same direction).[4] Albinism is related to Hermansky-pudlak syndrome, which causes complete hypopigmentation, bruising, and problems controlling blood
This rare immune-mediated disease has to do with nerve and muscle transmission signals. Canines that have an excessive enzyme of Acetylcholinesterase in their body system, the communication between muscles and nerves breakdown. The ending of nerves release acetylcholine, which is known to relay impulses, in cases where receptors are limited, the impulse doesn’t make contact with its receptor, so generally, muscle weakness results. Environment, hormones, breed of canine, congenital and inherited conditions all have roles in this disease. Acquired is auto-antibodies that eradicate the receptors for acetylcholine. There is also diagnosis where a tumor in the thymus gland is present causing hypothyroidism as a secondary disease. Congenital is
Every body has a different amount of pigment in their skin , that's how we are all different .
Melasma is caused due to an over production of melanin. Melanin is the substance that imparts color to the skin. The exact cause for this type of hyperpigmentation is not known. However, the main four factors that contribute to melasma are hormone, genetics, skin inflammation and sun exposure. Intense exposure to sun can worsen the problem. Pregnancy and menopause also can trigger melasma. It
Vitiligo is a skin disorder which causes skin to lose its color. The skin depigmentation is a result of the loss of the melanin in your skin. Melanin protects your skin from the ultraviolet rays from the sun. It is produced by cells in the epidermis layer of the skin called melanocytes. If the melanocyte cells were to die, the skin would become white and have no color. Many people with Vitiligo develop small patches where the skin will become lighter or turn completely white. Others may have a wide loss of skin color. This loss of skin color can happen anywhere on the body but it generally begins on the feet, face, hands, and forearms. The main effect of the disorder is loss of skin color. Vitiligo does not cause any irritation, pain, or swelling.
Vitiligo is a skin disease where an individual loses their pigmentation when the pigment producing cells are attacked and destroyed (AOCD, n.d.). Vitiligo is also known to be an auto-immune disorder where certain white blood cells direct the destruction of the melanocyte (AOCD, n.d.). Melanocytes are cells that give us our skin and hair color (AAOD, n.d.). Vitiligo affects any individual no matter their ethnic origin or sex. Individuals often notice that they have the skin disease before they reached the age of 20 which is often notice on individuals with darker skin. Common areas that vitiligo would normally start would be on an individual’s hands, feet, or face (AOCD, n.d.).
Life holds many obstacles. They are put there to challenge us physically and mentally in the hope that we become a better person. Some people face more demanding obstacles. When I was about six years old, blotches of white starting appearing on my skin. They were most abundant around my ankles, knee, hips, and elbows. My parents got worried and took me to see my doctor. I was diagnosed with vitiligo. Vitiligo is a chronic skin disease that results in loss of skin pigment. Once my parents heard what I had, they made the connection. Autoimmune disorders run in the family and many of my relatives also had vitiligo. This condition is incurable, but my doctor gave me a prescription to try to reduce the enlargement of the areas. After several months,
They are mostly divided into two types. One as described which affects the pigmentation of the skin, hair, and eye is known as Oculocutaneous Albinism (Ock-you-low-kew-TAIN-ee-us); the second which is called Ocular Albinism. This type of Albinism affects the eyes rather than pigmentation of the skin and hair. There are four types of Ocular Albinism.
The American Academy of Dermatology claims that there are over 50 million people struggling with acne. Countless acne brands and treatments propose flawless skin fast by the use of advertisements. The United State Library of Medicine classifies acne as the most common skin disease in America. It occurs when oil, dirt or bacteria clog the pores in the skin. Acne Resource Center Online states that an estimated 85% of people ranging between 12 and 25 will experience an acne breakout and over 40% of people suffering with acne do not feel the need to treat it. Treatment for mild and severe acne can be cured by a visit to the dermatologist. Untreated acne can lead to permanent scarring and unnecessary damage to the skin (Layton, Henderson & Cunliffe
Vora et al. (2014) noticed that the commonest site to be affected was lower limb, followed by upper limb, face, trunk, and genitals. The commonest morphological pattern observed was vitiligo vulgaris, other patterns noticed were acrofacial, segmental, universal, and mucosal. Bilateral distribution was a common observation among patients and most of patients showed more than