Myeloid Leukemia Cancer

The primary pathophysiological etiology for signs, symptoms and laboratory findings in 4 year-old John’s case study are secondary splenomegaly as a result of primary Acute Lymphoblastic Leukemia (ALL). Because of its proximity to

Leukemia is a type of cancer that sadly causes around 25,000 deaths in the U.S. each year. The area that it affects is the blood and the bone marrow and like most or all of the types of cancer in the world if not taken control of early it will most likely kill you.

There are two types of leukemia in children; acute and chronic. Acute is fast growing leukemia. Within acute leukemia are three categories: acute lymphocytic (lymphoblastic) leukemia (ALL), acute myelogenous leukemia (AML), and hybrid or mixed lineage leukemia. Acute lymphocytic (lymphoblastic) leukemia (ALL) is the most common type of childhood leukemia and develop from early forms of lymphocytes, also known as white blood cells. Specifically, three out of four childhood leukemias are ALL (About Childhood Leukemia). Acute myelogenous leukemia (AML) starts from the myeloid cells that create blood forming cells such as white blood cells (except for lymphocytes), red blood cells, and platelets (About Childhood Leukemia). Hybrid or mixed lineage leukemia are rare forms of childhood leukemia, but can be treated like ALL and AML. On the other end of the spectrum is chronic, or slow growing, leukemia. Chronic leukemia is difficult to treat and are more commonly found in adults than children. There are two types of chronic leukemia: chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL). Chronic myelogenous leukemia (CML) is not commonly

An evaluation typically includes a complete blood count (CBC), a visual look at the blood cells placed on a glass

Cytogenic analysis – Microscopic examination of lymphocytes to look for structural changes or changes in number of chromosomes.

Blood protein testing: A test to examine various proteins in the blood can aid in detecting certain abnormal immune system proteins that are sometimes elevated in people with multiple myeloma ("Leukemia Home Page - National Cancer Institute").

In the human body there is three types of blood cells: white blood cells, red blood cells, and platelets. White blood cells are the cells that help fight the infections that occur in the body, red blood cells carry the oxygen throughout the body, platelets help the blood clot up. These three types of blood cells are created in the bone marrow, the soft tissue inside bones, billions of new bloods cells are created everyday and most of the cells that are produced are red. When an individual has leukemia the body is creating more white blood than what it should and they then do not mature right and the body has trouble getting rid of them making them live longer than their normal lifespan. These abnormal cells are now known as leukemia cells. When the abundance of cancerous cells spread throughout the body it cause problems with vital organs functions such as bleeding, bruising, red blood cells being able to deliver oxygen throughout the body, the body can no longer fight infections as well.

• Bone marrow aspiration. For this test, a needle is put into your bone. Cells from the bone marrow are removed through the needle. The cells are then examined under a microscope.

Mixed lineage leukemia (Mll) are a family of catalytic enzymes in humans which contain a highly

Chronic myeloid leukaemia (CML) is one of the most dangerous bone marrow diseases with an initial chronic stage lasting for 3-5 years. It changes to a very fast phase called accelerated phase and then to the blast phase in which it leads later to death1. Besides (CML) is a type of cancer that affects the blood cells by raising the level of the immature white blood cells (leukocytes) in the bone marrow and which leads later to circulate in the blood stream. These crowded immature blood cells do not perform their vital role in defending the body against infectious organisms properly, and that leads to leukaemia disease progression.2, 3

One of the types of leukemias is acute lymphoblastic leukemia (ALL) an acute form of leukemia that is cancer of the white blood cells. It is characterized by the accumulation of malignant immature lymphoid cells in the bone marrow called lymphoblast. It is mainly a childhood disease, occurring rarely in adults thereupon it’s been reported to be the most malignancy in children, representing one third of pediatric

Acute leukemia is fast-growing, where the leukemia cells begin to replicate quickly before any immune functions have developed, and it gets worse at a faster rate than chronic leukemia. One type of acute leukemia is Acute Myeloid/Myelogenous Leukemia (AML). AML causes the body to produce a large number of white blood cells, also known as myelocytes, that are unable to efficiently fight

disease. Nowadays, there are improvement of AML in 35 to 40% of adult patients who are ≤ 60

Leukemia is a cancer that attacks a persons’ blood. This is where the patients’ white blood cells grow abnormally and mutate, blocking the growth of normal blood cells. Leukemia can cause bruising that seems to come from nowhere and a person cannot remember where they got them from. White blood cells are very important to immunity so having this cancer can highly decrease someone’s immunity to anything from the common cold to a viral infection. If Leukemia is not caught in time, like all cancers, it can be deadly.

There are many different types and variations of leukemia, and not all types have singular, concrete causes associated with them. One of the four most common types of leukemia, acute myeloid leukemia, is characterised by the unregulated growth of blasts which