My Sister's Keeper: Acute Promyelocytic Analysis

This movie called My Sister’s keeper is a film that is all about a couple’s life that has a daughter named Kate. Kate was diagnosed with promyelocytic leukemia. Promyelocytic leukemia (PL) is a malignancy of the bone marrow in which there is a lack or insufficiency of mature blood cells in the myeloid line of cells and an excess of immature cells called promyelocytes. PL is due to a translocation (an exchange of chromosome material) between chromosomes 15 and 17 which is symbolized t(15; 17). This translocation is not a mere marker of PL. It is the cause of PL (MedicineNet, n.d.). Gordon’s functional health assessment pattern was use in this presentation. The patient’s culture, geographic, religious, ethnic or spiritual and sexual concerns

Seeing that Kate has leukemia, the only way to save her is for her parents to have a genetically modified baby to be a perfect match donor for Kate. When Anna ponders about herself donating to Kate, she says, “It made me wonder, thought, what would have happened if Kate had been healthy? Certainly, I would not

There are two types of leukemia in children; acute and chronic. Acute is fast growing leukemia. Within acute leukemia are three categories: acute lymphocytic (lymphoblastic) leukemia (ALL), acute myelogenous leukemia (AML), and hybrid or mixed lineage leukemia. Acute lymphocytic (lymphoblastic) leukemia (ALL) is the most common type of childhood leukemia and develop from early forms of lymphocytes, also known as white blood cells. Specifically, three out of four childhood leukemias are ALL (About Childhood Leukemia). Acute myelogenous leukemia (AML) starts from the myeloid cells that create blood forming cells such as white blood cells (except for lymphocytes), red blood cells, and platelets (About Childhood Leukemia). Hybrid or mixed lineage leukemia are rare forms of childhood leukemia, but can be treated like ALL and AML. On the other end of the spectrum is chronic, or slow growing, leukemia. Chronic leukemia is difficult to treat and are more commonly found in adults than children. There are two types of chronic leukemia: chronic myelogenous leukemia (CML) and chronic lymphocytic leukemia (CLL). Chronic myelogenous leukemia (CML) is not commonly

The Ayala Case presented in Case 2 from Chapter nine explains that Anissa “was diagnosed with chronic myelogenous leukemia (174),” at the age of sixteen. None of Anissa’s family members or candidates from the National Marrow Donor Program was a match with her bone marrow. The only option left was for Anissa’s parents to conceive a child with compatible bone marrow. “…The odds of having a child that could save Anissa’s life (175)” were only 6.4%. Against the low odds, Anissa’s parents had a child named Marissa-Eve that was compatible with Anissa’s bone marrow. At fourteen months, Marissa-Eve’s “bone marrow was used in a transplant to save Anissa’s life. Anissa’s life expectancy surpassed the original numbers she was given, which was three to

Response: If I were in the same situation Anna was in, I would do everything I can to save my sibling's life, even if my sick sibling tells me to stop helping them to get better. I would not listen to them, and continue helping them get better. My siblings matter to me and I wouldn't want to see them out of my sight ever. If one of them gets severely sick, I would absolutely do whatever I can to bring them back to their normal health. It is revealed to us in chapter one (Monday) that Anna is an allogeneic donor, meaning she is a perfect donor for her sister Kate who has acute promyelocytic leukemia. She is the only hope for Kate to get better. Anna would constantly give blood to Kate in order to save her life. She also gave her a bone marrow. Kate has realized that Anna has been sacrificing a lot for her

The Revised Atlanta Classification now divides AP into three classes of severity. It is mild, moderately severe or severe, whereas the previous classification referred only to mild and severe AP. Factors that determine the severity of disease include the presence of transient or persistent organ failure, and local or systemic complications. Mild AP occurs in the majority of patients with AP. It is characterized by the absence of organ failure, local or systemic complications. These patients are usually treated conservatively, do not often require imaging and may be discharged in the early phase. Symptoms usually resolve within 1 week. Moderately severe AP, this additional severity subtype was added in the most recent revised Atlanta Classification. It includes patients with AP and transient organ failure less than 48 hours and/or local complications. Mortality is much less than in those with severe disease. Severe AP is characterized by persistent organ failure for more than 48 hours. POF may involve one or multiple organs. Severe disease is associated with a mortality of 36 to 50% (17).

The character of Sara is most adamant that it is in Anna’s best interests to act as a donor for Kate. However I do not think she meant for Anna to be at the mercy of her sister. I think she was only intent on doing what had to be done to keep her family intact by preserving the life of Kate. Sara believes that the social, emotional and psychological best interests of a person depend upon the happiness in the family in which they grow up in. This gives the idea that Anna’s best interests and welfare are closely tied to those of her family, who

Leukemia is cancerous disease that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the blood-stream (National Cancer Institute, 2008, para. 1). It is one of many complicated cancer diseases that affect all ages and have very negative outcomes if not treated properly, and on time. Within the disease are several different types that affect according to how quickly the disease develops and attacks the body. It could be classified as chronic leukemia, which has a slow progress of getting worse or acute leukemia which usually gets worse quickly. The types of leukemia also can be grouped based on the white blood cell that is affected (National Cancer Institute , 2008, p. 1).

Other treatment options include various modes of chemotherapy, the treatment of support, administration of drugs Antihemorrhagic, therapies chelators , transfusions and antibiotics to reduce the spread of infections. In recent years, finally, it was also introduced the use of immunomodulatory and immunosuppressive agents.

My Sister's Keeper is the story of Anna Fitzgerald, who by the age of thirteen has undergone many blood transfusions, numerous surgeries, and multiple bone marrow transplants. “Most babies are accidents, not me. I was engineered, born to save my sister’s life.” At the beginning of the movie Anna explains that she as conceived to be a donor for her sister, Kate. Kate is a 16 year old with renal failure due to a very rare form of leukemia. The girls' parents expect Anna to donate her kidney to help her sister. Instead of donating the kidney, Anna files a lawsuit against her parents for the rights of her own body so that she could not be forced into the surgery against her will. This causes mixed reactions between Anna’s parents, Brain

• A bone marrow sample helps find signs of cancer that could be affecting blood production.

My Sister’s Keeper is about a family who conceives a child strictly for the use as bone marrow donor for her gravely ill older sister. Kate is diagnosed with Acute Promyelocytic Leukemia at the age of two. As their doctor tells them of their options, he asks Sara and Brian, the parents, have they thought about

Anna knows that without her, her older sister would be dead. Anna is always having to donate many different things to her older sister. Things she may not need to necessarily live, but things she may and may not be uncomfortable with donating to her sister. Constantly donating blood to you older sibling could be very awkward, while others may think there is absolutely nothing wrong with it. The problem they have is different considering the circumstances they are put under. Especially when finding out our sibling need one of your lung, or they will die. Though you have no legal obligation to donate that lung to your sibling, you would want to do the right thing, But you could imagine Anna’s problem, she has always donated things to her older sister Kate, and she may just be tired of donating things to her and sharing things with her. Eventually she probably begins to wonder is it worth it, but knowing it is the right thing to do, she continues to donate things to her sister. Besides this problem, there is also the fact that Anna knows she was created just so there would be someone close enough to Kate that would be able to save her life in different

I believe Anna was right to listen to Kate because she passed away knowing that she was not going to live and was not going to be put someone’s life in danger to save her own. I believe what she did was right because Anna was brought into the world to be a genetic match for her older sister, Kate, who suffers from acute leukemia. Her sister's dependency on her, Anna was unable to live the life she wants. Anna in and out of the hospital constantly, she cannot take part in extracurricular activities such as cheerleading or soccer. Knowing that she will have to donate one of her kidneys to her sister, Anna sues her parents for medical emancipation and the rights to her own body. Believing that she would not survive the surgery, Kate wants to die. Anna wins the case, and due to her sister's wishes does not donate her kidney. In conclusion , it shows that Anna not only fulfilled her sisters wishes, but also stood up for herself because she did not want to go under the knife, and go through a painful process not knowing what could possibly happen to her. It not only shows a symbolic sisters role, but also elaborates on equality for justice, and personally rights. Therefore, I do believe what she did for herself and her sister was the right thing to do because she did not deserve to go through such a difficult

Anna Fitzgerald, the youngest in her family, is a genetic match to her older sister, Kate, who has APL, a rare form of leukemia, and is her donor. Anna is thirteen and has decided to file a lawsuit against her parents for rights to her own body. She does this because she claims to not want to donate a kidney to her older sister. Being in the same family as a cancer victim tends to take the spotlight off of you, and this is how Anna and Jesse feel, which is what she calls being invisible. However, she believes the lawsuit may allow people to start ‘seeing’ her, and see that she is not the obedient, younger daughter everyone thought she was and that she isn’t just extra lymphocytes, bone marrow, and organs for her sister. soon learns that making