Melanoma Research Paper

The largest organ of the human body is your skin. It is your body’s first line of defense against infections, injuries, heat, and sunlight. It also helps in controlling the temperature of your body and getting rid of the excess water and salt by sweating it out. Skin cancer is also known as cancer of the sun. Excessive amounts of ultra violet lights affect your skin in negative ways, possibly leading to Melanoma skin cancer. Melanoma is the most serious type of skin cancer there is and can often times be fatal (McClay).

Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and

Superficial spreading melanoma: the most common type of melanoma carrying up to 70 percent of all the melanomas in the world. It is common in the young people and as the name suggests it spreads across the top layer before penetrating deep inside the skin.

Those who may spend the vast majority of their week indoors but go to the beach on the weekends or outside on vacations are much more likely to develop a skin cancer than those who spend regular time outdoors. There are also risk factors that put some people at a higher risk for developing skin cancers, as well. These include:

Melanoma is a skin cancer derived from melanocytes and is considered to be the most common fatal malignancy of young adults. About 60% of melanomas harbor a mutation in BRAF, a serine/threonine protein kinase involved in promoting MAPK signaling and cellular proliferation. Of these, 90% harbor the BRAFV600E mutation. To combat this disease, the BRAF inhibitor, vemurafenib, was approved in 2011 to treat late-stage melanomas that are driven by the BRAFV600E mutation. Despite the immediate, positive clinical response to the drug, resistance develops after 7 months of vemurafenib treatment. Significant research effort has been devoted to understanding the origin of this drug resistance, but few studies have examined the fate of individual cells

Melanoma was the major focus of our project. Our initial goal throughout this entire project was to inform the student body about melanoma as well as make an attempt to prevent sun exposure. We planned to find a way to see how much the students at St. Scholastica knew about the dangers involved in being in the sun. We planned to create two surveys and a pamphlet to help find the student body’s knowledge about this dangerous disease. Our group first started off giving out a survey that gave us a base model of how much the students already knew about melanoma as well as sunburn and sun exposure facts. We then proceeded to make a pamphlet that had useful information on it involving when to wear sunscreen, when to be out of the sun, and facts about melanoma. This was then slid under the doors of the residents of Somers hall. We purposely put out this pamphlet prior to going out on spring break in hopes that people would take in this information before they hit the beach. Being that the students got this information before they put their skin in danger of developing skin

Cancer treatment is one of the greatest benefits of image processing in the medical field. However Melanoma one of the most dangerous forms of cancer which leads to more casualties than any other form of skin cancer has very little light shed on its image processing models. Mostly inspections are done by the physicians visually and image processing is utilized only when the patient enters the late stages of its life cycle. The main source of information is usually gathered visually and in this master's thesis I shall develop a working android application using which a patient can monitor and examine themselves with just a mobile phone.

The most serious type of skin cancer is melanoma. Melanoma begins in the melanocytes and forms tumors that are usually brown or black. Any skin on the body can develop melanoma. The common places for melanoma to start are the back and chest of men and the legs of women while the neck and face are also common spots. Although it is uncommon, melanoma can also be found in the eyes and mouth. The skin is the main organ affected by melanoma but its is possible for the cancer cells to spread to internal organs. If melanoma is spread to the immune system, it can trick it to not destroy the cancer cells by use of immune cell proteins. Melanocytes are cells with pigment in them, that give the skin its color and are also the cells that become melanoma.

Cutaneous melanoma (hereafter referred as melanoma) is a worldwide public health concern. In developed countries melanoma ranks as the sixth most frequently diagnosed cancer overall [1]. In the United States, melanoma is the fifth most common cancer in men and seventh most common cancer in women [2]. The incidence of melanoma, the most commonly fatal form of skin cancer, is increasing faster than any other potentially preventable cancer in the United States [3-4]. World wide epidemiological data shows similar increases over the past years, with a leveling off in other countries [5]. Some researchers attribute the increase in the incidence of melanoma to a more scrutinized detection program [6-7].

Typically, people with fair skin, light colored eyes and hair, have freckles and burn easily instead of tanning are more likely to get malignant melanoma than anyone else. Although melanoma accounts for less than 2% of skin cancers, it is responsible for the clear majority of deaths from skin cancers (Tan, 2016). The American Cancer Society (2016) estimates that the current year about 76,000 new cases will be diagnosed and that there will be around 10,000 deaths due to this. Worldwide, the occurrence of malignant melanoma cases has been rapidly increasing, and it is doing so faster than any other cancer besides lung cancer in women. Queensland, Australia and Israel have the highest occurrence of melanoma in the world (Tan, 2016). Melanoma can affect anyone of any race or age it rarely effects children under the age of ten. The average age to be diagnosed with it is 57 years old and women usually get diagnosed at an earlier age then men, usually before the age of

Each year there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate, lung and colon. Skin cancer can be defined as abnormal developing in cells in the outer layer of skin. it can spread over the other cells skin, and it can be seen visually on the surface of the skin. Skin cancer is not like photosensitivity they both share some similar causes like exposing to UVR or exposure to sunlight for long period also they have similar visually effect such as red patches on the skin but they are totally different. Photosensitivity can be treated. However, some kind of skin cancer cannot be treated. Skin cancer has a three main types: malignant melanoma, basal cell carcinoma, and squamous cell carcinoma, and

The Gale Encyclopedia of Medicine defines malignant melanoma as “a type of cancer arising from the melanocyte cells of the skin.” The number of people diagnosed with skin cancer keeps rising every year. According to the Journal of School Health skin cancer is increasing by approximately 3.5% per year. Skin cancer has become the most common cancer, according to the World of Health. Skin health is often overlooked and more concentrated on society’s ideals of perfect tan skin rather than the health and protection of our skin.

Skin cancer is a skin related disorder, and it is one of the most deadly cancer in the world. Over the past three decades, more people have had skin cancer than all of other cancers. There are three types of skin cancer that affect people. Basel-cell skin cancer (BCC), squamous cell skin cancer (SCC), and melanoma. squamous-cell skin cancer (SCC) is the most common type of skin cancer while melanoma is the most dangerous type of skin cancer. Also, basal cell skin cancer (BCC) is very common. Skin cancer is a group of disease that arises from the skin. It often affects the people who go to the beach because of the ultraviolet radiation of the sun. In this essay, I will attempt to explain causes, symptoms,

Notably, skin cancer is known to be an uncontrolled growth of abnormal skin cells (similar to how every cancer functions but differs in types of cells and how it alters DNA sequences), and is mostly triggered by overexposure to ultraviolet light from solar radiations or tanning beds. Hereditary factors, weak immunes systems or others diseases also cause skin cancer which thankfully can be prevented. The three most common skin cancers are basal-cell cancer, squamous-cell cancer and melanoma.

C. Melanoma Skin Cancer is the most dangerous form of skin cancer, it kills one person per hour, these cancerous growths are most often caused by ultraviolet radiation from sunshine or tanning beds. These tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Often the first sign of melanoma is a change in the size, shape, color or feel of a mole.