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Malignant Fibrous Histiocytoma Case Study

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value about 0.71 + 0.15 x 10-3 mm2/sec (mean + SD) and four cases of malignant fibrous histiocytoma their mean ADC value was about 0.81 + 0.15 x 10-3 mm2/sec (mean + SD); thus our results are comparable to those of Oka K, et al (24), as the mean ADC value of the malignant soft tissue tumors reported in his study was 1.02 + 0.20 x 10-3 mm2/sec (mean + SD).
Also in the current study there were three cases of each of the following: undifferentiated round cell sarcoma and synovial sarcoma with mean ADC values: 0.52 + 0.20 and 1.02 + 0.30 x 10-3 mm2/sec (mean + SD) respectively; thus our results are consistent with those of Oka K, et al (24). In this study we encountered a case of malignant myxoid tumor (high-grade myxofibrosarcoma), its ADC …show more content…

Although there was no significant difference in the ADC value between benign and malignant myxoid tumors, in the contrary among non-myxoid tumors the mean ADC value for malignant tumors was significantly lower than that for benign tumors all ADC values for malignant non-myxoid tumors were lower than 1.235 × 10−3 mm2/s . These findings suggest that if an ADC value exceeds 1.235 × 10−3 mm2/s in non myxoid tumors the possibility of malignancy is low. Furthermore, these findings suggest that a low ADC value does not exclude the possibility that a tumor is benign. . In our study we obtained threshold value 1.235 x 10-3 mm2/s with 73 % sensitivity and 91.7% specificity where there is highly significant difference between benign and malignant soft tissue tumors. In the current study we encountered three patients with benign lesions, demonstrating low SI in DWI and very low ADC value similar to ADC values of malignant soft-tissue tumors, yet turned to be lipomas with mean ADC value 0.31 + 0.91 x 10-3mm2/sec and they were considered as false positive, and these results were consistent with those of

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