Levemir Essay

Insulin for diabetes was discovered in 1921 at the University of Toronto by Sir Frederick G. Banting, Charles H. Best, and JJR Macleod. James B. Collip subsequently purified it, and one year later on January 11, it was put to use on a young 14 year old boy named Leonard Thompson; a patient at Toronto General Hospital. Once the substance was delivered, it was found that the extract was so pure that he suffered an allergic reaction, and further injections were cancelled. James Collip worked for the next 12 days on improving the ox-pancreas extract, and the second dose given to Thompson on January 23 was completely successful. Prior to this, a type 1 diabetic would be put on a starvation diet, or be limited to a calorie intake of around 450 calories per day, and would only live a few extra months. Leonard Thompson lived another 14 years, until 1935 when he died of pneumonia at the age of 28.

Take the medication exactly as directed by the medical care provider. The recommended starting dose of Jentadueta is individualized; it depends on the doses of the medication you are taking. As earlier mentioned, before the doctor prescribes Jentadueta, you must be taking Metformin alone or with Linagliptin, but as separate tablets. The dose prescribed is taken twice daily (in the morning and evening), but with meals to reduce Jentuadueta side effects.

*Subcutaneous injection administration – With this injection, the medicine is administered directly under the skin. A common example of a medicine administered via this route is insulin. Medicines are injected in the fat layer beneath the skin.

Answer: The combination of Insulin as well as oral hyperglycaemic drugs may be prescribed for Diabetes because they help in lowering the blood glucose levels. However the primary treatment doesn’t consist of these drugs. The primary treatment comprises of Diet control, Physical activity and Weight control. If after following the primary treatment strictly, no improvement in the blood glucose level is achieved then medication is suggested for the same. Insulin helps in maintaining the blood sugar levels. Note that insulin is not to be taken orally because the acids and digestive juices in the stomach destroy it. It has to be injected under the skin only. Taking insulin leads patient to experience Hyperglycaemic condition. The Hyperglycaemic drugs helps our body to react appropriately with the insulin so that the insulin hormone is able to help transfer glucose from blood to the cells successfully.

Insulin is a crucial thing in a Type One Diabetics life. It is the only treatment for them. Not to confuse you, but insulin is no cure by any means. Their pancreas has stopped making insulin, so they must inject themselves with insulin several times each day in order to stay alive. They also must check their blood glucose levels at least every five hours throughout the daytime to make sure it does not go to high or low and before each meal. The only real treatment for Type Two Diabetics is eating healthy foods and exercising daily. They also must check their blood glucose levels regularly, but not near as often. Some people do take insulin for their Diabetes to help their pancreas produce a little more insulin, but it is only required if food, exercise and medicine (pills) are not working.

Lantus, a sterile solution of insulin glargine, does not require more than one injection per day and typically lasts about 22 hours for most people. But some people take two injections -. One in the morning and just before going to bed

Dosages of the drug vary from one extreme to another based upon the patients needs.

2000mg/day. If doses >2000mg/day are required, give in 3 divided doses (not to exceed 2500mg/day)

Adverse reactions to drugs are common and almost any drug can cause an adverse reaction.

Adverse reactions to this medication are migraine, speech disorders, rhinitis, sinusitis, hyperglycemia, elevated liver function, elevated serum creatinine level, pancytopenia, bronchitis, dyspnea, toxic epidermal necrolysis, anaphylaxis, elevated creatine kinase, generalized pain, and infection. Nursing considerations with this medication is to have the patient swallow the whole tablet and not to chew. Watch for aspiration while watching the patient take the medication. Educate the patient about the medication and inform them to notify a physician if bleeding

6 years to 11 years: 2.4 to 5 mL orally dosage 2 times a day .

Because of body weight, height and other factors, the dosage of insulin is different for evey person depending on their blood glucose level. Metfrormin is a drug common drug used for diabetes that is taken orally (by mouth). It is a small pill taken daily, and it also helps comtrol blood sugar levels.

Presently, leuprolide is administered by parenteral routes: 11.25- and 22.5-mg, 3-month depot intramuscular injection (Lupron Depot®) and 1-mg daily subcutaneous injection (Lupron®).

b.ii. The dosage will depend on the age, weight, and other health issues of the person.

Hence, it is rather difficult to obtain an effective and at the same time safe pediatric dose, as a linear reduction of the adult dose would not be considered a reliable approach. Even today, this is a great challenge as most drugs are not specifically approved for pediatric use and a dosage approximation becomes necessary. Pharmacometabolomics can improve the knowledge and understanding via a more accurate definition of drug response and the metabotype (metabolic phenotype) of a subject, which results from the interaction of several genetic, physiological, chemical and environmental influences.