Hashimoto’s Disease vs. Graves Disease
Anna Grochowski
Salter College
Anatomy and Physiology II
September 18, 2013
Dr. P. Wong
Hashimoto's disease can also be called chronic lymphocytic thyroiditis or autoimmune thyroiditis. An autoimmune disease happens when the body's immune system attacks it's own cells and organs instead of its normal job of protecting the body from infection. Hashimoto's disease specifically attacks the thyroid gland, causing inflammation interfering with the ability to produce thyroid hormones. (http://www.mayoclinic.org/diseases-conditions/hashimotos-disease/basics/definition/con-20030293) A large number of white blood cells also accumulate in the thyroid. These white
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Keeping the body in its healthiest form by diet and exercise is always a helpful additive though.
Hashimoto’s Disease compared to Graves’ disease:
Whereas Hashimoto’s is an under active or under developed thyroid gland, Graves’ disease is the opposite. Graves' disease is an immune system disorder that results in the overproduction of thyroid hormones, better known as hyperthyroidism. Although a number of disorders may result in hyperthyroidism, Graves' disease is a common cause. (http://www.mayoclinic.org/diseases-conditions/graves-disease/basics/definition/con-20025811)
What I’ve learned:
Living with Hashimoto’s has taught me that I need to be very careful in the way that I treat my body. Healthy diet and exercise is a great way to start taking care of yourself. Y ou also have to make sure you take your medication as prescribed. I know first hand how hard it can be if you miss a dose of levothyroxine or if you take it at the wrong time. Everything in moderation is okay, but when you have a disease you have to be extra careful.
References
http://www.mayoclinic.org/diseases-conditions/hashimotos-disease/basics/definition/con-20030293
http://www.webmd.com/women/hashimotos-thyroiditis-symptoms-causes-treatments
Graves ' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). The thyroid gland is an important organ of the endocrine system. The gland is located at the front of the neck above where the collarbones meet. This gland releases the hormones thyroxine (T4) and triiodothyronine (T3), which control body metabolism. Controlling metabolism is important for regulating mood, weight, and mental and physical energy levels. When the body makes too much thyroid hormone, the condition is called hyperthyroidism. Graves disease is the most common cause of hyperthyroidism and is most common in women over age 20. But the disorder can occur at any age and can affect men as well. Some of the symptoms of Graves diseases are
Hashimoto’s Disease is a chronic Lymphocytic thyroiditis also known as autoimmune thyroiditis. It is due to chronic inflammation; the disease is a failure of the thyroid gland. Hashimoto’s disease is the most common inflammatory disorder of the thyroid and the leading cause of having hypothyroidism. The name of the disease came from a Japanese surgeon named Hashimoto Hakaru. Hakaru first described the chronic disease as Struma Lymphomatosa in a pathology report in the year 1912. Hashimoto’s Disease is a genetic trait and found to be more common in women then in men; and commonly found in women between the ages of thirty to fifty years of age. Hashimoto’s Disease can be found in children too; in the first-degree relatives that have the disease is found to have an increased incident.
Hashimoto’s Thyroiditis can also come as an attack on the thyroid via an autoimmune disorder. The immune system can attack the thyroid; however, no one knows exactly why this
However Graves' disease is named after the Irish physician who described several cases in London Medical Journal in 1835. Graves' disease is also known as Parry's disease. In Europe, the disease is known as Basedow's disease. It is the most common cause of thyrotoxicosis (the morbid condition due to over activity of the thyroid gland).
Hashimoto's thyroiditis is an autoimmune disease where the body sees the thyroid tissue as an antigen, and therefore attacks the tissues which results in inflammation and eventual destruction of the thyroid gland (Burkhart, 2013). Hypothyroidism (an underactive thyroid gland) is one of the first clinical symptoms that lead doctors to diagnose Hashimoto’s (Mayo Clinic Staff, 2016). Other symptoms can include fatigue, weight gain, hair loss, and joint pain, among other things. As diet in America gets worse, autoimmune disorders rise. The food we eat is negatively affecting our bodies, so much so that they are becoming inflamed and rejecting those foods in the form of allergies. Nutrition plays such a vital role in
Graves’ disease was named after Robert J. Graves, MD, around the 1830’s. It is an autoimmune disease indicated by hyperthyroidism due to circulating autoantibodies, which is an antibody that attacks the person’s own body. The immune system attacks the thyroid gland, which causes it to produce too much thyroxine. Thyroxine is a hormone that helps control growth and also regulates metabolism in the body. While the thyroxine levels are high the patient’s metabolic rate increases, which can have an effect on their physical appearance as well as their frame of mind. Graves’ disease is the number one cause of hyperthyroidism in the U.S.
The main cause of hyperthyroidism Graves’ disease which affects quite a few people in the general population. This disease is characterized as an autoimmune disorder. This means that the body makes antibodies known as thyroid stimulating immunoglobulin that bind and over activate the production of thyroid hormones [3]. So in essence the antibody mimics the thyroid stimulating hormone and when the negative feedback loop is in affect the antibody still binds to the thyroid and T3 and T4 are over produced [2].
The purpose of this abstract is to examine Hashimoto’s thyroiditis, also known as Hashimoto’s disease, and chronic lymphocytic thyroiditis, which is an autoimmune disease. By researching this condition through medical journals, related associations, and relevant reports, I was able to gather information on the effects to health associated with this disease. The causes of Hashimoto’s thyroiditis are not clearly understood, however certain people are more likely than others to have this condition. Also, those with Hashimoto’s thyroiditis are more likely to have other autoimmune diseases. Normally, the condition develops slowly, and its signs and symptoms are indistinct, and can be similar to other conditions. To diagnose Hashimoto’s disease,
Hashimoto’s mainly affects women who are middle aged, but can affect, men, and children of any age. It has been established that Hashimoto’s is seven times more common in women
Hashimoto’s Thyroiditis, also called Hashimoto’s disease is an autoimmune disease in which the body’s immune system attacks the thyroid gland. It was named for the Japanese surgeon who discovered it in 1912 The thyroid is a small butterfly shaped gland in the front of the neck. The thyroid makes hormones called T3 and T4. These hormones regulate metabolism. The thyroid is controlled by hormones of the pituitary gland, which is also called the “master gland.” It is a pea-sized gland located in the base of the brain which, among others, makes thyroid stimulating hormone, or TSH. TSH stimulates the thyroid to make thyroid hormone. With Hashimoto’s disease, the thyroid cells are damaged resulting in the inability to make enough thyroid
Graves’ disease is autoimmune that effects the thyroid in front of the neck. This thyroid creates T3 and T4 which helps regulate how the body uses energy. We have a small gland called pituitary in the brain that helps the thyroid regulate the hormone level properly. With grave’s disease the immune system creates antibodies that act like TSH (thyroid stimulating hormone) which than makes the thyroid to create more hormones than what the body needs to have. This is called hyperthyroidism. Graves’ disease causes the body to speed up such as the heart and the metabolism. The symptoms for graves’ disease are goiter (enlarged gland) Anxiety and irritability, A fine tremor of your hands or fingers, Heat sensitivity and an increase in perspiration
Graves’ disease is an autoimmune disease in which the over activity of the thyroid gland causes the overproduction of the thyroid hormone. This disease was described by Robert J. Graves a doctor from Ireland and is also known as Basedow’s disease. Even though there are several disorders that may result in hypothyroidism, grave disease is one of the most common type of hypothyroidism that occurs in 1 percent of U. S population (Anderson 2010). Furthermore, Grave disease is a disease that can affect anyone, but is more common amongst females before age 40. Concerning, grave disease will attack the immune system making antibodies that will cause the thyroid to enlarge and produce more than the amount of thyroid hormone that your body will need. These hormones that cause the thyroid to enlarge are called thyroid stimulating immunoglobulins. Thyroid stimulating immunoglobulins are antibodies that tells the thyroid gland to become more active and release excess amounts of thyroid hormone into the blood (U.S. National library of medicine).
Unfortunately there are no specific preventative measures that could avoid this disease. However, knowing the symptoms ahead of time has an advantage. The sooner you recognize and catch this disease the sooner treatment can be applicable. This could be also known as primary prevention, being educated about the disease and how it can affect ones life.
The thyroid gland is very important in proper functioning of the human body. The hormones it releases are vital in regulating growth and metabolic reaction. The thyroid gland is relatively small (about 20g) and is located at the base of the neck, connected to the windpipe and voicebox. Its structure may be described as ‘butterfly-shaped’ as it is composed of two connected lobes. See image:
The following essay describes one of the most deceiving, yet common immune deficiencies today. Approximately 12 percent of the entire population world wide suffers from some type of thyroid disease. In the United States, this means roughly thirty million adults (Rosenthal, p.1). The focus of this paper is Graves’ Disease a type of hyperthyroidism that can mask itself in many forms such as weight gain or loss, depression, sleep disorders, tremors, and heart problems to name a few. This paper will define Grave’s Disease, give the symptoms, how the body and organs can be affected by an overactive thyroid, and the treatments currently used to