Question: What is the appropriate therapy for treating hashimotos induced hypothyroidism?
Background: An 83 year old female is taking her levothyroxine medication to help treat her thyroid disorder induced by Hashimoto. She has been taking this medication for thirty years. While always being adherent to taking her medication, she has never really understood what Hashimoto thyroiditis actually is, or why levothyroxine is the best choice of therapy for treating her hypothyroidism caused by the disease. She is also positive for hypertension, GERD, and insomnia.
Response: Hashimoto’s thyroiditis is characterized as a type of immune disorder and is the leading cause of hypothyroidism in America.1 The gradual failure of the thyroid is due to an autoimmune disorder that is causing glandular destruction.2 Thyroxine (T4) and triiodothyronine (T3) are two hormones
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According to one study found, this disease is seen more often in people between the ages of 45 to 65 years old.2 Another epidemiologic study also showed a female predominance of 10:1 to 20:1, and that the disease is more commonly seen in women rather than men.2, 5 During this study, 102 families were chosen to be observed and were made up of 540 individuals to determine if there is a significant genetic component to Hashimoto thyroiditis.5 While a high percentage of adults who had an autoimmune disorder such as trisomy 21 or Turner syndrome showed greater risk for having Hashimoto thyroiditis, a small group of about 20 percent had an indistinguishable clinical hypothyroidism much different from Hashimoto thyroiditis.5 Finally, an analyses of genome linkage in families with Hashimoto thyroiditis showed evidence that some loci, like chromosomes 6p and 12q, could be harboring genes that are already linked to this
Laboratory Report/ Miranda Tefft/ Homeostatic Imbalances of Thyroid Function/ Aline Potvin/ 11.18.2014/ Page [2] of [3]
2. The subject who was diagnosed with secondary hypothyroidism was given levothyroxine (synthetic Thyroxine). After 6 weeks of
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Hypothyroidism, while a common disorder, is often misdiagnosed due to its ability to mimic other common health problems. A simple, yet specialized blood test, coupled with a complete medical history, will allow the experts at RCMC Medical Center to not only diagnose the problem in a timely manner, but also develop a treatment plan based on the results, and your personal lifestyle, with the end goal of returning you to the level of health and wellness you
Graves ' disease is an immune system disorder that results in the overproduction of thyroid hormones (hyperthyroidism). The thyroid gland is an important organ of the endocrine system. The gland is located at the front of the neck above where the collarbones meet. This gland releases the hormones thyroxine (T4) and triiodothyronine (T3), which control body metabolism. Controlling metabolism is important for regulating mood, weight, and mental and physical energy levels. When the body makes too much thyroid hormone, the condition is called hyperthyroidism. Graves disease is the most common cause of hyperthyroidism and is most common in women over age 20. But the disorder can occur at any age and can affect men as well. Some of the symptoms of Graves diseases are
The exact mechanism of the autoimmune disease is unknown. Some of the medications that increase the risk of Hashimoto’s disease are called interferon, lithium, and amiodaron. The environmental radiations that one would be exposed to can increase the risk of getting hypothyroidism as well as having the Hashimoto’s Disease. The symptoms of the disease can develop after a pregnancy and a viral illness. Symptoms of Hashimoto’s disease tend to develop slowly over a period of several years. There are several different symptoms a couple of the visual symptoms are the enlargement of the thyroid and growth of the nodular. Other symptoms for the disease are that of being fatigue, having an intolerance for the cold, the menstrual cycle changes as well as infertility, can have an unexplained weight gain can happen and many more symptoms. There are some experiences of the patient having tenderness and prolonged pain, but pain is not a common symptom of the
Hashimoto’s Thyroiditis is considered an autoimmune disorder of the thyroid, first discovered in 1912, by a Japanese doctor, Hakaru Hashimoto. Hashimoto’s Thyroiditis disease is currently considered a genetically predisposed disorder caused by both environmental and endogenous conditions. Genetically predisposed Hashimoto’s Thyroiditis, occurs more often in Caucasians over other ethnicities. Environmental factors that produce the autoimmune disorder are infections, disproportionate iodine intake, drugs, as well as chemical and radiation exposure, according to Syrenicz, Anhelli (2013) This paper will discuss the importance of Hashimoto’s Thyroiditis disease, symptoms, Metabolic and Physiological effects, treatment options, and side effects associated with treatments.
Hashimoto thyroiditis is a common disease caused by hypothyroidism. The immune system cells attack the thyroid gland, causing inflammation and eventually destruction of the gland. This reduces the thyroids ability to make hormones. These hormones are known as thyroxine (T4) and tri-iodothyronine (T3) (Better health channel 2015).
III. Today I want to inform the class of Hashimoto’s disease and how it is an autoimmune disease, the leading cause of hypothyroidism, and the diagnoses and treatment of the disease.
When looking at my genogram, I see a strong genetic presence. Hypothyroidism has been diagnosed in my father, my grandmother on my mom’s side, my mother, all three of my mother’s sisters, one female cousin on my mom’s side, and me. This being said, all adult females on my mother’s side are diagnosed with hypothyroidism. Each of them were diagnosed in their adulthood, where as I was diagnosed at the age of 5. I believe that the early onset was in association with my Type 1 Diabetes. However, it seems to me that there is a clear genetic disposition running in my family. By analyzing my familial, I have concluded that the younger females in my family are also at high risk of developing hypothyroidism at some point in their
Hashimoto's is an autoimmune disease, also known as Chronic Lymphocytic Thyroiditis. The thyroid is part of the endocrine system and it is below your adam's apple in your neck. In this case, your thyroid is "attacked" by your immune system, which can cause hypothyroidism. Hypothyroidism is the result of an underactive thyroid function, similar to Hashimoto's where your thyroid "retires" and quits functioning.
The main cause of hyperthyroidism Graves’ disease which affects quite a few people in the general population. This disease is characterized as an autoimmune disorder. This means that the body makes antibodies known as thyroid stimulating immunoglobulin that bind and over activate the production of thyroid hormones [3]. So in essence the antibody mimics the thyroid stimulating hormone and when the negative feedback loop is in affect the antibody still binds to the thyroid and T3 and T4 are over produced [2].
Scientifically, Hashimoto’s Disease is, “a condition in which your immune system attacks your thyroid, a small gland at the base of your neck. The thyroid is a part of your endocrine system, which produces hormones that coordinate many of your body’s activities. The resulting inflammation from Hashimoto’s often leads to an under active thyroid” (Mayo Clinic.) Unfortunately, my thyroid didn’t work properly, and my body attacked it because of this.
My patient is a 30-year-old mother of two who presented with symptoms of fatigue, cold intolerance, and tearfulness. She was later diagnosed with Hashimoto’s Thyroiditis six months after the birth of her second child. With the addition of a thyroid hormone, prescribed by her doctor, the patient is doing well and living an active life with her husband and two children.
e. People who have had a thyroid problem before, received radiation for a thyroid problem, or had surgery on the thyroid are most likely to develop hypothyroidism.