preview

Haemophilus Pneumonia Case Review Sheet

Decent Essays

A 68-year-old female presents to her local physician’s office with a 4-day history of productive cough, chills, and fever. She has had no recent hospitalizations or recent use of antibiotics. Her temperature is 38.4·°C (101 °F), blood pressure is 144/84 mmHg, respiratory rate is 25 breaths/minute, heart rate is 100 beats/minute. Crackles are heard in the right middle lung field. She is oriented to person, place, and time.
Pertinent laboratory studies show WBC of 12/mm3, sodium of 135 mmol/L, BUN 18 mg/dL. A radiograph of the chest is seen in the image. The patient is best treated as an:

A. Iinpatient with ceftriaxone for 10 days.
B. Iinpatient with levofloxacin for 7 days.
C. Ooutpatient with ampicillin-clavulanate for 5 days.
D. Ooutpatient …show more content…

This patient has right middle lobe pneumonia as evidenced by the lung sounds and radiographic evidence, along with her fever, chills, and productive cough. The most common pathogen for an otherwise-healthy, middle-aged adult would be Streptococcus pneumoniae. Respiratory viruses, Haemophilus influenzae, and atypical pathogens (Mycoplasma pneumoniae, Legionella spp, Chlamydia pneumoniae, or C. Chlamydia psittaci) are also causes of community-acquired pneumonia (CAP). Based on her CURB-65 score (an acronym for predicting mortality in community-acquired pneumonia; Confusion of new onset, blood Urea nitrogen greater than 7 mmol/L, Respiratory rate of 30 breaths/minute or greater, Blood pressure less than 90 mmHg systolic, or diastolic blood pressure 60 mmHg or less, age 65 or older) , this patient meets the criteria for outpatient management. Outpatient management is generally carried out via appropriate antibiotics for 5 days. Symptoms should generally begin to improve with resolution of fever within 24–-48 hours after initiation of antibiotics and improvement of cough within 3–-6 days. If a patient doesn’t begin to improve within 48–-72 hours after initiation of therapy, they he or she should be reevaluated. All patients will need follow-up a few days after initial presentation to determine if they are improving and if there are any complications. A Rrepeat chest Xx-ray may be performed, but radiographic evidence of improvement is likely …show more content…

Macrolides inhibit protein synthesis by binding to the 23S rRNA of the 50S ribosomal subunit to block translocation. Fluoroquinolones block replication by inhibiting DNA gyrase (they relax topoisomerase II and add a supercoil) and topoisomerase IV. Beta-lactams bind the penicillin-binding proteins to block transpeptidase cross-linking of peptidoglycan. Treatment with any antibiotic should be for at least 5 days, and should not be stopped until the patient is afebrile for 48–-72 hours. Therapy should not be stopped if the patient has a heart

Get Access