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Gene Cards Assignment

Satisfactory Essays

Moreno Diego Gene Cards Assignment 09-26-17 Gene: BAP1 1. What type of mutation it is (loss of function, gain of function—look up ANY terms up in your book if you don’t know what they mean! The BAP1 gene belongs to the ubiquitin hydrolase subfamily of deubiquitinating enzymes. It is a recessive mutant gene. 2. Does it act in a dominant or recessive manner? Bap1 acts as consistent recessive cancer susceptibility gene. 3. What is the affect of the mutation on the cell cycle? BAP1 is a recessive mutant gene with a mild growth defect. The growth defect spread in heterozygous mutants. BAP1 enhances the phenotypes and according to environmental factors it can modulate mutant combinations. 4. Can it be inherited? (predisposition). Yes,

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