preview

Gabapentin Research Paper

Satisfactory Essays

Gabapentin Gabapentin is an anti epileptic medication which is used to treat variety of conditions like epilepsy, neuropathic pain, hot flashes, diabetic neuropathy, post-herpetic neuralgia, and central neuropathic pain. MOA Gabapentin has similar in structure to the endogenous neurotransmitter GABA, gabapentin has not been shown to bind to GABA receptors at concentrations at or below 1 mM. Gabapentin modulates the action of glutamate decarboxylase (GAD) and branched chain aminotransferase (BCAT), two enzymes involved in GABA biosynthesis and it had shown no interaction with the sodium or L-type calcium ion channels

Get Access