Furosemide Case Study

To begin the separation of the sucrose from the Panacetin, approximately 3 grams of Panacetin was transferred to a 125-mL Erlenmeyer flask. Added to the flask was 50 mL of dichloromethane to dissolve the Panacetin to aid in the separation. A fluted filter paper was used to filter the Panacetin and dichloromethane mixture by gravity using a glass funnel. The remaining filtrate was set aside than transferred to a separatory funnel and the substance on the filter paper was dried and weighed. The filtrate was extracted with 2 increments of 25-mL portions of aqueous 1 M sodium hydroxide. During this step the filtrate in the separatory funnel was shook and vented 3 times.

Mr. K. B’s kidneys should be compensating for his fluid losses and electrolytes by excreting more acids and

The makeup of a compound drastically changes its intermolecular forces (IMFs) with the polar silica gel of a TLC plate; this concept is responsible for the variability of Rf values observed throughout the course of lab. The weaker the IMFs, the further a compound will travel through the silica. For instance, ionic interactions are the strongest IMF, but were not present during this experiment. H-bonding IMFs had the greatest impact for our specific compounds. Resorcinol and 3-chlorobenzoic acid exhibited low Rf values, due to its ability to H-Bond to silica’s hydrogen donors and oxygens acceptors (See graph 1). Both were adept to strongly H-bonded to silica because the compounds contained at least 1 H-donor and 2 H-acceptors. Thus, stronger/more

Introduction This experiment was undertaken in order to create stilbene dibromide. Bromine is added through electrophilic addition in attacking the double bond. This experiment was also executed to determine the stereochemistry of this addition reaction, whether it created meso products or d,l products. Data and Results Initially, 0.9 grams of stilbene were added to the solution.

Upon the addition of water, it was noted that a layer separation occurred and the water layer remained on top, with the 2-methylphenol layer on the bottom layer. Then, conversion calculations were performed to determine the appropriate amount of 3M NaOH to be added to the 2-methylphenol solution. From the calculations, it was determined that 1.08 mL were to be added. 3M NaOH itself was a cloudy solution in appearance and upon the addition of 3M NaOH to the 2-methylphenol solution, it was noted a color change occurred and it became a yellow-green solution. Following this, the same calculations used previously, were used to determine the appropriate amount of sodium chloroacetate, which was found to be 0.38 g (3.26 mmol). Sodium choloroacetate was a white, crushed solid that was then combined with 1 mL of water and was swirled until the sodium chloroacetate completely dissolved. This sodium choloracetate solution was then transferred to the 2-methylphenol solution by the use of a medicine

16) After giving Lasix IV to a patient with heart failure, multiple runs of ventricular tachycardia appears on the monitor. Which of the following electrolyte imbalance should the nurse suspect?

Furosemide (lasix) works by blocking the re-absorption of sodum, chloride, adn water in the kidney tubules. It causes the sodium, cloride, and water to be excreted as urine. Lasix cause an increased output of urine.

The purpose of this virtual lab is to observe the acid-base balance in the urinary system by how PCO2 and blood pH affect the H+ and HCO3- in the urine. The renal compensation is a mechanism that shows the kidneys manage to change pH in correct way if the respiratory system is not healthy. The kidneys are two organs that help remove wastes and extra fluids out of the body. The acid-base balance is when the blood need to keep the balance of

3. What would happen to the amount of H+ secreted into the renal tubule if the activity of the Na+ /K+

A stock solution of carbachol was provided with a concentration of 10mM. a serial dilution was carried out to create three solutions of carbachol with concentrations of 1mM, 0.1mM and 0.01mM. the six concentrations were 10nM, 30nM, 100nM, 300nM, 1µM and 3µM. The six carbachol FBC’s were worked out using this equation [FBC]=([drug concentration]×volume aded )/(volume in tissue vessel) the FBC’s were then calculated to be: 1x10-8 , 3x10-8 , 1x10-7 , 3x10-7 , 1x10-6 , 3x10-6. The six carbachol concentrations were created from adding 50µl or 150µl from each of the three serial dilutions. A chart recorder was attached to the rat ileum to record any biological responses.

Acetazolamide is usually administered every eight to twelve hours orally while epinephrine is administered intramuscularly. Acetazolamide is a diuretic that stimulates the excretion of insulin and thereby stabilizing potassium and blood glucose. This drug is often prescribed to horses that are being fed high-potassium feeds either to stimulate growth in growing horses or for show horses eating high amounts of alfalfa. This drug can be used long term and restrictions in competition vary with the different breed registries. Hydrochlorothiazide is also variable restricted in competitions because diuretics can be used to cover up the use of illegal drugs. Sharon Spier, DVM suggests that inducing the movement of potassium across the membrane of the cell via insulin through feeding corn syrup or grain can be helpful in helpful in suppressing clinical signs. Hydrochlorothiazide taken every twelve hours orally can also be helpful in preventing attacks because it also is a diuretic and promotes the excretion of excess

The purpose of the experiment was to compare antacids by the amounts acid they neutralize to find the most effective antacid. Finding the most effective antacid is important because it will help others by allowing them to choose the best product for their heartburn. Titration is the process of which the unknown solutions concentration reacts with a known solution concentration. During the experiment, titration was used to calculate the moles of HCl neutralized by the antacid in this case was gelusil, by knowing the moles of HCl initially added to the flask and moles of HCl neutralized by the NaOH.

Thiazides diuretics reduce sodium reabsorption that leads to increased fluid loss, decrease plasma volume and extracellular fluid. (Drugs.com 2012). Other means of depleting potassium from the body are malignant hypertension (vascular), Type 1 and 2 renal tubular acidosis (Renal), trauma, and diarrhea (Buttarro et. al., 2017). To be able to diagnose Hypokalemia it is important to be aware of the signs and the

Furosemide 80 mg is a potent diuretic, which may cause the loss of potassium and magnesium.

What was the final bath concentration of noradrenaline you used? Briefly describe the response of the ileum to the direct addition of noradrenaline.