Benign childhood epilepsy with centrotemporal spikes (BCECT) is the most common epilepsy syndrome in childhood and accounts for 15% - 24% of all paediatric epilepsy cases between 5 and 14 years of age (Miziara et al., 2012), and despite having an IQ within the limits of normality, approximately 15–30% of affected children show some degree of slight cognitive deficit during the active epileptic phase (Pinton et al., 2006). This has put the assumedly benign nature of BCECT under debate (Völkl-Kernstock et al.,2009).
Although the association between epilepsy and cognitive deficits has been documented in numerous studies, this relationship has remained poorly explored in children with epilepsy (Krause et al. 2008). The impact of epilepsy on developing
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ERD has been observed during cognitive and attentional tasks (Dujardin et al., 1993). ERD is expected to be useful in clinical practice as an index reflecting abnormal cognitive functions specific to neurological and psychiatric …show more content…
Our study carried out on fifty (50) children divided into two groups, the patient group included 30 epileptic children presenting with benign childhood epilepsy with centrotemporal spikes with normal physical and mental development and the control group included 20 age and sex matched healthy children.
The methods of assessment in our study included for both groups EEG recording, neuropsychological and behavioral measures, ERP (P300) averaging and quantitative EEG frequency spectral analysis to measure Alpha power ERD and ERS in six different brain regions (anterior, central and posterior over both sides), in addition to the clinical history taking, examination and brain imaging of the patient group.
Our statistical data showed that the ages of the patient group ranged from 5.5 to 12.5 years with a mean of 8.84 ± 2.3 and ages of the children at onset of the disease ranged from 2 to 11.5 years with a mean of 7.36 ± 2.85 and this group included 17 males (56.7%) and 13 females
Firstly, Epilepsy diagnosis is higher in young children then in adults and every 1 in 200 children has epilepsy. This means that most young children cannot have a proper education since they experience unexpected seizures and may have to have a carer or adult with them at all times. Also, behavior issues are constantly being linked with epileptic children due to low self-esteem from overprotection and embarrassment about their ‘disability’. Many parents of epileptic children feel out of control, and give their child too much leeway in other parts of life – this also causes more behavioral issues. If we simply had a cure for epilepsy, all of these children could be saved.
People uneducated about Epilepsy may have confused thoughts on what it really is. People have these "notions," which are partly or entirely not true. So, throughout this research paper, these notions will be proven untrue, mostly by factual information given by
Examining the three studies closer, several flaws in design began to appear which questioned the reliability of the result. Two of the studies included 230 children while the third study contained only 180. It was noted that the time frame of monitoring seizure re-occurrence was much different also. One study monitored within 6 months while another monitored between 24 months for those treated with either an antipyretic or a placebo.
Seizures may arise at any stage of age, but certain periods of life present a higher risk for their emergence. The frequency of seizures in the epileptic population varies widely. Some epileptic experiences only two seizures in a lifetime, and other may suffer 100 of attacks daily. Approximately 25 percent of epileptic experience seizures that are uncontrolled by current forms of
Seizure disorders, according to the Mayo Clinic (2015), affect approximately 1 in 26 people in the United States. Persistent, or chronic, seizures result from a condition called epilepsy, a neurological disorder of the central nervous system. It can affect anyone regardless of age, but is more common during early childhood and after age 60. Given the number of people that seizure disorders, such as epilepsy, affect, it becomes helpful to gain a foundational understanding of the disease, including some of the causes, symptoms, and treatments available.
With ever-increasing cases of pediatric epilepsy, studies detailing the etiology of epilepsy and its association with developmental delay are progressively
Epilepsy is a brain disorder in which individuals have recurrent seizures. Seizures can occur in children and adults of any age. There are around 50 million people in the world who has the disorder. Individuals in developing countries are at a higher risk for developing the disorder. Seizures occur due to hyper-excitability and hyper-synchronization of neurons. Action potential transmits messages and it leads to depolarization. When neurons are uncontrollably depolarizes because of hyper-excitability due to too little inhibition, it cause a seizure. Seizures can last from a few seconds to a few minutes. As spontaneously they can develop is also as fast and spontaneous they can end.
We tested five subjects with GTC epilepsy (n=5, Women, over 19 year old) and five controls. All subjects were matched in gender, age and education. Importantly, they were all matched in terms of educational levels and seizures onset. All GTC patients were on treatment since early age, between 12 and 16 years old. Their ages were above 19 and up to 41 years old and their controls are matching them. Additionally, we screened them for the absence of any neurological or psychiatric disorders that could interfere with epileptic symptoms. We allowed our subjects to perform AEALT, (Myers, et al., 2000, Myers, et al., 2003, Herzallah, et al., 2010 and Myers, et al., 2011), after they passed the average scores of several Intelligence Quotient (IQ) subtests, which represented Wechsler Intelligence Scale for Children, (WISC). The original WISC (Wechsler, 1949) is an adaption of several of the subtests used for the Wechsler Bellevue Intelligence Scale (Wechsler, 1939), which also proposed several specific subtests. These subtests were organized into Verbal and Performance scales, and provided scores for Verbal
Each year, one in one hundred people in the United State develop epilepsy, but there is a less common type of epilepsy. It’s called febrile-infection related epileptic syndrome, more commonly known as FIRES. I happen to know one of the few people who have this type of epilepsy. Her name is Kailee, and she goes to my brother’s school. She was even in some of his classes. This type of epilepsy occurs in school-aged children between the ages of six and seventeen (“What is FIRES?”). It starts with a mild febrile illness that lasts anywhere from four days to two weeks. Febrile illness is when someone has a fever but they aren’t sick with anything else (“Febrile Illness”). When Kaylee was at this point, her mom thought she had the flu. This is very common, as the flu presents itself as a fever in many children. Then, the child starts to have seizures. The seizures occur very quickly, and the child needs to be hospitalized immediately at this point. Seizures the children experience are non focal, meaning they have no consistent starting point or ending point in the brain (“What is FIRES”). The disease is slightly more prevalent in boys than girls, but there is no known reason as
Neurocognitive disorders are classified by significant cognitive decline from prior functioning, affecting memory, speech, communication, behavior, and the ability to complete regulatory tasks. In some cases of neurocognitive dysfunction the condition does not progress, and although rare, some people may even experience improvement. Types of neurocognitive disorders include delirium, mild neurocognitive disorder, major neurocognitive disorder, anxiety, mood, and psychotic disorders, and Alzheimer’s disease. Just as there are many origins of neurodevelopmental disorders, there are also a wide array of causes of neurocognitive disorders including brain disorders,
In today’s society, many different kinds of school educations for children and teenager are available. Teenagers can attend a regular high school, a private school or they can get homeschooled. Most of the teenagers with epilepsy are able to attend a regular school because they have normal intelligence. Especially because of the fact that, if the teenager needs special aids, the most schools are able to offer this. However, it is always important to keep in mind that a teenager with epilepsy is able to learn as well and efficient as other teenagers.
Epilepsy is a disorder that compromises a lot of a child's independence. Many are doubtful they will ever drive a car. Some are concerned that their Epilepsy will get in the way of them becoming a parent. Many fear that eventually, their seizures will be what kills them. After researching about the effects of Epilepsy has on the life if not only adolescents, but on all epileptics, I have found that it is one the most difficult disorders to adjust living with. Epilepsy is a very crippling disorder, taking away most of a person's independence. But, there are also ways to overcome these struggles. With the support from loved ones, many Epilepsy patients are able to live their lives the same as any other person- one day at a
Epilepsy is a condition in which a person has two or more seizures affecting a variety of mental and physical functions. Epilepsy is one of the oldest conditions of the human race. Epilepsy Awareness is important because Epilepsy is a widely misunderstood disorder. The reason that Epilepsy has been misunderstood has been mainly due to research not being conducted until the middle of the nineteenth century. There are six main types of seizures and many treatments that can assist an epileptic patient. Many facts and myths exist about a person who has Epilepsy, which, is why it is an important disorder to understand. A person living with Epilepsy can typically have a normal life after seeking medical advice from doctors.
Prediction of epileptic seizures at an early stage increases the effect of medication and more patients can be treated accordingly thus improving the quality of life of the patients. For the proper treatment, physicians need to know if and when the seizure occurs as many medical decisions depend on detailed information about the seizure type and its origin in the brain. Electroencephalogram (EEG) monitoring is the golden standard for the diagnosis of epilepsy. An EEG investigation provides the aforementioned information about the continuous unusual nerve cell activity in the brain and a detailed seizure characterization in order to resolve therapeutic options, particularly in the absence of a response to medication. During an EEG investigation, the physicians place electrodes on your scalp which sense and record the electrical motion taking place in your brain which is then examined to find unusual activity, which may signal epilepsy. The Fig-2 shows a typical EEG recording setup wherein the electrodes are placed on the
underlying cause can be determined. Seizures occur as a result of abrupt, explosive, unorganized discharges of cerebral neurons. This causes a sudden alteration in brain function involving sensory, motor, autonomic and/or psychic clinical manifestations.