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Event Related Synchronization Method

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Benign childhood epilepsy with centrotemporal spikes (BCECT) is the most common epilepsy syndrome in childhood and accounts for 15% - 24% of all paediatric epilepsy cases between 5 and 14 years of age (Miziara et al., 2012), and despite having an IQ within the limits of normality, approximately 15–30% of affected children show some degree of slight cognitive deficit during the active epileptic phase (Pinton et al., 2006). This has put the assumedly benign nature of BCECT under debate (Völkl-Kernstock et al.,2009).

Although the association between epilepsy and cognitive deficits has been documented in numerous studies, this relationship has remained poorly explored in children with epilepsy (Krause et al. 2008). The impact of epilepsy on developing …show more content…

ERD has been observed during cognitive and attentional tasks (Dujardin et al., 1993). ERD is expected to be useful in clinical practice as an index reflecting abnormal cognitive functions specific to neurological and psychiatric …show more content…

Our study carried out on fifty (50) children divided into two groups, the patient group included 30 epileptic children presenting with benign childhood epilepsy with centrotemporal spikes with normal physical and mental development and the control group included 20 age and sex matched healthy children.
The methods of assessment in our study included for both groups EEG recording, neuropsychological and behavioral measures, ERP (P300) averaging and quantitative EEG frequency spectral analysis to measure Alpha power ERD and ERS in six different brain regions (anterior, central and posterior over both sides), in addition to the clinical history taking, examination and brain imaging of the patient group.
Our statistical data showed that the ages of the patient group ranged from 5.5 to 12.5 years with a mean of 8.84 ± 2.3 and ages of the children at onset of the disease ranged from 2 to 11.5 years with a mean of 7.36 ± 2.85 and this group included 17 males (56.7%) and 13 females

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