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Epstein Barr Virus Analysis

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Epstein - Barr virus (EBV) is an enveloped, dsDNA virus, member of the Herpesviridae family and Gammaherpesvirinae subfamily and it is a common pathogen, currently present in over 95% of the adult population (Murray, 2012). The virus is the primary cause of infectious mononucleosis both in childhood and adulthood. The disease is caused by proliferation of infected B cells and later their destruction by activated T cells (CTLs). EBV infects the mucosal epithelial cells, releasing progeny virus into the saliva and the B lymphocytes which leads to a long term, latent infection with little or no production of progeny virus (Acheson, 2011). Chronic EBV infection has been linked to multiple diseases including Burkitt’s lymphoma, Hodgkin disease,

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