Ebola Virus Disease ( Evd )

Ebola virus disease (EVD) is a rare deadly infection that is caused by one of five identified strains of the Ebola virus.

Although Ebola caught the world’s attention during the 1995 outbreak in Zaire, the first outbreak occurred in 1976. As the chart below displays, 71% of the people infected died as a result of Ebola during this first outbreak (Bulletin of the World Health Organization, 56 (2): 247-270, 1978). With the current outbreak, this ratio has dramatically decreased as a result of scientific research leading to early detection, but the current infected population is more than 20 times the amount of any previous outbreak and this number continues to grow as no vaccine exists to prevent the disease.

One of the most recent Ebola outbreaks occurred in West Africa in March 2014, and it was the largest outbreak in history. Two cases came to the United States because of West African outbreak (Ebola in the U.S.). Ebola virus disease (EVD) has a high fatality rate of 40-50% due to its high hemorrhagic fever, and is one of the most serious viral diseases currently known. In some outbreaks, the fatality rate even reached up to 90%. The threat to the community is even greater because currently there are no therapeutic strategies or vaccines available for EVD (Ebola Virus Disease 2013-2014).

First discovered in the 1970’s, the ebola virus was contained to West Africa (“About Ebola Virus Disease”). Villagers’ diets consisted primarily of the resources readily available. Among these resources were fruit, vegetables, and animals, namely monkeys. Monkeys carried the ebola virus, and when people ate them, without proper cleaning and cooking techniques, they became infected. Ebola, formally known as Zaire Ebola Virus, is transmitted through bodily fluids like saliva, blood, semen, breast milk, mucus, sweat, tears, feces and urine. ("Ebola in West Africa."). Since it was introduced to a third world country, where hygiene is not regarded as important as survival. Without education, protection and segregated sewage, the virus began to spread. In days people were dying after spreading the virus to those closest to them (Waterman). The bodies, though dead, were still harboring the virus and

“The disease spread like wildfire” (Osterath). As the year 2014 went along more and more people knew that Ebola was as serious of a disease as any. Ebola started in Sierra Leone a country in West Africa. The first case was recorded in March 23, 2014 “It was the largest and longest ebola outbreak in history” (Osterath). The disease itself is relatively old as it was first seen in 1976 in the country of Sudan and the Democratic Republic of Congo. Ebola comes from people eating wild animals like bats and monkeys who are the natural carrier of the disease. The disease is most commonly transmitted by blood and other bodily fluids.The Ebola outbreak in Sierra Leone was one of the worst outbreaks in history. Ebola killed thousands of people and left the country and its people in a constant state of chaos.

Ebolavirus is responsible for highly lethal hemorrhagic fever. Like all viruses, it must reproduce its various components and assemble them in cells in order to reproduce infectious virions and perpetuate itself. To generate infectious Ebolavirus, a viral genome-protein complex called the nucleocapsid (NC) must be produced and transported to the cell surface, incorporated into virions, and then released from cells. To further our understanding of the Ebolavirus life cycle, we expressed the various viral proteins in mammalian cells and examined them ultrastructurally and biochemically. Expression of nucleoprotein alone led to the formation of helical tubes, which likely serve as a core for the NC. The matrix protein VP40 was found to be critical

The Ebola Haemorrahagic Fever, or Ebola for short, was first recognized as a virus in 1967. The first breakout that caused the Ebola virus to be recognized was in Zaire with 318 people infected and 280 killed. There are five subtypes of the Ebola virus, but only four of them affect humans. There are the Ebola-Zaire, Ebola-Sudan, Ebola-Ivory Coast and the Ebola-Bundibugyo. The fifth one, the Ebola-Reston, only affects nonhuman primates. The Ebola-Zaire was recognized on August 26, 1976 with a 44 year old schoolteacher as the first reported case. The Ebola-Sudan virus was also recognized in 1976 and was thought to be that same as Ebola-Zaire and it is thought to have broken out in a cotton factory in the Sudan. The Ebola-Ivory Coast was

Ebola, a virus which acquires its name from the Ebola River (located in Zaire, Africa), first emerged in September 1976, when it erupted simultaneously in 55 villages near the headwaters of the river. It seemed to come out of nowhere, and resulted in the deaths of nine out of every ten victims. Although it originated over 20 years

The first outbreaks of Ebola occurred in Africa between 1st September and 24th October 1976, there were 318 cases of the disease in northern Zaire. The outbreaks were centred in the Bumba Zone of the equator and most of these cases were recorded within a radius of 70km from Yambuku .There were a total of 280 deaths and only 38 serologically confirmed survivors.

Ebola virus disease (EVD) is a severe, often fatal illness in humans. EVD outbreaks have a case fatality rate of up to 90%. It belongs to the Filoviridae family (filovirus) and is commonly found in several African countries. Ebola was first discovered in 1976 near the Ebola River in what is now the Republic of the Congo. Since then, outbreaks have appeared irregularly in Africa.

This Ebola outbreak first began the jungles of West Africa and has spread throughout several countries in the area, but not the U.S. This is because of many factors, including traditional medical practices in Africa, lack of technology in many African areas, and access to advanced medical facilities in the U.S. The most significant of these is Africa’s lack of highly technological medical care.

The Ebola Virus disease (EVD) began at in December 2013 and was announced to the public at 23 March 2014 at Republic of Guinea, then to Prefecture of Macenta , 80 km to the east .

Ebola virus disease (EVD) formerly known as Ebola hemorrhagic fever is an often fatal disease caused by a virus. This virus can cause severe hemorrhagic fever in humans (Occupational Safety & Health Administration [OSHA], N.D.). With world worldwide attention for its high mortality rate, lack of effective treatment or vaccination EVD has become an important public health pathogen (Feldmann & Geisbert, 2011).

Ebola Virus Disease was given it 's name from the Ebola River in the Democratic Republic of the Congo. The disease first appeared in 1976 in two outbreaks occurring simultaneously. One occurred in South Sudan and the other in the Democratic Republic of the Congo. In the Democratic Republic of Congo it took place in a village near the Ebola River, hence its name. The most current outbreak in occurring in West Africa. Reports say that it is the most complex and largest outbreak since it first appeared. This current outbreak of the Ebola Virus Disease has had more deaths than all other appearances of the disease combined. The most effected countries include Guinea, Liberia and Sierra Leone. These countries have weakened health systems and very limited resources. With limited resources it makes it extremely difficult to stop the spread of such diseases. Therefore, Ebola appears in mainly in underdeveloped counties with limited resources and weak health systems.

in Kikwit, Zaire with 316 cases and 244 deaths; and two smaller outbreaks in the