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Diabetes Bidirectional Relationship

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Most studies show that the relation between diabetes and depression is a bidirectional relationship, so each condition increases the risk of having the other, and those studies either studied both arms of this relationship or one arm. One of the most recent studies by Chen and his colleagues was published in 2013,the study objective was to address the strength of association of the bidirectional relationship between type 2 diabetes and depression.The study was conducted by Chen and his colleagues and published in 2013 and it was also in agreement with previous studies like that done by Mekuz and his colleagues published in 2008. They used two cohort studies with the same source of the database to determine the link between depression and type …show more content…

The follow-up period was between 2000 and 2013, and onset of end points was identified from ambulatory care claims. He calculated the hazard ratio i.e. the incidence of becoming depressed and diabetic and the ratio between the two. And the first cohort analysis noted an incidence density (ID) of 7.03 per 1,000 person years (PY) and 5.04 per 1,000 PY for depression in diabetic and non-diabetic subjects, respectively. Which means that diabetes increases the risk of depression more than non-diabetic subjects, and hazard ratio (HR) of 1.43 (95% CI 1.16–1.77).The second cohort analysis noted an ID of 27.59 per 1,000 PY and 9.22 per 1,000 PY for diabetes in depressive and non-depressive subjects, respectively. This means that depressed patients are more likely to develop diabetes than non-depressed subjects, and HR of 2.02 (1.80–2.27).The two cohort studies provided evidence for the bidirectional relationship between diabetes and depression, with a stronger association noted for the depression predicting onset of diabetes since the HR was stronger (2.02) compared to that of diabetes predicting onset of depression (1.43).Thus, the risk of diabetes in depressed patients is more than the risk of depression in diabetic

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