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Cyp3 Lab Report

Satisfactory Essays

Genetic variations in CYP3A4 and CYP3A5 may cause differences in enzyme activity between individuals. These genetic variations cause differences in metabolism of substrates of CYP3A4 and CYP3A5, which includes many opioid drugs. Such differences in metabolism can cause toxic effects or loss of therapeutic efficacy and make drug choice and dose optimization challenging. Genetic variations in CYP3A4 and CYP3A5 may cause differences in enzyme activity between individuals. These genetic variations cause differences in metabolism of substrates of CYP3A4 and CYP3A5, which includes many opioid drugs. Such differences in metabolism can cause toxic effects or loss of therapeutic efficacy and make drug choice and dose optimization challenging. Genetic

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