Crvical Cancer Essay

I can draw from these results that as the chemotherapeutic drug concentration is increased the cell viability decreases. In HEPG2 the viability at the control was 100% but when the drug was added at concentration of 40µm the cell viability decreased to 2.62%. From these examples we can deduce that the chemotherapeutic drug added is successful in its use and that it is targeting the cancerous cells. The drug damages the genes present inside the cell line

Cervical Cancer is the second most common cancer for women yet it is the most common cancer of the reproductive system. According to the CDC in 2010 11,818 women in the United States were diagnosed with cervical cancer and 3,939 women in the United States died from cervical cancer. The most common type is squamous cell carcinoma. Human papilloma virus, otherwise known as HPV, is known to cause cervical abnormalities and has been linked to cervical cancer.

Some people are fortunate enough to have the ability to pay to get proper care. While others are not, as fortunate. Could you image having cancer, and making the decision if you had the time or money to be treated. Many people cannot even begin to fathom about making a choice like that. But Crissy Knibble was put in a situation where she might of have to.

Cervical cancer is the leading cause of cancerous death, in women, since 1950. Approximately 200,000 cervical cancer patients die each year in developing countries. Strains like HPV 16 and 18 cause about 70% of cervical cancer in women– one of the top causes of death in the world (WebMD, 2010, p.1). In the Unites States, about 10,000 women acquire the disease and 3,700 die annually Human Papilloma Virus (HPV) is directly associated as a cause of cervical cancer. This virus affects the skin and genital area and, in some cases, it can also infect the throat and mouth. Since the HPV is passed from one person to another through skin-to-skin or sexual contact, sexually active people are more prone to this virus. Merck

may help kill certain cancer cells and reduce the size of others. Evidence from one cell culture study

Cervical cancer is a disease in which malignant (cancer) cells form in the tissues of the cervix or cervix uteri. Cervical cancer is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in females worldwide with over 527,000 new cases 1,2 and perhaps the second most common cancer among women in the third world countries 3-5 It accounts for 9% of the total new cancer cases and 8% (more than 265,000) of the total cancer deaths among females.1,2 More than 80% of these cases and deaths occur in developing countries.1-4

Cancer is one of the leading causes of death worldwide as it can develop in almost any organ or tissue. Significant advances in understanding the cellular basis of cancer and the underlying biological mechanisms of tumour has been vastly improved in the recent years (Jiang et al. 1994). Cancer is a genetic disease which requires a series of mutation during mitosis to develop, its characteristics can be associated with their ability to grow and divide abnormal cells uncontrollable while in the mean time invade and cause nearby blood vessels to serve its need. Even though many people are affected by cancer today, the abilities which cancer cells have make it hard to find a single effective treatment for cancer. The focus of research now lies

The first option being the removal by surgery, the second operation would be cryoscopy or freezing of the cancer cells. The third would be a localized laser treatment to help remove the cancer cells. Although only a small patch of infected cells are able to be removed with these treatments. The treatment for cervical cancer if it is malignant is chemotherapy with radiation. However, even with this treatment the survival rate is reduced. Cervical cancer can be prevented to where women everywhere should have a reduced chance to no chance in acquiring cancer. The FDA has approved two shots that are given by doctors in order to help prevent cervical cancer. However, the two shots do not protect against all strains of HPV, therefore protection such as condoms should be used during

According to the Centers for Disease Control and Prevention (CDC), Human papillomavirus (HPV) infects roughly 20 million individuals in the United States with 6.1 million new cases each year. There is no cure for HPV, only treatment for associated health problems. There are more than 30 strains of HPV that affect more than half of sexually active individuals in their lifetime. Public health risks involve several types of HPV leading to precancerous lesions and causing 70% of cervical cancer. Cervical cancer, the second most common cancer, affects many women globally. In the United States, nearly 10,000 women are diagnosed with cervical cancer annually and 3,700 of those women die. It has been reported by American Cancer Society that with early

In Cytology the majority of the samples received are part of the NHS (National Health Service) cervical screening programme. This programme facilitates the screening of cervical smears slides, looking for abnormal cells in a woman’s cervix, that may go on to form cervical cancer. 99.7 % of cervical cancers are caused by a sexually transmitted infection called Human Papilloma Virus (HPV). There are over a hundred different types of the HPV virus and certain ones are counted as more ‘high risk’. 80% of the population will have HPV at some point in their lives and in most cases their immune system will get rid of it within a couple of years. Scientists still don't understand why some women are able to clear the infection, while in others the

Primary Prevention of Cervical Cancer Every year 14 million people learn they have cancer and 8 million people die from the disease around the world ("Number of Cases, Deaths, and Survivors," 2012). Cervical cancer is the fifth the most common cancer type. About 500,000 people get diagnosed yearly. Every other minute a woman dies of that type of cancer (Pruitt, 2012). It is predicted that 12990 women will be diagnosed with cervical cancer 4120 will die in United States this year (What are the key statistics about cervical cancer ?, 2016).

Research has demonstrated that there is a low level of awareness among college students regarding risk factors and symptoms of STIs that most threaten them, including HPV(Johnson 2014) According to {Bradley, 2005 #2414} cervical cancer kills a disproportionate number of women in developing countries, despite the fact that evidence-based secondary prevention methods exist . In the study carried out by {Gwag, 2003 #2415} it is found that many women do not attend screening programs because they are not aware of their risk of cervical cancer or of the benefits of screening and early detection and prevention. Several studies conducted in various South Asian countries have reported that between 50-85% of women were knowledgeable or aware of cervical

In the seminar given to us by Damien Samways, we were exposed to the research and discoveries linked to transmembrane transport mechanisms for selective drug delivery, specifically leading into selective permeabilization of cervical cancer cells. We learned that the beginning of the research was based mainly on the ATP and calcium in cells and how they could be used or manipulated for transport and permeabilization used to get drugs into cells and were faced with the question if this could have a therapeutic effect. The research was soon focused onto the P2x and P2y receptors of the cell, which are ion channels activated by ATP. Further research on the receptors determined that ATP could permeabilize cells and some channels within the cells transport therapeutic drugs using a process called selective silencing. With this information, the curiosity arose for the use of anticancer drugs with and intracellular target, although this process had known problems. The concerns included getting the drug across the plasma membrane of the cells and the fact that they only wanted the drug to get into cancer cells, not all cells. In the lab model, fluorescent cytotoxins were used to determine the uptake into the cells. A hypothesis was then made the ATP can permeabilize cells to some small fluorescent cytotoxins. Focus was then placed on the P2y receptors and the original idea of ATP, which can be used to increase the permeability of cancer cells and

Cervical cancer malignant cancer of the cervix uteris or cervical area. It may present with vaginal bleeding but symptoms may be absent until the cancer is in its advanced stages, which has made cervical cancer the focus of intense screening efforts using the Pap smear. About 2.2 percent of women carry one of the 2 virus strains most likely to lead to cervical cancer. One of the symptoms of Cervical Cancer is very Unusual amount of discharge.

3-hydroxy and 3-methoxy 2-styrylchromones have been reported to exhibit anti-rhinovirus activity. Two derivatives of dimethyldihydropyranon chromone and its analogues were found to be effective for anti-HIV-1 activity against a non-drug-resistant strain and even against multiple reverse transcriptase (RT) inhibitor-resistant strain (An et al., 2015; Semba et al., 2002; Vasselin et al., 2006; Wu et al., 2003; Yu et al., 2004). For the viability and growth of prostate cancer cells in vitro and prostate xenograft tumor development in nude mice model, signal transducer and activator of transcription 5 (Stat5) expression plays a key role. The transcription factor STAT5, a therapeutic target for treating various human cancers, have been also found to be inhibited by chromone-based inhibitors. Hepatocellular carcinoma being the sixth most frequent cancer worldwide, is of major health concern . It is a type of heterogeneous tumor closely associated with chronic liver diseases which often results in the occurrence of cirrhosis. For women, cervical cancer is the second most prevailing cancer globally and mainly emerges among female genital tract neoplasms. There are as many as 500,000 new cases each year worldwide, making cervical cancer responsible for the deaths of around 230,000 women per year