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Cognitive Dysfunction

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DISCUSSION
Decline in cognitive function after surgery, particularly in the elderly, has been anecdotally appreciated by the profession and public for many years. It is a well established phenomenon after hip, knee, abdominal, cardiopulmonary bypass and recent research reveals it to be a surprisingly common outcome after other types of major surgery.
Cognition is defined as the mental processes of orientation, perception, memory, and information processing, which allows the individual to acquire knowledge, solve problems, and plan for the future. It comprises the mental processes required for everyday living and should not be confused with intelligence. Cognitive dysfunction is thus impairment of these processes16 .It is usually expressed …show more content…

Galanakis P, Bickel H et al (2011)18 found that Postoperative Acute Confusional State (ACS) developed in 23.8% of the study sample, in 40.5% of the hip fracture group and in 14.7% of the hip joint replacement group. risk factors of ACS: higher age (OR = 1.14, 95% CI 1.07-1.22), prior cognitive impairment as measured by Mini-Mental State Examination (OR = 1.32 for each point less, 95% CI 1.06-1.64), depression (OR = 3.67, 95% CI 1.12-12.02), low educational level (OR = 3.59, 95% CI 1.14-11.25), and preoperative abnormal sodium (OR = 4.32, 95% CI 1.01-18.38). patients. They have found higher age as risk factor to develop …show more content…

In (2012)22 Postler A, Neidel J et al conducted a prospective cohort study of 60 patients older than 65 years (66.7% female, 33.3% male) who received THR. The cognitive function was measured preoperatively, one week and six months postoperatively by the mini-mental state test (MMSE). Shortly after surgery 4 patients (6.7%) developed postoperative cognitive dysfunction, which has recovered at six-months-follow-up. In 41 patients (68.3%) adverse effects were recorded. Postoperative anemia occurred as the most common adverse effects (n=32; 53.3%). They noted that during postoperative hospital stay older patients were at an increased risk for adverse effects. Rudolph JL, Jones RN, Rasmussen LS et al in (2007)23 conducted an International Study of Postoperative Cognitive Dysfunction recruited patients undergoing noncardiac surgery from 8 countries. In bivariable analysis, several vascular risk factors were significantly associated with the likelihood of delirium, including male sex, exposure to tobacco, previous myocardial infarction, and vascular surgery. After adjustment for age, tobacco exposure and vascular surgery were independent vascular risk factors for delirium. In addition, This study said male sex is at vascular risk factor and vascular

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