Cancer
Cancer is one of the leading causes of morbidity and mortality worldwide, with approximately 14 million new cases in 2012.2 The amount of new cases is expected to rise by about 70% over the next 2 decades. Cancer which causes nearly 1 in 6 deaths, is the second leading cause of death globally, and was responsible for 8.8 million deaths in 2015. Approximately 70% of deaths from cancer occur in low- and middle-income countries. In 2012 about 14.1 million new cases of cancer occurred globally (not including skin cancer other than melanoma).3 The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer.
The purpose of cancer tissue engineering is understanding cancer biology which is a
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When cell populations are used to form tissues and organs, proper 3D systems, with clinically relevant dimensions, are required to eventually scale up these findings into effective new treatments. 6
Cervical Cancer
Cervical cancer is one type of cancer happening from the cervix due to abnormal growth of cells. There are many reasons to cause cervical cancer. One of them is that the abnormal cells from other parts of body are able to invade or spread to the cervix and cause the abnormal growth. Unfortunately, in early stage, typically no symptoms are seen, and later symptoms may include abnormal vaginal bleeding, pelvic pain, or pain during sexual intercourse. What’s more, when bleeding after sex, it also may indicate the presence of cervical cancer.7
In the United States, it is one of the eight-most common cancer of women. According to researches, the data shows that Hispanic women are significantly more likely to be diagnosed with cervical cancer than the general population and their median age at diagnosis is 48. In 1998, about 12,800 women were diagnosed in the US and about 4,800 died. Among cancers of the female reproductive tract, it is less common than endometrial cancer and ovarian cancer. The rates of new cases in the United States was 7 per 100,000 women in 2004. Cervical cancer deaths decreased by approximately 74% in the
Cervical cancer is when there are malignant cells present in the cervix; it is developed in the lining of the cervix. A cervix is a narrow opening located at the bottom of the uterus that leads into the vagina. Cervical cancer mostly affects women between the ages of 40 and 55. This cancer can be prevented by screening for precancerous cells, and it can also be cured if it is detected at an early stage. Over the past few decades the number of cervical cancer cases has declined dramatically due to a more widespread screening of the disease. Today, it is estimated that 10,000 new
Cervical cancer is caused by the uncontrollable growth of cells in the cervix, the lower part of the uterus that opens into the vagina. Some signs of cervical cancer are abnormal bleeding in the vagina (between menstrual cycles, after sex, and after menopause), pain in the lower belly, pain during sex, and abnormal vaginal discharge.
Cervical carcinoma is the third most common gynecologic malignancy with an approximate 85% of the global burden is from developing countries, where it accounts for 13% of all female cancers [1, 2]. Even though there have been significant advances in surgical techniques, radiotherapy, and chemotherapy, there are still approximately 30% of these patients with invasive cervical carcinoma who die as a result of residual or recurrent disease [3].
Cervical cancer is a tumor of the cervix. The cervix is the part of the womb, which projects into the vagina. It measures less than one inch across and about one and a half inches in length. It is a block of a special type of muscle covered by a thin layer of surface cells. Cancer of the cervix develops in these surface cells, which first start to grow in an abnormal way (precancerous cells).
The possible difficulties when diagnosing cervical cancer, is that some of the symptoms can be associated with another disorder. So for example experiencing unusual vaginal bleeding is a sign of cervical cancer. However, it is also a symptom of Chlamydia a sexual transmitted disease/ infection. And so do not hesitate to visit your local GP is something does not seem right.
High-hazard HPV diseases can cause changes in the cells of the cervix and different territories that may prompt malignancies. Discovered early, the influenced tissues can be evacuated by means of cryosurgery or other surgical strategies. On the off chance that they are not distinguished and evacuated, tumor may create. Normal medications for cervical tumor are evacuation of a few or the greater part of the cervix, expulsion of some other influenced territories, for example, the uterus and encompassing lymph hubs, and chemotherapy or potentially radiation. Surgical intercession at any phase of treatment may prompt difficulties with pregnancy and labor.
Currently, cervical cancer remains one of the most preventable causes of cancer deaths. According to the Centers for Disease Control and Prevention, in 2014 12,578 women were diagnosed with cervical cancer and 4,115 died of cervical cancer (CDC, 2014). HPV, or the Human Papilloma Virus has been found to be the cause of cervical cancer in women. The Papanicolau test, or Pap test has been around for decades and it is the test where cervical cytology is examined for any change in the cells of the cervix that may lead to cancer. Early detection of cervical dysplasia or cervical cancer has prevented cervical cancer deaths. Currently, high-risk HPV
Cervical Cancer Early Detection Program Journal of Women’s Health 20(10):1479-84 doi: 10.1089/jwh.2010.2530. Epub 2011 Jul 20
Cervical cancer is a type of cancer that develops in a woman’s cervix, which is the entrance to the uterus through the vagina. There are glandular cells lining the inside of the cervix and they produce mucus. The cervix is covered with a layer of skin-like cells on the other surface, called ‘ectocervix. These cells of the ectocervix and glandular cells can become cancerous, by malignant tumours from cells that are able to invade the surrounding tissue and organs causing serious damage to it, by abnormal cell growth and tumour in the area. The area of the cervix that is most likely to be prone to cancer, is the opening area of the cervix or space within the cervix called the ‘endocervical canal’. This area is the narrow passage way which gives
The major risk factor for pre invasive or invasive cervical carcinoma is infection with the human papilloma virus (HPV). HPV DNA is detected in virtually all cervical cancers, with HPV subtypes 16, 18, and 31 identified most commonly. Other known risk factors include early age at first intercourse, number of sexual partners, and a positive smoking history. Cervical carcinoma spreads predominantly by local invasion and lymphatic metastasis. The most common metastatic sites include the vagina, parametrium, and pelvic lymph nodes ( 1,2,3).
The most important risk factor for cervical cancer is infection with the human papillomavirus (HPV). There are over 100 different types of HPV; however, most types of HPV do not cause cancer. At least 80 percent of women are exposed to the HPV virus during their lifetime. Most of the time, the body's immune system gets rid of the virus before it does
One of the most common signs for cervical cancer is abnormal bleeding or postcoital bleeding, which is abnormal bleeding after sexual intercourse caused by the irritation of the cervical cancer cells which bleed easily when touched. It is very important that if a woman notices any abnormal bleeding that they seek attention immediately before the cancer progresses into a worse stage. In more progressed cases of cervical cancer the
According to the Centers for Disease Control and Prevention (CDC), the leading cause of cervical cancer remains Human papillomavirus (HPV), a virus that passes from one person to another during sex.” (Centers for Disease Control and Prevention, 2015) . Although HPV is a common Sexually Transmitted Disease (STD), physicians suggest that all women over the age of 21 be tested for cervical cancer
In women, one of the most common cancers of course is breast cancer, in men prostate cancer and in men and women, lung cancer and colon cancer are common cancers. It is important to understand that the cancer that occurs in one individual is very different from the cancer that occurs in another. Everyone is different; a lung tumor in one person will be different from a lung tumor in another person. Once a diagnosis of cancer is made, the next obvious question is what do you do? There are several things that are really relevant, for example, the stage of the cancer which is information about where is the cancer?
More than half of sexually active people become infected with HPV at some point in their lives and whilst most will clear this infection naturally within two years, HPV can cause pre-cancerous cancer cells, which if undetected can develop into cervical cancer over time. In fact, the HPV strains 18 and 16 are the cause of over 70% of cervical cancers cases in women, with over 99% of patients with cervical cancer also having an HPV infection.